Upgrade Overview - abi PRISM 377 User Manual

Upgrade Overview

Product Overview
The ABI P
the capabilities of the 377 DNA sequencer to support up to 96 lanes for
both Sequencing and GeneScan applications.
Key Features The following list provides an overview of the key features of the 96-lane
upgrade.
Hardware The following hardware is required to upgrade to 96-lane capability.
Required
1-2 Introduction
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®
377 DNA Sequencer 96-lane Upgrade Kit enhances
RISM
Increased scan window by 20%, allowing additional lanes to be
added without losing sensitivity or increasing scan time
Increased number of data collection to 480 channels, allowing data
collection of three channels plus two-channel separation per lane
Improved Neural Net Tracker, decreasing labor to process gels
Increased comb thickness in loading area to 0.4 mm while using
0.2-mm gel for electrophoresis, causing no change in run time
Improved comb durability and geometry, allowing easier loading of
volumes up to 1.5 µL
Added position-based CCD integration with time scaling, allowing
collection while accelerating the stage, which minimizes noise
Upgraded instruments still run 36-, 48-, and 64-lane gels
ABI P 377-36 or 377XL DNA Sequencer
RISM
Macintosh ® computer with the following specifications
– Power PC processor
– 32 MB RAM (RAM modules supplied if required)
– Mac OS 8 (supplied in kit)