Page 1 Ver. 2020.09.10.04...
Page 2: Safety Precautions
Safety Precautions Before use WARNINGS and CAUTIONS stated below are intended to ensure safe operation, please follow them carefully. SAFETY INSTRUCTIONS CAUTIONS 1. Read Instructions – All the safety and operating instructions should be read before operating the instrument. 2. Keep the Instructions – Please keep the safety and operating instruction manual for future Risk Of Electric Shock Do Not Open reference.
Page 3: Specification
Detection wavelength: 260nm, 280nm,320nm. Display Screen: 7 inch colored touch panel . 10. Accessories: T - Rack, Cartridge Rack . 11. Barcode Scanner(MagCore HF16 Plus optional), embedded thermal printer. (MagCore Super only) Power Supply Voltage: AC 100V~ 240V; Frequency: 50/60Hz Dimension W760 x D710 x H770 (mm) / W27.95 x D29.92 x H30.31 (inches)
Page 4: Table Of Contents
CONTENTS Safety Precautions ............1 Specification .
Page 5 Replace optic lamp power supply ..........Replace the pistons .
Page 6: Accessories
Sample Tube /Elution Tube X 20 Pipette Tip X 20 10. MagCore Cuvette Set(10pcs) X 1 11. Waste Box X 1 (MagCore Super Only) (MagCore HF16 Optional) 12. Barcode Scanner X 1 (MagCore Super Only) You can purchase Cat. No.: MSC100 MagCore Cuvette Set (X100) from the...
Page 7: Installation
Installation ━ Before Installation Please refer to the machine size shown in the above figure to prepare an appropriate position for the machine and reserve space for heat dissipation. RBCBioscience...
Page 8: Iq/Oq/Pq Documents
IQ/OQ/PQ Documents ━ IQ Documents...
Page 9: Oq Documents
━ OQ Documents RBCBioscience...
Page 10: Pq Documents
━ PQ Documents...
Page 11: System Overview
System Overview Slots There are a total of 16 slots (number 1~16 from left to right) RBCBioscience...
Page 12: Module Position Description
━Module Position Description Liquid handling module Frame Gantry structure Work platform Optic module (Super Only) Heating module...
Page 13: Unpacking
Unpacking If the cargo is damaged, White If the cargo is upside down, Sliver Prepare Unpacking Tools 1 . Hex Wrench (3mm) 2. Phillips Screwdriver 3. Scissors RBCBioscience...
Page 14: Install Magcore® Hf16 Plus/Super
Install MagCore® HF16 Plus/Super Proceed installation procedures after placing the instrument on a solid bench-top. 1.Use screw drivers to loosen the screws as shown in the picture. 2.Remove the fixing plates. 3.Save all the materials for maintenance for future use.
Page 15: Installation Settings And Test
━ Installation settings and test Step 1. Please set up the local time. Please refer to System Status chapter for the information about the operation. (Please refer to P .28) Step 2. Test piston Please refer to Piston Test chapter for the information about the operation.
Page 16: Touch Panel And User Interface
Optics Barcode scanning, Optics data browsing and editing, printing output functions functions (MagCore Super only) (optional for MagCore HF16 Plus) MagCore® Super / HF16 Plus provides 7-inch full-color touch panel and easy-to-use user interface. The operation screen will show the current status, ending time and test report of the machine.
Page 17: Install Magcore® Cuvette
━ Install MagCore® Cuvette ━ Install reagent cartridge (MagCore Super Only / for optic test) When installing it, please do not scratch the optic test window. 1. Please put MagCore® Cuvette into the Please insert the front end of the cartridge into the space corresponding sample's well.
Page 18: Emergency Stop
━ Emergency Stop Please read the security information to correctly stop the machine when an accident takes place. When an emergency situation occurs and the machine is still running, please press the stop button or open the door of the machine to stop the machine immediately.
Page 19: Start Programs
If there is no barcode record, the system will not ask you. (MagCore Super only; optional for HF16 Plus) Select Elution Buffer. (Only for tissue kit.) RBCBioscience...
