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Thermo Scientific
Fresco 17 / 21 Centrifuge
Instructions for Use
50133376-e • 06 / 2020
Visit us online to register your warranty:
thermofisher.com/labwarranty

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Summary of Contents for ThermoFisher Scientific Fresco 21

  • Page 1 Thermo Scientific Fresco 17 / 21 Centrifuge Instructions for Use 50133376-e • 06 / 2020 Visit us online to register your warranty: thermofisher.com/labwarranty...
  • Page 2 WEEE Conformity This product is subject to the regulations of the EU Waste Electrical & Electronic Equipment (WEEE) Directive 2012/19/EU. It is marked by the following symbol:...
  • Page 3: Table Of Contents

    Accident Prevention .........................iv Precautions ..........................v Chapter 1 Introduction and Description ....................1-1 Characteristics of the Fresco 17 / 21 ................. 1-2 Technical Data ......................1-3 Directives, Standards and Guidelines ..................1-4 Functions and Features ......................1-5 Mains Supply ......................1-5 Rotor Selection ......................
  • Page 4 Shipping and Deposing of Accessories ..............5-6 Chapter 6 Troubleshooting ........................6-1 Mechanical Emergency Door Release ..............6-2 Troubleshooting by User ..................6-3 When to contact Service Technician ................ 6-5 Chemical Compatibility Chart ................A-1 Index ...........................I-1 Fresco 17 / 21 Thermo Scientific...
  • Page 5: Preface

    Failure to follow the instructions and safety information in this instruction manual will result in the expiration of the sellers warranty. Scope of Supply Article number Quantity Check Centrifuge Fresco 17 / 21 Power Supply Cable Rotor 20360104 Allen Wrench 50133376 CD with Instruction Manual If any parts are missing, please contact your nearest Thermo Fisher Scientific representative.
  • Page 6: Intended Use

    WARNING In case of a rotor failure the centrifuge can be damanged. The cooling agent can escape. Ventilate the room well and leave it. Inform Customer Service. Prerequisite for the safe operation of the Fresco 17 / 21 is a work environment in compliance with standards, directives and trade association safety regulations and proper instruction of the user.
  • Page 7: Precautions

    Precautions Precautions In order to ensure safe operation of the Fresco 17 / 21, the following general safety regulations must be followed: • The centrifuge should be operated by trained specialists only. • The centrifuge is to be used for its intended use only.
  • Page 8 Remaining risk: Improper use can cause damages, contamination, and injuries with fatal consequences. • Highly corrosive substances which can cause material damage and impair the mechanical stability of the rotor, should only be centrifuged in corresponding protective tubes. Fresco 17 / 21 Thermo Scientific...
  • Page 9 Introduction and Description Contents “Characteristics of the Fresco 17 / 21” page 1-2 • • “Technical Data” page 1-3 “Directives, Standards and Guidelines” page 1-4 • • “Functions and Features” page 1-5 “Mains Supply” page 1-5 • • “Rotor Selection”...
  • Page 10 The Fresco 17 / 21 is equipped with various safety features: • The housing is made of high-impact resistant plastic and the interior of armour steel.
  • Page 11: Chapter 1 Introduction And Description

    Introduction and Description Technical Data Technical Data The technical data of the Fresco 17 / 21 is listed in the following table. Table 1-1. Technical Data Fresco 17 Feature Value Environmental Conditions -Use in interior Spaces -Altitudes of up to 2,000 m above Sea Level -Max.
  • Page 12: Directives, Standards And Guidelines

    100 V, 50 / 60 Hz IEC 61010-2-020 IEC 61010-2-101 China IEC 61326-2-6 CFDA listed 230 V, 50 / 60 Hz IEC 61326-1 Class B 208-240 V, 50 / 60 Hz EN ISO 14971 EN ISO 13485 Fresco 17 / 21 Thermo Scientific...
  • Page 13: Functions And Features

    Mains Supply The following table contains an overview of the electrical connection data for the der Fresco 17 / 21. This data is to be taken into consideration when selecting the mains connection socket. Table 1-5. Electrical connection data...
  • Page 14: Rotor Selection

    Introduction and Description Rotor Selection Rotor Selection The Fresco 17 / 21 is supplied with a rotor. Various rotors are available to choose from. 24 x 1.5 / 2.0 mL Rotor 75003424 36 x 0.5 mL Rotor 75003436 Dual Row 18 x 2.0 / 0.5 mL Rotor...
  • Page 15 Before Use Contents “Before Setting up” page 2-2 • • “Transporting the Centrifuge” page 2-2 “Location” page 2-2 • • “Aligning the Centrifuge” page 2-3 “Mains Connection” page 2-3 • • “Storage” page 2-4 Fresco 17 / 21 Thermo Scientific...
  • Page 16: Chapter 2 Before Use

