Beckman Coulter AutoMate 2500 series Reference Manual
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Beckman Coulter AutoMate 2500 series Reference Manual

Beckman Coulter AutoMate 2500 series Reference Manual

Sample processing systems
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See also: Instructions for Use Manual
Reference Manual
AutoMate 2500 Family Reference Manual
B85841D
May 2017
Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821 U.S.A.

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Summary of Contents for Beckman Coulter AutoMate 2500 series

  • Page 1 Reference Manual AutoMate 2500 Family Reference Manual B85841D May 2017 Beckman Coulter, Inc. 250 S. Kraemer Blvd. Brea, CA 92821 U.S.A.
  • Page 2 Trademarks Beckman Coulter, the stylized logo, and the Beckman Coulter product and service marks mentioned herein are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. All other trademarks are the property of their respective owners.

  • Page 3: Table Of Contents

    Contents Revision History, v Safety Notice, vii Introduction, xix CHAPTER 1: System Overview, 1-1 System Features, 1-1 Input and Output Area, 1-1 Base Frame and Rack Types, 1-2 Base Frame Coding, 1-4 Sample Processing, 1-5 Sample ID Processing, 1-5 Overview of Sample Processing, 1-5 Tube Processing, 1-6...
  • Page 4 Contents B85841D...

  • Page 5: Revision History

    Revision History This document applies to the latest software listed and higher versions. When a subsequent software version changes the information in this document, a new issue will be released. Release date Revision Description December 2015 AutoMate software version 4.1.5. Additional operational information moved to the AutoMate 2500 Family Reference Manual from the AutoMate 2500 Family IFU.
  • Page 6 Revision History B85841D...

  • Page 7: Safety Notice

    Safety Notice Read all product manuals and consult with Beckman Coulter-trained personnel before you operate the system. Do not perform any procedure before you carefully read all instructions. Always follow the product labels and the recommendation from the manufacturer. For more information, contact Beckman Coulter.
  • Page 8 Safety Notice Safety Instructions Symbol Meaning Caution This symbol indicates a potential hazard which, if not avoided, could result in minor or moderate injury. Electrical hazard This symbol denotes an area of the system that should under no circumstances be accessed as an electric shock risk exists. Laser radiation This symbol warns that a laser is part of the device.
  • Page 9 Safety Notice Safety Instructions Avoid moving parts While the system is in operation, do not touch or go close to any moving parts. Close protective guards and covers during operation. Failure to close covers correctly can cause injury or incorrect results. Disconnect system from the mains when working on electrical cabinet The electrical cabinet contains live wires even when the main switch is turned off.
  • Page 10 Safety Notice Safety Recommendations Contamination by exceeded fill level Exceeding the maximum fill level can contaminate the device and samples. Use only input and output drawers for loading and unloading tubes While the system is running, only use the input and output drawers to load racks and tubes. Do not reach into the system to manually insert or remove tubes while the system is running! If you need to remove tubes manually, for example in case of an error, stop the system first.
  • Page 11 Customers must understand and follow all laws regarding the correct decontamination and safe disposal of electrical equipment. For Beckman Coulter products bearing this label, contact your dealer or local Beckman Coulter office for details on the take-back program that facilitates the correct collection, treatment, recovery, recycling and safe disposal of these products.
  • Page 12 • Modifications to the system installation or configuration (contact your local Beckman Coulter representative) • Use of accessories or consumables not approved by Beckman Coulter • Operation of the system by untrained staff • Access to the system by untrained staff •...
  • Page 13 Safety Notice Owner's responsibility • Disregard of the warnings and cautions in this manual • Disregard of applicable standards, guidelines and other provisions • Disregard of the service and cleaning instructions in this manual • Do not enable remote access to the AutoMate 2500 Family PC or install any other software! Doing so can disrupt correct operation of the PC and may lead to incorrect patient results.
  • Page 14 Safety Notice Machine Safety Labels Glossary of Symbols Used in AutoMate 2500 Family System Labels Symbol Standard Number And Title Of Title of Symbol And Meaning Of Symbol Standard Symbol Reference Number IEC 60878. Graphical Symbols for Warning; Biological To warn of a electrical equipment in medical Hazard, biological hazard.
  • Page 15 Glossary of Labels Used On AutoMate 2500 Family Systems Label Meaning Of Label Figure Callout Consult the Instructions For Use. The (19) instructions for use can be obtained by contacting your local Beckman Coulter www.beckmancoulter.com/ifu representative obtained electronically at: www.beckmancoulter.com/ifu Caution - risk of injury from moving (1,5) parts.
  • Page 16 Safety Notice Machine Safety Labels Label Meaning Of Label Figure Callout Warning; Biological Hazard. Caution - (2,10-12,17,23) risk of injury from moving parts. Consult the Instructions For Use. Normal working pressure of compressor is 6 bar / 87 psi. www.beckmancoulter.com/ifu 6 bar Do not rotate manually.
  • Page 17 Safety Notice Machine Safety Labels These labels are only present on AutoMate 2500 Family Systems with the optional Recapper module installed. These labels are only present on Automate 1250 and AutoMate 2550 Systems. This label is only present on Automate 1250 and AutoMate 2550 Systems which have been refitted according to MOD 11564: AutoMate 2500 Family Screw Cap Secondary Tubes.
  • Page 18 Safety Notice Machine Safety Labels Figure 2 8 8 8 15 16 18 19 xviii B85841D...

