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4
Operation
Two different columns in/Two detectors out
Figure 27
With this setup, a method can inject into Inlet 1 (and Column 1) while Column
2 is unused. Inlet 2 pressure is set at a low level that produces a small makeup
flow (at least 0.5 mL/min) through Column 2. A second method can reverse
the situation, purging Column 1 while analyzing with Inlet 2 and Column 2.
This can be useful in laboratories that frequently need to use columns with
different phases. Setup is the same as for the two-way splitter, except that
column flow in the calculations is now the SUM of the flows from Columns 1
and 2.
Since the bleed from both columns enters the detector simultaneously,
low-bleed stationary phases should be used.
52
Inlet 1
Inlet 2
Column 2
Column 1
Two different columns in/two detectors out
Aux EPC
Det 1
Splitter
Installation and Operation Guide
MSD
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