Table of Contents

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Waters Prep Series
Installation and Maintenance Guide
71500045204/Revision B
Copyright © Waters Corporation 2010
All rights reserved

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Summarization of Contents

1 Overview
Waters Prep Series
Details about the Waters Prep Series HPLC systems and their configurations.
Getting Started
Initial steps and procedures for setting up and operating the system.
2 Installing the System
Setting Up and Inspecting
Procedures for unpacking, inspecting, and preparing the system for installation.
Electrical Requirements
Specifications and guidelines for the system's electrical configurations and connections.
Assembling the System
Instructions for connecting major system components, including injectors and modules.
Connecting a Helium Tank
Procedure for connecting a helium tank for solvent sparging in the fluid handling unit.
Setting Up the Plunger Wash
Steps for configuring and connecting the plunger wash system for pump seal lubrication.
Installing Sample Injection Options
Guidance on installing optional sample injection valves and systems.
Installing Columns
Instructions for installing analytical and preparative columns into the system.
Making Detector Connections
Procedures for connecting the column outlet to the system's detectors.
3 Troubleshooting, Testing, and Maintenance
Troubleshooting
Guidance on identifying and resolving common system problems and errors.
Performance Tests
Diagnostic tests to verify system functionality and pinpoint malfunctions.
Maintenance Procedures
Steps for performing routine maintenance on system components.
A Safety Advisories
Warning Symbols
Explanation of hazard symbols and their associated risks for safe operation.
Caution Symbol
Information on the caution symbol, indicating risks of instrument or sample damage.
Electrical and Handling Symbols
Overview of electrical and handling symbols used on instruments and packaging.
B Specifications
Operational Specifications
Key operational parameters, including solvent handling, flow rates, and pressure limits.
Electrical Specifications
Details on power requirements, consumption, fuses, and terminal functions.
Environmental Specifications
Operating and storage conditions for temperature, humidity, and solvent compatibility.
C Spare Parts
Common Parts
List of common spare parts recommended for customer stock and their part numbers.
3725 Injector Parts
Specific spare parts for the Rheodyne 3725i injector, including rebuild kits.
150-mL Configuration Parts
Spare parts specific to the 150-mL system configuration.
D Solvent Considerations
Clean Solvent
Importance of using clean, particle-free solvents for reproducible results and minimal maintenance.
Solvent Miscibility
Guidance on determining solvent miscibility and considerations for changing solvents.
Solvent Degassing
Methods and benefits of degassing solvents to improve chromatography performance.

Table of Contents