Page 20: If The Test Result Of The Optic Measurement Is Over Detection
(MagCore Super Only) Select to enable or disable the optic measurement function. (MagCore Super Only) ( 201, 202, 211, 105 without the function) A.Please record and save the current measured data. Please confirm the parameters and press the Start button to execute the program.
Page 21 B.Prepare to dilute C. Record and save the measured values. 1. Please take out the eluates which do not need to be diluted. 1. Insert the USB Flash Drive and then 2. Please put a new 200μl SP Tip in the press the Save button to save the W4 corresponding to the sample to current measured values after the USB...
Page 22: Stop
━ Enable the barcode function ━ Stop (MagCore HF16 Plus Only) The barcode function of MagCore HF16 Plus is not During the test process, please press the Stop enabled by default. If you already purchased the button if you want to pause. barcode scanner, you have to enable the scanner function.
Page 23: Barcode Scanning And Editing
━ Optic data ━ Barcode scanning and editing (MagCore Super Only) (optional for MagCore HF16) Please select the Optics Data button in the main menu. Please select the Barcode button in the main menu. [ Barcode main menu] [ Optics Data main menu ] The machine will automatically save two batches of Delete all saved barcodes.
Page 24: Easy Maintenance
Easy maintenance Easy maintenance includes the maintenances which need to be done by users. These items include sterilization, clearing, simple test and error message report, etc. Users must perform these items periodically to ensure the system is functioning properly. ━ Replace O-Ring ━...
Page 25 W1 of the T-Rack. 3. Please select the Test W2 Tip. C. Test the Tip of the W4. (MagCore Super Only) 1. Please put the 200μl SP Tip into W4 of T-Rack. 2. Please add 1 ml water to the Sample Tube and put it in W1 of the T-Rack.
Page 26: Clean Piercing Needles
━ Clean Piercing Needles ━ Reject Tip If the system is stopped from power shortage or other abnormal conditions and the tips are still on the pistons, you have to press Reject Tip to remove the tips from the pistons. Please select Piercing Needles.
Page 27: Heater Test
━ Heater Test ━ Optic Test (MagCore Super Only) Before testing the heater, please add 500μl water Please put the cuvette into the cartridge rack into the heat block well 1 (as shown by the arrow) before the optic test without any liquid and not the of the cartridge, and then put the cartridge into 200μl SP tip.
Page 28: Uv Sterilization
━ Alarm History ━ UV sterilization If the machine is not functioning properly or if the following messages appears, the engineers may ask you to download the error records for them to diagnose the machine. Please select the UV button. Please select the sterilization time.
Page 29: System Status
Program Ver. : Program version PLC Ver. : PLC version Optic module version Optics Ver. : (MagCore Super Only) Optical module serial number Optics Serial : (MagCore Super Only) The total time that the Power on Time : machine is powered on...
Page 30: Update Program
━ Update Program ━ Clean the Waste Box You can use the USB to update the system. Please download and place a copy of the program in the root directory of the USB Flash Drive. Then insert the USB Flash Drive into the USB Port of the Please remove the waste when the program is machine.
Page 31: Replace Thermal Paper
━ Replace thermal paper ━ Replace fuse 250V 5A Please use the specific fuse. If you use the fuse with higher specification, the machine may be burned. Open the cover of the printer and take out the thermal paper roll when the thermal paper runs out.
Page 32: Advanced Maintenance
Advanced maintenance Advanced maintenance includes system maintenance, component replacement and advanced machine calibration. Only trained engineers can perform the above operations. Recommended frequency for maintenance Frequency of use Maintenance cycle Less than 20 times a month 1 Year 1 to 3 times daily Six months More than 3 times a day Three months...
Page 33 Caution ! Turn off the power and remove power socket before processing advanced maintenance ! Caution ! All advanced maintanence must be performed by trained Engineers ! RBCBioscience...
Page 34: Disassemble The Back Service Lid
Disassemble the back service lid...