  • Page 19: Introduction

    • Chemists and biologists • Trained laboratory staff All operating staff must be trained to use Beckman Coulter products on behalf of the owner. These persons must be authorized by the owner for the fulfillment of their tasks. The operator is responsible for the user maintenance procedures.
  • Page 20 Introduction EC Declaration by the Manufacturer Laboratory Information System MSDS Material Safety Data Sheets Microtiter Plates Rack ID The bar code identifying the rack, typically a four-digit number Bar code type: "NW-7 with checksum" (also referred to as "Codabar with checksum") Sample Tube containing a specific material like serum, urine or others to perform the tests on...

  • Page 21: System Overview

    Figure 1.1 Input (1) and output (2) areas of the AutoMate system You can use an output drawer as an input drawer to increase sample tube processing to up to 150 tubes per drawer. Contact your Beckman Coulter representative for more information. B85841D...

  • Page 22: Base Frame And Rack Types

    System Overview Base Frame and Rack Types Figure 1.2 Input rack loaded The aliquotter produces secondary containers with bar code labels. These tubes are sorted to the output area. A customizable combination of base frames and racks are located on drawers for automatic and manual workplaces.
  • Page 23 System Overview Base Frame and Rack Types Figure 1.4 Base frame with positioning guides for racks (for example AU NE tray) Figure 1.5 Base frame without positioning guides to be used only with racks (for example 50- position rack) Several standard racks are available: •...

  • Page 24: Base Frame Coding

    System Overview Base Frame Coding Figure 1.6 Input base frame for two 50 position racks, one Centaur tray and two Aero trays MTPs are also an option. Figure 1.7 Microtiter plate A camera captures digital images to identify tube type, cap size, cap color (optional), and sample volume (optional).

  • Page 25: Sample Processing

    System Overview Sample Processing Figure 1.8 Base frame coding Magnets encoding the base frame are located behind this cover. Sample Processing Sample ID Processing Bar code IDs identify sample tubes in the system. Sample tubes that are not labeled with a bar code are automatically placed onto an error rack.

  • Page 26: Tube Processing

    System Overview Sample Processing Tube Processing The tube inspection unit identifies the tube and cap type by shape and color. The volume level is detected and the tube volume is calculated. The system is configured with these parameters used in the lab: —...
  • Page 27 Robot 3 aliquots the sample from the primary to the secondary containers. The aliquot volume of each secondary container is determined by the LIS (or Sorting-Drive A Beckman Coulter representative can change this setting for you. You can print labels with any bar code or no bar code at all.
  • Page 28 After aliquoting, conveyor belt 2 moves the tubes to the pick up position of robot 2. Robot 2 places the tubes on their destination racks. Tubes that require further processing are placed on an input rack. A Beckman Coulter representative can configure the sorting destinations, such as buffer rack or conveyor belt 1.

  • Page 29: Overview Of Sample Processing Steps

    System Overview Sample Processing Overview of Sample Processing Steps Figure 1.9 B85841D...

  • Page 30: Technical Specifications

    System Overview Technical Specifications NOTE If a tube is marked as an error tube, no request is sent to the LIS. The AutoMate system sends the tube to the error rack without further communication. Technical Specifications Technical Specifications: AutoMate 1200/2500 Figure 1.10 Dimensions (from left): Front view, side view without recapper, side view with recapper Figure 1.11 Outline (from left) without recapper, outline with recapper...
  • Page 31 System Overview Technical Specifications Environmental Requirements Table 1.1 Environmental requirements AutoMate 1200 AutoMate 2500 Altitude Must not exceed 2,000 m (6,562 Must not exceed 2,000 m (6,562 ft) Ambient temperature +18°C to +32°C (64°F to 89°F) +18°C to +32°C (64°F to 89°F) Ambient humidity 40 to 80% relative humidity, no 40 to 80% relative humidity, no...

