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Anion Gap
Anion gap is the difference between the sum of the sodium
and potassium concentrations (the cations) and the sum of
the chloride and bicarbonate concentrations (the anions),
as follows:
Anion Gap = (Na + K) - (Cl + [HCO
No anion gap is reported if any of the 4 concentrations are
not reported. Any calculated anion gap less than 0.0 mmol/L
is not reported.
References:
1. Mohan, M.S. and Bates, R.G. 1977. Blood pH,
Gases and Electrolytes. NBS Special Publication,
450. U.S. Government Printing Office.
2. National Committee for Clinical Laboratory
Standards. 1999. Tentative Standard for Definitions
of Quantities and Conventions Related to Blood pH
and Gas Analysis. NCCLS 2:10.
3. Williams, W.J., Beutler, E., Ersley, A.J., and Rundles,
R.W. 1977. Hematology. 2nd ed. McGraw-Hill Co.
4. Burtis, Carl A. and Ashwood, Edward R., ed. 1999.
Tietz Textbook of Clinical Chemistry. Philadelphia,
PA: W. B. Saunders Co.
Appendix B
3 -
})
Equation 34
B-15
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