Page 35: Disassemble The Top Service Lid
Disassemble the top service lid RBCBioscience...
Page 36: Axis Directions
Axis directions Y-axis direction X-axis direction V-axis direction C-axis direction M-axis direction...
Page 37: Replace The Uv Lamp
Replace the UV lamp Open the front door. 1. Switch off the power supply. 2. Loosen the three screws of the protection metal sheet (4mm Hex wrench), and take off the sheet. 3. Replace the lamp and lock back all the parts. RBCBioscience...
Page 38: Replace Led Light
Replace LED Light Open the front door. 1. Unplug the wire connector of the LED. 2. Loosen the three or five screws on the top of the piston module (3 mm Hex wrench), and take off the LED module. 3. Replace the LED light bar and lock back all the parts.
Page 39: Replace The Optic Lamp
Replace the optic lamp (MagCore® Super Only) 2. Loosen four 1. Loosen four 2. Loosen four screws screws of optic on optic service lid screws of back 1.Open the back service lid service lid service lid 2. Cut cable tie (6 places) 1.Disconnect the connector 3.
Page 40: Replace Optic Lamp Power Supply
Replace optic lamp power supply 1. Open back and top service lead. 2. Remove 2 leads from the rack. Unscrew 4 screws on each lead, lift them and remove to make cable tray visible. 3. Push the lamp module aside to make sure the top of the cable tray is exposed. Use tools to remove connecting part on top of the tray until it is completely opened and cables can be easily removed.
Page 41: Replace The Pistons
Replace the pistons Open the front door. 1. Unplug the wire connector of the LED. 2. Loosen the three screws on the top of piston module (3mm Hex wrench), and take off the LED module. 3. Screw off the eight screws on the acrylic nameplate at the front side (2.5mm Hex wrench).
Page 42 5. Press the V-axis downward until the tool can be put into the holes above the pistons. 6. Screw off the four screws (2.5mm Hex wrench). 7. Disassemble the fault pistons and replace with new pistons (2.5mm Hex wrench). 8. Screw up the four screws (2.5mm Hex wrench). 9.
Page 43: Replace The Ejector Rod Module
Replace the ejector rod module. Open the front door. 1. Unplug the wire connector of the LED. 2. Loosen the three screws on the top of piston module (2.5mm Hex wrench). 3. Screw off the eight screws on the acrylic nameplate at the front side (3mm Hex wrench), and take off the LED module.
Page 44: Replace The Heater Module
Replace the heater module Open the front door and take out the waste box, cartridge rack and T-rack. 1. Screw off the four screws on the heating module (2 mm Hex wrench). 2. Pull out the temperature probe from the module. 3.
Page 45: Replace The Gas Spring On The Front Door
Replace the gas spring on the front door 1. Open the front door. 2. Screw off one screw and one nut (4mm Hex wrench) (Note that you can only replace one gas spring at a time). 3. Screw off the screw on the front door (3mm Hex wrench). 4.
Page 46: Replace Door Sensor
Replace Door Sensor 3.Disconnect the connector 1.Open the front door 2.Pull out the sensor...
Page 47: Replace The M-Axis Sensors
Replace the M-axis sensors Open the front door and take out the waste box, cartridge rack and T-rack. 1. Screw off the two screws on each sensor.(2.5mm Hex wrench). 2. Remove the wires connected to the sensors. 3. Replace new sensors and screw up the screws. RBCBioscience...
Page 48: Replace The Sensors Of C, V, X And Y Axes
Replace the sensors of C, V, X and Y axes 1. Remove the wires connected to the sensors. 2. Screw off the two screws on each sensor(2.5mm Hex wrench). 3. Replace the sensors and lock back all the parts.
Page 49: Replace Cooling Fans
Replace Cooling Fans 3. Loosen two screws and remove protecting RBCBioscience...
Page 50: Replace The X-Axis Stepper Motor
Replace the X-axis stepper motor Open the back service lid. 1. Unplug the connector to the X-axis motor. 2. Screw off the two screws on the holder of the motor (5mm Hex wrench). 3. Screw off the two screws on the timing gear (1.5mm Hex wrench). 4.