  • Page 32: Technical Specifications: Automate 1250/2550

    System Overview Technical Specifications Table 1.3 Electrical requirements AutoMate 1200 AutoMate 2500 Electrical consumption 360 W (system fully loaded) 480 W (system fully loaded) System current (SC) 1.5 A (system fully loaded) 2.2 A (system fully loaded) Voltage 100-240 VAC [±10%] 100-240 VAC [±10%] Frequency 50 / 60 Hz [±1%]...
  • Page 33 System Overview Technical Specifications Weight Net weight: 720 kg (1,590 lbs) Gross weight: 1040 kg (2,290 lbs) including packaging Environmental Requirements Table 1.4 Environmental requirements AutoMate 1250 AutoMate 2550 Altitude Must not exceed 2,000 m (6,562 ft) Must not exceed 2,000 m (6,562 ft) Ambient temperature +18°C to +32°C (64°F to 89°F) +18°C to +32 °C (64°F to 89°F)

  • Page 34: Throughput And Configuration Specifications

    System Overview Technical Specifications • Flow volume: 50 l/min • Pressure: Maximum 8 bar (116 PSI) Electrical Requirements The line voltage must be free of power surges (overvoltage category II), power changes, and loss of power for the protection of the electronic circuits. Table 1.6 Electrical requirements AutoMate 1250...

  • Page 35: Bar Code Label Format For Primary And Secondary Tubes

    System Overview Technical Specifications AutoMate 1200 AutoMate 1250 AutoMate 2500 AutoMate 2550 Aliquot throughput with 10 % 780 primary and 870 primary and aliquoted to a secondary tube secondary secondary tubes/h tubes/h Input and Output Configuration • Almost unlimited configuration capability of input and output areas, for example drawer width.

  • Page 36: Bar Code Label Design

    40 mm x 30 mm Standard size: 40 mm x 20 mm Optional size: Other sizes may require adjustments to the printer. Contact your Beckman Coulter representative for support. One label roll contains 5,500 labels Bar code label layout You can modify the layout. You can use different layouts for different purposes, such as depending on primary tube information or tube destination.
  • Page 37 System Overview Technical Specifications • Labels are positioned correctly. • Labels are legible, the text is not smudged. 1-17 B85841D...
  • Page 38 System Overview Technical Specifications 1-18 B85841D...

  • Page 39: Run The System

    CHAPTER 2 Run the System Workplace Types Different types of workplaces are available in the system for various purposes. Type Description Input Workplace for sample tubes that enter the system. Distribution Workplace for primary and secondary sample tubes that leave the system. Distribution workplace is the most frequently used type in the system.
  • Page 40 Run the System Microtiter Plates (MTPs) Different well layouts are available. AutoMate 2500 Family systems can process MTPs with the following dimensions. Diameter >=6.3 mm Height <= 22 mm Shape Parallel or nearly parallel sides and rounded or flat bottom B85841D...

  • Page 41: Troubleshooting

    CHAPTER 3 Troubleshooting Recapper: Remove a Parafilm Jam, Replace the Parafilm Roll The IFU instructs you how to remove a Parafilm jam and replace the Parafilm roll. In addition, two series of troubleshooting videos are installed on the AutoMate PC to help you with these tasks.
  • Page 42 Troubleshooting Recapper: Remove a Parafilm Jam, Replace the Parafilm Roll B85841D...

  • Page 43: Appendix A: Automate 2500 Family Documents

    APPENDIX A AutoMate 2500 Family Documents Related Documents Your Beckman Coulter documentation can be found on our website at www.beckmancoulter.com. • AutoMate 2500 Family Instructions for Use • AutoMate 2500 Family Reference Manual • ISB Instructions for Use • Sorting-Drive Client Instructions for Use •...

  • Page 44: Related Documents

    AutoMate 2500 Family Documents Related Documents B85841D...

  • Page 45: Glossary

    AutoMate 2500 Family — Beckman Coulter laboratory automation product line for sorting and aliquoting samples. LIS — Laboratory Information System. Primary tube — The tube that arrives from the customer.
  • Page 46 Glossary Glossary-2 B85841D...

  • Page 47: Index

    Index Base frames Microtiter plates Pipette tips Racks Index-1 B85841D...
  • Page 48 Index Index-2 B85841D...
  • Page 50 © 2017 Beckman Coulter, Inc. All Rights Reserved.

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