Warnings; Safety Devices - Leica CM1860 Instructions For Use Manual

2.2

Warnings

The safety devices installed in this instrument by the manufacturer only constitute the basis for accident
prevention. Operating the instrument safely is, above all, the responsibility of the owner, as well as the
designated personnel who operate, service or repair the instrument.
To ensure trouble-free operation of the instrument, make sure to comply with the following instructions
and warnings.
2.3

Safety devices

The instrument is equipped with the following safety devices: Handwheel lock and safety guard on the
knife holder.
Warning
CM1860 UV only: To prevent adverse health effects from UVC radiation, the UVC disinfection cycle can
be started only after the sliding window has been properly closed. Closing the window activates the
corresponding safety features.
The consistent use of these safety features and strict observation of the warnings and cautions in these
Instructions for Use will safeguard the operator by and large from accidents and/or personal injury.
Personal safety precautions
Warning
When working with cryostats, personal safety precautions must always be taken. The wearing of work
safety shoes, safety gloves, laboratory coat, mask and safety goggles is mandatory.
Chemical disinfection and UVC radiation can never be used as a substitute for manual protection in
accordance with laboratory regulations.
UVC disinfection is effective when disinfecting surfaces and air within the irradiated working area of
the Leica CM1850 UV, CM1860 UV and CM1950 cryostats at –20 °C (Table 1, see I. Maier certificate).
For powerful disinfection, we recommend irradiation for three hours (CM1850 UV/CM1860 UV/
CM1950). Vegetative bacteria including Mycobacterium tuberculosis, bacterial endospores (Bacillus
sp.) and fungi are killed during this time. Viruses including such resistant species as hepatitis are also
inactivated up to at least 4 log10 units (99.99 %).
Medium disinfection can be attained through short irradiation for 30 minutes (CM1850 UV/CM1860
UV/CM1950). This reduces vegetative bacteria including Mycobacterium tuberculosis and sensitive
viruses such as the influenza A virus (also including the highly pathogenic avian influenza virus
H5N1) and poliovirus by at least 5 log10 units (99.999 %). UVC irradiation within the working area of
the cryostats can provide reliable and efficient disinfection of surfaces and the air and significantly
reduces the risk of infection.
We recommend wiping off visible contamination in the cryostat with an alcohol-based disinfectant
prior to using the UVC lamp. The germicidal effect of the irradiation is restricted to the directly
irradiated areas, which is why UVC irradiation cannot be a replacement for regular chemical
disinfection of the cryostat chamber.
Leica CM1860/CM1860 UV
2
Safety
13