Page 51: Replace The Y-Axis Motor
Replace the Y-axis motor Open the back service lid. 1. Install the Y-axis fixing plate on the machine and screw up the two screws. (Phillips screwdrivers). 2. Unplug the connector of the Y-axis motor. 3. Screw off the four screws on the metal sheet of the Y-axis motor (3mm Hex wrench). 4.
Page 52: Replace The Y-Axis Belt
Replace the Y-axis belt Open the back service lid. 1. Install the Y-axis fixing plate on the machine and screw up the two screws (Phillips screwdriver). 2. Screw off the four screws of the metal sheet of the Y-axis motor (3mm Hex wrench). 3.
Page 53: Replace The V-Axis Motor
Replace the V-axis motor Open the front door. 1. Unplug the wire connector of the LED. 2. Loosen the three screws on the top of piston module (2.5mm Hex wrench), and take off the LED module. 3. Screw off the eight screws on the acrylic nameplate at the front side (2.5mm Hex wrench).
Page 54 5. Unplug the connection wire to the V-axis motor. 6. Screw off the four screws on the motor (3mm Hex wrench). 7. Screw off the three screws on the axle sleeve (2.5mm Hex wrench). 8. Replace a new V-axis motor. 9.
Page 55: Replace The C-Axis Motor
Replace the C-axis motor Open the back service lid. 1. Unplug the connector wires to the C-axis motor. 2. Screw off the four screws on the optic lamp driver (3mm Hex wrench). 3. Screw off the two screws on the driven timing gear (4mm Hex wrench). 4.
Page 56: Replace The C-Axis Timing Belt
Replace the C-axis timing belt Open the back service lid. 1. Unplug the connector to the optic lamp driver. 2. Screw off the four screws on the optic lamp driver (3mm Hex wrench). 3. Screw off the two screws on the driven timing gear (4mm, 5mm Hex wrench). 4.
Page 57: Replace The Lift Motor Of The Base
Replace the lift motor of the base Open the front door and take out the waste box, cartridge rack and T-rack. 1. Unplug the power connector to the lift motor. 2. Screw off the six screws on the liquid container above the heating module (2mm Hex wrench).
Page 58: Replace The Timing Belt Of The Lift Motor Of The Base
Replace the timing belt of the lift motor of the base Open the front cover and take out the waste box, cartridge rack and T-rack. 1. Unplug the power connector to the lift motor. 2. Screw off the six screws on the liquid container above the heating module (2mm Hex wrench).
Page 59: Replace Pcb
Replace PCB Power Switch 1. Loosen four screws of service lid 3. Loosen five screws of PCB 2. Disconnect the connector of PCB RBCBioscience...
Page 60: Replace Plc
Replace PLC 1. Loosen four screws on top service lid 2. Disconnect the connector of PLC 3. Loosen two fixed screws of PLC...
Page 61: Replace Power Supply
Replace Power Supply 1. Loosen four screws on top service lid 3. Loosen four screws of power 4. Loosen four screws 2. Disconnect the connector of power RBCBioscience...
Page 62: Replace Touch Panel
Replace Touch Panel 1. Open the front door 4.Remove the 3.Remove fixed block 2.Loosen two screws...
Page 63: Replace Printer
Replace Printer 1. Open the front door 3.Close the front door 2.Loosen four screws 4.Open the cover 6. Loosen three screws 5. Take off the paper roll RBCBioscience...
Page 64: Electrical Control And Engineering Software
Electrical control and engineering software...
Page 65: System
System (Human–Machine Interface) Select Program [ Cartridge Code ] HMI send the program to PLC PLC : Programmable Logic Controller PLC runs programs, actions, and send a signal through PCB to all parts Main_Board For Example: Optic Spectrometer : Win8 Program : App : CPU RBCBioscience...
