Toyota 4runner 2010 Instruction Manual page 307

The defoggers can be operated when
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Vehicles without a smart key system:
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The engine switch is in the "ON" position.
Vehicles with a smart key system:
The "ENGINE START STOP" switch is in IGNITION ON mode.
The back window is completely closed.
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The outside rear view mirror defoggers
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Turning the rear window defogger on will turn the outside rear view mirror
defoggers on.
CAUTION
When the outside rear view mirror defoggers are on
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Do not touch outside surface of the rear view mirrors, as they can become
very hot and burn you.
3-1. Using the air conditioning system and defogger
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