CyBio QuadStack Table of contents Table of contents 1 Basic information ..............................About this manual ............................Intended use ..............................Standards and directives ..........................2 Safety instructions ..............................General ................................Safety markings ..............................Hazard zones and protective devices....................... 2.3.1 Hazard zones ..............................2.3.2 Protective devices .............................
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Table of contents CyBio QuadStack 7 Maintenance and care............................29 Safety instructions ............................29 Maintenance overview ............................. 30 Cleaning the device............................30 8 Transport and storage ............................31 Transport................................31 Storage ................................32 9 Disposal ................................33 10 Spare and wear parts, accessories, consumables ....................34 11 Technical data ..............................
CyBio QuadStack Basic information Basic information About this manual The manual describes the rotating microplate storage CyBio QuadStack with the models: CyBio QuadStack M ¡ ¡ CyBio QuadStack L Depending on the configuration, the microplate storage includes an access module: ¡ Lift Link Module ¡ Lift Turn Lift Module The original manual is written in German.
PCR plates and half-skirted PCR plates with this device. Furthermore, the device is able to handle 96/250 µL, 96/50 µL and 192/60 µL tip boxes provided by the company Analytik Jena in filled or unfilled condition and without lid. 96/1000 µL tip boxes provided by the company Analytik Jena cannot be handled with the device.
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CyBio QuadStack Basic information Furthermore, the following applies in this context: The unfinished machine may only be put into operation if it has been determined that the machine or installation into which the unfinished machine is to be incorporated complies with the provisions of the direc- tive 2006/42/EG and that a corresponding declaration of conformity in accordance with annex II, part 1, section A has been issued.
Safety instructions CyBio QuadStack Safety instructions General For your own safety and to ensure error-free and safe operation of the device, please read this chapter carefully before commissioning. Screen Observe all safety instructions listed in these instructions, as well as all messages and in- structions displayed by the control and analysis software on the monitor.
CyBio QuadStack Safety instructions Warning symbol Meaning Comment Warning of crushing On all stacker shafts, on the access module: Warning of hand injuries caused by moving device components Warning: automatic start On all stacker shafts: Warning of auto- matically rotating stacker shaft during ongoing processes Crushing injuries warn- Risk of irreversible hand injuries due to...
Safety instructions CyBio QuadStack Fig. 2 Hazard zones 1 Range of rotation of the stacker shaft 2 Passage area of the transport system 3 Range of movement of the access module Warning labels ¡ Never use the device without its protective housing. ¡...
CyBio QuadStack Safety instructions 2.3.2 Protective devices Fig. 3 STOP button Press the STOP button (1 - see figure) to bring all drives to an immediate stop. Requirements for the operating personnel The device may only be operated by trained specialist personnel instructed in technical safety.
Safety instructions CyBio QuadStack Only operate the device when connected to a power socket with grounding conductor. The grounding conductor must not be interrupted (e.g., when using a voltage regulating transformer). Only use extension cables equipped with grounding conductors! When replacing the power cable, ensure that the new power cable has the proper di- mensions for the intended operating voltage (see technical data).
Technical description CyBio QuadStack Technical description Design The compact and flexible microplate storage has a 4-fold stacker shaft. The stacker shaft is used to hold, pick up and dispense various types of labware. Fig. 4 Device configuration 1 Rotating 4-fold stacker shaft 2 Stack door 3 Bottom plate 4 Protective housing with door...
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Technical description Furthermore, the device is able to handle 96/250 µL, 96/50 µL and 192/60 µL tip boxes provided by the company Analytik Jena in filled or unfilled condition and without lid. 96/1000 µL tip boxes provided by the company Analytik Jena cannot be handled with the device.
CyBio QuadStack Technical description Control elements Fig. 6 Control unit 1 Button - 2 STOP button Clockwise rotation 3 Button - 4 LED – Counter-clockwise rotation Operating status display Operating status display The device front houses the control panel with an operating status display. This indi- cates the current operating status of the device: Display Operating status...
Technical description CyBio QuadStack Access modules The access module serves the following purposes: Placing labware into the stacker shafts ¡ Removing labware from the stacker shafts ¡ Transferring labware to another transport device such as a robot ¡ ¡ Rotating the labware (Lift Turn Lift Module only) Electromagnetically controlled latches retain the microplates inside the stacker shafts.
CyBio QuadStack Technical description Fig. 8 Lift Link Module 1 Lifter 2 Housing 3 Interface (on the rear) The access module lifts the labware out of the transport system and loads the stacker shafts via the lower stacker shaft opening. The lifter places the labware inside the shaft onto the electromagnetic latches.
The labware can be taken out of the access module by the gripper of a laboratory robot such as CyBio Carry, for example. Fig. 10 CyBio QuadStack in an installation with Analytik Jena devices Type plate Type plates are located on the terminal strip of the device as well as on the back of the access module.
CyBio QuadStack Installation and commissioning Installation and commissioning Location requirements Installation conditions The operating room must meet the following climatic conditions: ¡ Temperature range: +15 to +35 °C ¡ Allowable relative humidity: ≤75 % (30 °C), non-condensing For pipettor site selection, the following rules should be observed: ¡...