Page 66: Parts
Parts Printer Door X Home Y Home Barcode Down V Home Optic Spectrometer C Home M Axis ( Heater and Magnet ) D2 Lamp Up Down UV Lamp Temperature sensing rod Y Axis V Axis X Axis C Axis Heater DC 24V Power Supply Power Switch Power Cable...
Page 67: Main Board Configuration
Main board configuration There are 2 types of PCBs in MagCore Super: Old type and New type. Please check your PCB type and refer to the corresponding configuration. Old Type RBCBioscience...
Page 68: Plc Configuration
New Type PLC configuration...
Page 69: Copy The Engineering Software To The Desktop
Copy the engineering 5. Select a destination folder. software to the desktop 1. Copy the engineering software “SHF16 Install Tool Software” to the desktop. 2. Open the folder and select “EasyDownload_ v1.83” (for updating PLC). 3. Open the folder and select “PM_2.0.5.11” (for updating HMI).
Page 70: Create An Uploading Folder
Create an uploading folder 5. Confirm the transmission parameter and press ”Finish”. 1. Select the icon of PM Designer at the folder or desktop. 6. Confirm that the new project has been created. 2. Select New in the File to create new data. 3.
Page 71: Install The Driver
Install the driver 5. Select “Update Driver” at the “General” subpage. 1. Connect HMI to the computer by a transmission wire . 2. If the driver fails to be installed successfully, please enter the “Control Panel” to modify the settings. 6.
Page 72 8. Find the “V2.0” folder at the sub-folder, “PM Designer”, and select “Usb” folder at the “V2.0” folder and press “Confirm”. 9. Select "Trust the source of the software" and install it. 10. The update is finished.
Page 73: Hmi Updating
HMI updating 5. Select a connection mode. A Male - B Male USB Cable 6. Start to begin the upload and finish the updating. 1. Connect HMI to the computer by a USB transmission wire. 2. Start the PM Designer software. 3.
Page 74: Plc Updating
3. Change the switch of the PLC from “Run” to PLC updating “Stop”, and replace the connection wire with the PLC-RS232 communication connection 1. Turn off the power supply of the machine. wire. Switch “ RUN “ to “ STOP 2.
Page 75 7. Select to write DVZ into PLC and click Next. 10. Select a communication method and click “Download” to start the download. 8. Select a DVZ file to be uploaded and press Next. Click the “ PLC-xxxx.dvz “ File and Click the “ Open “ 9.
Page 76 12. Power OFF 13. Reconnect the original connection wire and change the switch to “Run” to finish the installation. Switch “ STOP “ to “ RUN Disconnect “PLC RS232 Cable “and change to original Cable“ 14. Power ON...
Page 77: Position Teaching Tools
Position Teaching Tools 200 µl SP Tip Pipette Tip tool A tool B tool C RBCBioscience...
Page 78: The Pre-Operation Before Calibration
The pre-operation before 4. The wiring configuration on the connector of the motor on the main board. calibration 1. Select Maintenance. 2. Select Vender and input password. Disconnect X ,Y , C Motor Power Cable 3. Select Teach Position and enter the teaching page.
Page 79: X-Axis Calibration
X-axis calibration 1. Remove the connectors to the X-axis, Y-axis, and C-axis motors from the main board. (Refer to page 75) 2. Put the 200μl SP Tips at the W4 at the two ends of the T-rack. 3. Move the X-axis and Y-axis to the position where the 200μl SP Tip is located. Move the piston to align with the tip.
Page 80 4. Select “Input X Pulse” and input the X Encoder value shown at the top side, and then select “Load X Encode Calculate”. Input new value (pulse) Press the “ Load X Encoder Calculate “ 5. Select “Yes” to update the position of the X-axis. 6.
Page 81: Y-Axis Calibration
Y-axis calibration 1. Remove the connectors to the X-axis, Y-axis, and C-axis motors from the main board. (Refer to page 75) 2. Put the Pipette Tips at the W3 at the two ends of the T-rack. (1200 µl) 3. Move the X-axis and Y-axis to the position that the piston take out the Pipette Tip, and press it until the piston completely inserts into the Tip.
