Calculated Parameters - NOVA BIOMEDICAL Stat Profile PRIME Instructions For Use Manual

B.2.2

Calculated Parameters

Calculated Bicarbonate Concentration [HCO
Bicarbonate Concentration (mmol/L) is calculated using the
Henderson-Hasselbalch equation:
pH = pK + log –————
where pH and PCO
pK = 6.091
α = 0.0307 = solubility coefficient of CO
Rearranging Equation 16 gives:
Log [HCO
10
Equation 17
*The equations are from NCCLS standards
Total Carbon Dioxide Content (TCO
TCO (mmol/L) includes both dissolved carbon dioxide and
2
3 -
[HCO ] and is calculated as follows:
TCO = [HCO
2
where PCO
Equation 17.
* The equations are from Reference 2.
[HCO
α(PCO
are measured.
2
3 -
] = pH + log
10
3 -
] + α(PCO )
2
is measured and [HCO
2
2
3 -
]
3 -
]
Equation 16
)
2
in plasma at 37 °C
2
P
CO - 7.604
2
2
.
)*
2
Equation 18
3 -
] is calculated from
Appendix B
B-7