Thermo Scientific Dionex IonPac AS32-Fast-4mm Analytical Product Manual page 26

5 – Troubleshooting
Observation
Re tention Time Drift
O scillating Re tention
Time
Poor Front End
Re solution
Spurious Pe aks
Analyte Specific
Efficiency Loss
Thermo Scientific
065763-01
Cause
Contaminated sample or
eluent, Poorly mixed eluent
T emperature variability
Poor pump priming or loss of
prime
Inconsistent flow due to
leaking pump
Pump Problems
T emperature variability
Sluggish Injection valve
Incorrect Eluent
Concentration
Column Overloading
Large System Void Volumes
Sample Contaminated
Sluggish Injection Valve
Column Contamination from
sample or system
Product Manual for Dionex IonPac AS32-Fast-4µm Columns
For Research Use Only. Not for use in diagnostic procedures.
Action
Remake Sample/Eluents
Use a thermostatted oven,
check oven operation
Prime Pump
Repair pump
Recalibrate/Repair Pump
Use a thermostatted oven,
check oven operation
Service Valve
Remake Eluents
Reduce Sample Size
Replumb System
Pretreat Samples
Service Valve
Purge contamination, employ a
trap or guard column, clean or
replace column
Reference Section
5.2.1, 5.3.1A, E, 5.3.2A
5.3.1C,D, 5.3.2D, Component
Manual
5.3.1B, 5.3.2B, Component
Manual
5.3.2C, Component Manual
5.3.3A, Component Manual
5.3.3B, Component Manual
5.3.3C, Component Manual
5.2.1, 5.4.4A
B
5.4.4
Component Manual, 5.4.4C
5.5A
5.5B, Component Manual
5.4.2
Page 26 of 42