Installation and commissioning CyBio QuadStack Re-commissioning The operator may put the device back into service after an unforeseeable device failure. Before doing this, make sure that it is safe to put the device back into service. Please re- fer to the section “Safety instructions” for further information. When the device displays error messages, please refer to the instructions in the chapter “Troubleshooting”.
CyBio QuadStack Operation Operation Switching on CAUTION Risk of crushing at automatic start-up There is a risk of crushing fingers and hands within the device’s range of movement. ¡ Do not reach into the device with your hands or any type of object during initializa- tion and after starting the control software.
¡ Do not reach into the device with your hands or any type of object during initializa- tion and after starting the control software. In normal operation, the device is operated using a Analytik Jena control software. How- ever, limited manual operation via the operating unit is possible, for example, for load- ing microplates or for eliminating faults.
CyBio QuadStack Operation Manually loading the device } Verify that the status indicator is green meaning that all running processes have been completed. } Use the ← or → buttons to rotate the stacker shaft until the desired shaft is accessi- ble.
Operation CyBio QuadStack If you wish to insert microplates in the opposite direction (rotated by 180°), turn the small magnetic plate to indicate that the orientation from A1 has changed. Inserting CyBio Tip Box Make sure to insert the tip box in the correct direction. The green “OK” sticker must be pointing at you.
CyBio QuadStack Troubleshooting Troubleshooting General information on troubleshooting NOTICE Error messages on the device (indication on the control PC) inform the user about the cause and possible remedy. Malfunctions are usually reported: by the control software ¡ ¡ by the status LED on the control panel (red) If malfunctions are obviously caused by the operator, work with the device may be re- sumed after eliminating the fault.
Troubleshooting CyBio QuadStack Simple fault that can be corrected Serious fault immediately Steps Follow the instructions of the Switch of the device’s mains ¡ ¡ device program. switch and unplug the power Fix the condition causing the cord from the mains socket. ¡...
CyBio QuadStack Maintenance and care Maintenance and care Safety instructions NOTICE Important information! Before starting any work, read the instructions in the main “Safety instructions” chapter. DANGER Touching live components may result in serious injury or death! Switch off the devices and disconnect the power cables from the mains socket before all maintenance and servicing work! Secure the devices against unintentional reactivation! The operator is prohibited from carrying out maintenance and servicing work on live de-...
Maintenance and care CyBio QuadStack Maintenance overview Maintenance interval Maintenance task Weekly ¡ Clean the device. Annually ¡ Check the electrical connections for tight fit. ¡ Check the fastening screws of all moving components for tight fit. Have the electrical components and cables, including the PE ¡...
CyBio QuadStack Transport and storage Transport and storage Transport NOTICE The transport is carried out by the manufacturer' s service or by the service partners au- thorized by the manufacturer. CAUTION Material damage to the device or components! Environmental influences, impact and condensation can destroy individual components! Protect all components of the device against environmental stresses, impacts and con- densation during transport by taking appropriate measures! Intermediate storage of the device outdoors is not permitted!
Transport and storage CyBio QuadStack Never lift the device by the protective housing. ¡ Fig. 14 Transporting the device Storage NOTICE Risk of device damage due to environmental conditions Environmental influences and condensation can destroy individual components of the device. ¡ Only store the device in air-conditioned rooms. ¡...
CyBio QuadStack Disposal Disposal At the end of its useful life, the device or its components must be disposed of in ac- cordance with the legal regulations. The responsibility rests with the owner of the device.
Spare and wear parts, accessories, consumables CyBio QuadStack Spare and wear parts, accessories, consumables NOTICE The device, accessories and consumables are aligned with each other by the manu- facturer. Damage or malfunction when using other than the specified components ¡ Only use the components recommended by the manufacturer ¡...
Microplates in ANSI/SLAS format, including deep-well and rigid full-skirted PCR plates No flexible full-skirted or half-skirted PCR ¡ plates Tip boxes provided by the company ¡ Analytik Jena 96/250 µL, 96/50 µL, 192/60 µL no 96/1000 µL tip boxes ¡ Process control Control software CyBio Composer; CyBio Scheduler as well as software compatible with ActiveX + .Net...
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Technical data CyBio QuadStack Ambient conditions Temperature during operation +15 to +35 °C Humidity during operation ≤75 % (30 °C), non-condensing Maximum altitude 2000 m Temperature and humidity during stor- -10 to +50 °C, ≤85 % (30 °C) Installation location Stable, horizontal, dry, free from vibration...
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Fig. 8 Lift Link Module ..............................19 Fig. 9 Lift Turn Lift Module ............................19 Fig. 10 CyBio QuadStack in an installation with Analytik Jena devices ................. 20 Fig. 11 Control unit................................24 Fig. 12 Inserting microplates ............................25 Fig. 13 CyBio Tip Box with “OK”...
Glossary CyBio QuadStack Glossary ANSI/SLAS Standard created by the "Society for Laboratory Au- tomation and Screening”. Here, normally reference is made to the standards (formerly SBS standards) for the standardization of Labware dimensions. Footprint: 127.76 x 85.48 mm (±0.5 mm); Source: https://www.slas.org/education/ansi-slas-mi- croplate-standards/ ESTOP ESTOP is a safety function.
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