    • The supporting structure must be suitable for horizontal setup of the centrifuge. • The centrifuge should not be exposed to heat and strong sunlight. WARNING UV rays reduce the stability of plastics. Do not subject the centrifuge, rotors and plastic accessories to direct sunlight. Fresco 17 / 21 Thermo Scientific...
  • Page 17: Aligning The Centrifuge

    3. Check whether the cable complies with the safety standards of your country. 4. Make sure that the voltage and frequency correspond to the figures on the rating plate. Establish the connection to the power supply with the connecting cable. Fresco 17 / 21 Thermo Scientific...
  • Page 18: Storage

    • Before storing the centrifuge and the accessories it must be cleaned and if necessary disinfected and decontaminated. • Store the centrifuge in a clean, dust-free location. • Be sure to place the centrifuge on its feet. • Avoid direct sunlight. Fresco 17 / 21 Thermo Scientific...
  • Page 19: Control Panel

    Control Panel Contents “Control Panel” page 3-2 • • “Keys” page 3-2 Fresco 17 / 21 Thermo Scientific...
  • Page 20: Keys

    When pressing both arrows the cursor moves to the left. Use the key to change the display mode. (speed / RCF value, sample / Changing the display chamber temperature, run time counter from start or preset speed on) mode Fresco 17 / 21 Thermo Scientific...
  • Page 21: Operation

    4-4 • “Centrifugation” page 4-8 • “Short-term Centrifugation” page 4-8 • “Removing the Rotor” page 4-9 • “Aerosol-tight Rotors” page 4-9 • “Audible Alarm” page 4-9 • “Turning off the Centrifuge” page 4-10 • Fresco 17 / 21 Thermo Scientific...
  • Page 22: Switch On Centrifuge

    1. Close the door by pressing down on it lightly in the middle or on both sides of it. Note The door should audibly click into place. CAUTION Do not slam the door. Rotor Installation The approved rotors for the Fresco 17 / 21 are listed in section “Rotor Selection” page 1-6. Use only the rotors and accessories from this list in the centrifuge.
  • Page 23 4. Thread the fastening tool into the centrifuge spindle clockwise. Hold the rotor with the other hand into position. 5. Close the rotor. 6. Check if the rotor is properly installed by lifting it slightly on the handle. Fresco 17 / 21 Thermo Scientific...
  • Page 24: Entering Parameters

    Press the key to toggle between the two modes. Speed display 2. When the upper indicator is lit the display shows the RCF value. Press the key to toggle between the two modes. RCF display Fresco 17 / 21 Thermo Scientific...
  • Page 25 The maximum RCF value is related to the maximum radius of the tube opening. Remember that this value is reduced depending on the tubes and adapters used. This can be accounted for in the calculation above if required. Fresco 17 / 21 Thermo Scientific...
  • Page 26 If you do not press any key, the display flashes for a few seconds .The new preselected value is now stored and the display shows the actual value. Fresco 17 / 21 Thermo Scientific...
  • Page 27 You can change the settings during the run as follows: 1. Press one of the three keys in the control panel. The current value will switch into the pre-selecting value mode. 2. Enter the new value as described above. Fresco 17 / 21 Thermo Scientific...
  • Page 28: Centrifugation

    Short-term Centrifugation For short-term centrifuging, the Fresco 17 / 21 has a PULSE- function. By holding down the key, spinning will start and continue until the key is let go.
  • Page 29: Removing The Rotor

    By default there is an acoustic signal at the end of any centrifugation run. To switch off this signal proceed as follows: Press the key when you turn on the centrifuge. The display shows: Fresco 17 / 21 Thermo Scientific...
  • Page 30: Turning Off The Centrifuge

    Note The centrifuge is equipped with a special switch for balancing potential voltage discrepancies in the power grid. After pressing the mains switch the display therefore may still flash up to 10 seconds. Fresco 17 / 21 4-10 Thermo Scientific...
  • Page 31: Maintenance And Care

    Maintenance and Care Contents “Cleaning Intervals” page 5-2 • • “Cleaning” page 5-2 “Disinfection” on page 5-4 • • “Decontamination” page 5-5 “Autoclaving” page 5-5 • • “Service of Thermo Fisher Scientific” page 5-6 Fresco 17 / 21 Thermo Scientific...
  • Page 32: Cleaning Intervals

    • After cleaning, treat the entire surface of aluminum parts with corrosion protection oil (70009824). Also treat the cavities with oil. • Store the aluminum parts at room temperature or in a cold-storage room with the cavities pointing down. Fresco 17 / 21 Thermo Scientific...
  • Page 33 1. Pull the centrifuge to the edge of the table. 2. Pull the clip below the sucking grid and remove the filter unit completely by pulling it down. 3. Remove the cumulated dust with a soft cloth. Fresco 17 / 21 Thermo Scientific...
  • Page 34: Disinfection

