Checking The Solvent Filters; Cleaning The Solvent Filters - Agilent Technologies InfinityLab LC Series User Manual

3 Using the Pump
Prevent Blocking of Solvent Filters

Checking the Solvent Filters

The solvent filters are located on the low-pressure side of the binary pump. A
blocked filter therefore does not necessarily affect the high pressure readings of
the pump. The pressure readings cannot be used to check whether the filters are
blocked or not. If the solvent cabinet is placed on top of the binary pump, the filter
condition can be checked in the following way:
Remove the solvent inlet tube from the inlet port of the solvent selection valve or
the degasser. If the filter is in good condition, the solvent will freely drip out of the
solvent tube (due to hydrostatic pressure). If the solvent filter is partly blocked
only very little solvent will drip out of the solvent tube.
When opening capillary or tube fittings, solvents may leak out.
WAR N IN G
The handling of toxic and hazardous solvents and reagents can carry
health risks.
Observe appropriate safety procedures (for example, wear goggles,

safety gloves and protective clothing) as described in the material
handling and safety data sheet supplied by the solvent vendor,
especially when toxic or hazardous solvents are used.

Cleaning the Solvent Filters

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•
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Never use the system without solvent filter installed.
NOTE
InfinityLab LC Series 1260 Infinity II Binary Pump User Manual
Remove the blocked solvent filter from the bottle-head assembly and place it
in a beaker with concentrated nitric acid (35%) for one hour.
Thoroughly flush the filter with HPLC-grade water (remove all nitric acid,
some capillary columns can be damaged by nitric acid).
Replace the filter.
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