Freeze-Drying Process; Preparation - Christ Alpha 3-4 LSCbasic Operating Manual

NOTE
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2.2.2

Freeze-drying process

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2.2.2.1

Preparation

Version 11/2018, Rev. 1.9 of 01/12/2021 • sb
Translation of the original operating manuel
Fig. 8: Freeze-drying phases
Please find further information about basic principles, optimum
procedures and applications in the brochure "Smart freeze-drying", which
can be downloaded at www.martinchrist.de → [Applications] →
[Lyophilisation].
The main components of a freeze-dryer are:
•
vacuum drying chamber or drying manifold,
•
vacuum pump for generating a vacuum inside the drying chamber,
•
ice condenser for binding the water vapour that is released by the
product.
The ice condenser chamber must be clean and dry. Any water residues
from a preceding drying run must be removed.
The media drain valve and the aeration valve must be closed.
In the case of units that are equipped with a pressure control valve
(standard on LSCplus and LSCbasic units), the vacuum pump should be
warmed up ("warm-up") for at least 15 minutes prior to the start of the main
drying phase. Do not subject the vacuum pump to condensable gases until
the operating temperature is reached. In this way, the service life of the
vacuum pump can be extended.
Freeze-dryer Alpha 3-4 LSCbasic
2 Layout and mode of operation
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