The Mixing Process - gako unguator EMP Quick Start Manual

The mixing parameters are general procedures used to produce the routine standard formula-
tions in pharmaceutical preparation of compounds.
In the following, these standard formulations will be defined and the recommended proce-
dure on weighing described. This will produce a code of practice for orientation. This does not
exclude other possible methods for optimization.
For mixtures with high liquid content, ensure that the ointment foundation on the jar bottom
is first carefully placed around the sealing lip. This enhances the leak tightness of the jar. For
jars of 200 ml and up an active substance proportion of less than 5 %, the active ingredient can
be filled alternating with the foundation ointment over two or more levels to speed up vertical
intermixture.
Solid components should be inserted on the side of the jar and covered with foundation. This
will prevent the solid materials to adhere onto the stirrer.

The Mixing Process

The gako unguator EMP is the result of continuous improvements of the gako unguator e of
the year 1997. This was a further development from the original unguator from the year 1994
featuring an automated lift arm, programmable mixing time and mixing speed.
The gako unguator EMP is equipped with two quiet and constantly usable permanent motors
and is the ointment mixing device for individual and bulk compounding from 15 ml up to 500 ml.
To prepare compounds homogeneously, the gako unguator EMP works in a rotation range from
300 up to 2400 rpm.
For every jar size different mixing parameters are already set in the gako unguator EMP. These
serves as recommended minimum mixing time and minimum mixing speed. They have to be
adjusted accordingly to each type of formulation.
Due to high rotation speed the levels 8 and 9 are not suitable for manufacturing in the jar sizes
300 ml and 500 ml, they are disabled in the mixing time selection.
The mixing time can be set from 5 seconds to 99:30 minutes and the mixing motor in 10 levels
from "0" to "9".
The exact rotation speed for each level are provided by the following table chart. The rotation
speed is measured in the unit rpm.
Level
Rotation speed (rpm) 300
After selecting jar size, mixing speed and time the lift arm will move into the loading position.
The new gako unguator jar can be easily loaded into the lift arm due to the quick-lock coupling.
0 1 2
600 800 1000
tab.: value chart rotation speed
3 4 5
1200 1400 1650
6 7 8
1900 2150 2400
chapter 4 - page 2
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