    10. Dry all of the rotors and accessories after cleaning with a cloth or in a warm air cabinet at a maximum temperature of 50 °C. 11. After cleaning, treat the entire surface of aluminum parts with corrosion protection oil (70009824). Also treat the cavities with oil. Fresco 17 / 21 Thermo Scientific...
  • Page 35: Decontamination

    2. Place the rotor on a flat surface. • Rotors and adapter can be autoclaved at 121 °C. • The maximum permissible autoclave cycle is 20 minutes at 121 °C. Note No chemical additives are permitted in the steam. Fresco 17 / 21 Thermo Scientific...
  • Page 36: Service Of Thermo Fisher Scientific

    This is only valid if the centrifuge has only been mainained by a Thermo Fisher Scientific service technician. Shipping and Deposing of Accessories WARNING Before shipping or deposing centrifuges and accessories you have to clean and if necessary disinfect or decontaminate everything. Fresco 17 / 21 Thermo Scientific...
  • Page 37: Troubleshooting

    Troubleshooting Contents “Mechanical Emergency Door Release” page 6-2 • • “Troubleshooting by User” page 6-3 “When to contact Service Technician” page 6-5 • Fresco 17 / 21 Thermo Scientific...
  • Page 38: Mechanical Emergency Door Release

    5. Remove the wire from the hole and open the centrifuge door. Now you can remove your samples. Emergency Door Release Figure 6-1. Emergency Door Release Reconnect the centrifuge once the power has been restored. Switch on the centrifuge. Fresco 17 / 21 Thermo Scientific...
  • Page 39: Troubleshooting By User

    E-01 - E-13 Rotor stops with deceleration to standstill. Internal program error The centrifuge cannot be operated. Switch the instrument off and on again. If an error message appears again, inform Customer Service. Fresco 17 / 21 Thermo Scientific...
  • Page 40 E-36 Rotor stops with deceleration to standstill. Overcurrent or error in current measurement The centrifuge cannot be operated. Switch the instrument off and on again. If an error message appears again, inform Customer Service. Fresco 17 / 21 Thermo Scientific...
  • Page 41: When To Contact Service Technician

    NV-RAM number EEPRO NV-RAM version Cycle counter CYCLE • The values shown above are just examples. Software 0583 Version 01 NV-RAM 4521 Version 01 cycles completed 2. Communicate the software version to the service technician. Fresco 17 / 21 Thermo Scientific...
  • Page 42   Troubleshooting Fresco 17 / 21 Thermo Scientific...
  • Page 43: Chemical Compatibility Chart

    S S U U S U M U S U U S U U U M U M U U U S U U S U S U U - M M - S U U U U U U U - M S M - Benzyl Alcohol Fresco 17 / 21 Thermo Scientific...
  • Page 44 S S S U S U S S S U Ethylene Oxide Vapor M S S - S S S - S S S S - S S - S S S S S S S M S S S Ficoll-Hypaque Fresco 17 / 21 Thermo Scientific...
  • Page 45 U U U U M S S U S U U S U U U U U M U U U S S M U S U Methylene Chloride S S U U S S M S S U U S U S U U U S S U U S S S S U U Methyl Ethyl Ketone Fresco 17 / 21 Thermo Scientific...
  • Page 46 U S M U S S U U U U Pyridine (50 %) M S S - S S S - S S S S S S S - S S S S S S M S S S Rubidium Bromide Fresco 17 / 21 Thermo Scientific...
  • Page 47 S S S S S S S S S S S S S S S S S S S S S S S Citric Acid (10 %) M S S M S S M S S S S S S S S S M S S S S S S S S S S Polyethyleneterephthalate Fresco 17 / 21 Thermo Scientific...
  • Page 48 Performance unknown; suggest testing, using sample to avoid loss of valuable material. Chemical resistance data is included only as a guide to product use. No organized chemical resistance data exists for materials under the stress of centrifugation. When in doubt we recommend pretesting sample lots. Fresco 17 / 21 Thermo Scientific...
  • Page 49: Index

    ........... iii Scope of Supply ............1-5 Features ..............5-6 Service ............5-3 Filter Unit ..........6-5 Service Technician ............1-5 Functions ............2-2 Setting up ............5-6 Shipping ............1-4 Standards .............2-4 Storage ............1-4 Guidelines ............4-2 Switch on Fresco 17 / 21 Thermo Scientific...
  • Page 50 Index: ..........1-3 Technical Data ............. 2-2 Transporting .........6-1, 6-3 Troubleshooting ............. 4-10 Turning off Fresco 17 / 21 Thermo Scientific...
  • Page 52 Thermo Electron LED GmbH Zweigniederlassung Osterode Am Kalkberg, 37520 Osterode am Harz Germany thermofisher.com/centrifuge © 2011-2020 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries unless otherwise indicated. Delrin, TEFLON, and Viton are registered trademarks of DuPont. Noryl is a registered trademark of SABIC. POLYCLEAR is a registered trademark of Hongye CO., Ltd.

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