Page 82: C-Axis Calibration
C-axis calibration ( Magcore Super Only) 1. Remove the connectors to the X-axis, Y-axis, and C-axis motors from the main board. (Refer to page 75) 2. Select “C Position Page” at the “Teach position” page to enter the C-axis correction page.
Page 83 4. [1] Align tool B with the holes on tool A. [2] Insert tool C to fix the relative position between the tool A and the tool B. Calibrate C1 Position Tool B Insert Tool C Insert Tool C 5. Press “Load C1” and hold for two seconds. Check whether the value of the C Encoder has been written into the C Slot 01 on the right side.
Page 84: Automatic Optical Measurement
Automatic Optical Measurement • The optical module provides O.D. A and A measurement of individual samples. (O.D. detection range: ABS <6.) • A320 Normalization • Disposable cuvettes. RBC Cuvette Deuterium Lamp...
Page 85: Optical Calibration Flow Chart
Optical Calibration Flow Chart Empty Cuvette Test of standard cuvette 1. Place the cuvette into the cartridge rack. When installing it, please do not scratch Make sure the cuvette is placed the optic test window. straight. RBCBioscience...
Page 86: Standard Cuvette Vaule
2. Enter the optic test page and select empty Standard Cuvette Vaule cuvette. S16C001514196 Integration Time : 8 mins Wavelength Value 260mm 10437 280mm 18107 320mm 17475 S16C001614196 Integration Time : 8 mins Wavelength Value 3. Wait for 15 min and press ”Start ”to perform 260mm 10291 the test.
Page 87: Adjust Integration Time
Adjust integration time 1. Enter the vender page, and key in the Wavelength Tolerance password. 260mm ±750 280mm ±1250 320mm ±1250 2. Enter optic parameter page. • If the count values are higher than the range, decrease the integration time by 1 min. •...
Page 88: Start Optical Measurement
Start Optical Measurement (MagCore Super only) 1. Please select the Optics Data button in the 6. After detection, remove the liquid in the main menu. cuvette. Centrifuge briefly and remove the residual liquid. Put 60 μL standard solution into the cuvette. The liquid transfer should be completed within 5 min.
Page 89 RBCBioscience...
Page 90: Trouble Shooting For Alarm Code
Trouble Shooting for Alarm Code Code No. Content Causes and solutions DC Motor Up Time Out [Causes] The motor is not functional or the block plate of the sensor is at the wrong position. [Solutions] (1) Check whether the motor is properly functioning. (2) Check whether the cable dropped off.
Page 91 Code No. Content Causes and solutions Y_Home Sensor Fail [Causes] When performing the motor initial, the Home sensor has no response and the motor collides into a hard stop. [Solutions] (1) Check whether the cable has dropped off. (2) Replace the sensor. V_SoftLimt+ [Causes] Manual V JOG+ operation exceeds the distance programmed...
Page 92 Code No. Content Causes and solutions C_Position Over 60 Pulse [Causes] The position command coordinate is vastly different to the Encoder coordinate. [Solutions] (1) Check whether the terminal of the PLC Y00 Cable has dropped off. (2) Replace the cable connected to the power of the motor. (3) Replace the main board.
Page 93 Code No. Content Causes and solutions X_SoftLimt- [Causes] Manual X JOG- operation exceeds the distance programmed in the software. [Solutions] (1) Alarm Reset (2) Manual X JOG+ operation. X_Encode no change [Causes] No signal response from the Encoder. [Solutions] (1) Replace the cable connected to the Encoder. (2) Replace the motor module.
Page 94 Code No. Content Causes and solutions C_ Motor Hit Hard stop [Causes] When you perform the motor initialization, the motor collides into a hard stop. [Solutions] (1) Check whether the terminal of the PLC Y00 Cable has dropped off. (2) Replace the cable connected to the power of the motor. [Causes] HMI, PLC, or the temperature controller has no response.
Page 95 RBCBioscience...

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Magcore hf16 plus