Mixing System; Testing The Static Mixer For Permeability - Thermo Scientific Vanquish VH-P10-A-02 Operating Manual

7 • Maintenance and Service

7.10 Mixing System

7.10.1 Testing the Static Mixer for Permeability

When
Additional items required
Follow these steps
Page 170
Follow the sequence of steps for the maintenance procedure that you
want to perform:
•
To test the static mixer for permeability, see the next section.
•
To replace the static mixer or capillary mixer, see
page 171.
If you observe pressure pulsation, inconstant pressure, or high
backpressure at the column and pump
•
Water as solvent
•
Tissue
1. Disconnect the capillary on the outlet of the static mixer.
2. To absorb liquid leaving the static mixer, place the tissue on the
mixer outlet.
3. Apply a flow of 2 mL/min using water.
4. Observe the pump pressure.
5. Depends on the pressure reading:
♦
Pressure is less than 0.8 MPa
Continue with the next step.
♦
Pressure is 0.8 MPa or higher
Replace the static mixer.
6. Reconnect the capillary to the outlet of the static mixer.
7. Test the pump for leakage (see section 7.12, page
Vanquish Pumps (VH-P10-A-02) Operating Manual
section 7.10.2,
178).