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Waters ACQUITY Arc 30-cm Column Heater-Active Overview And Maintenance Manual

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ACQUITY Arc 30-cm Column
Heater-Active
Overview and Maintenance Guide
715004750
Copyright © Waters Corporation 2017
Revision C
All rights reserved

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Summary of Contents for Waters ACQUITY Arc 30-cm Column Heater-Active

  • Page 1 ACQUITY Arc 30-cm Column Heater-Active Overview and Maintenance Guide 715004750 Copyright © Waters Corporation 2017 Revision C All rights reserved...
  • Page 2 This document is believed to be complete and accurate at the time of publication. In no event shall Waters Corporation be liable for incidental or consequential damages in connection with, or arising from, its use. For the most recent revision of this document, consult the Waters website (waters.com).
  • Page 3 Contacting Waters Contact Waters with enhancement requests or technical questions regarding the use, transportation, removal, or disposal of any Waters product. You can reach us via the Internet, telephone, fax, or conventional mail. Waters contact information Contacting medium Information...
  • Page 4 Considerations specific to the 30-cm Column Heater-Active Warning: To prevent burn injuries, set the column temperature to Off, and then allow the column compartment and its components to cool for 60 minutes before touching them. Monitor the column compartment's internal temperature to ensure that all components are cool.
  • Page 5 This guide is intended for use by individuals who operate and maintain the 30-cm Column Heater- Active (CH-30A). Intended use of the CH-30A Waters designed the CH-30A for use in liquid chromatography (LC) applications. The CH-30A is not intended for use with in vitro diagnostic applications. December 5, 2017, 715004750 Rev. C...
  • Page 6 Calibrating To calibrate LC systems, adopt acceptable calibration methods using at least five standards to generate a standard curve. The concentration range for standards must include the entire range of QC samples, typical specimens, and atypical specimens. When calibrating mass spectrometers, consult the calibration section of the operator’s guide for the instrument you are calibrating.
  • Page 7 EC authorized representative Address Waters Corporation Stamford Avenue Altrincham Road Wilmslow SK9 4AX UK Telephone +44-161-946-2400 +44-161-946-2480 Contact Quality manager December 5, 2017, 715004750 Rev. C Page vii...
  • Page 8 Table of contents General information .......................ii Copyright notice ............................. ii Trademarks............................ii Customer comments..........................ii Contacting Waters ..........................iii Safety considerations..........................iii Safety hazard symbol notice ......................iii Considerations specific to the 30-cm Column Heater-Active ............iv FCC radiation emissions notice...................... iv Equipment misuse notice ....................... iv Safety advisories ..........................
  • Page 9 2.4 Controlling the column compartment .................... 53 2.4.1 Specifying the preheater setting ..................53 2.5 Responding to a leak-sensor alarm ....................53 3 Maintenance ......................57 3.1 Contacting Waters Technical Service ..................57 3.2 CH-30A module serial numbers ....................58 3.3 Recommended maintenance schedule..................58 3.3.1 Recommended CH-30A routine maintenance schedule............59 3.4 Spare parts............................
  • Page 10 A.1.1 Specific warnings ........................ 77 A.2 Notices............................78 A.3 Bottles Prohibited symbol ......................78 A.4 Required protection ........................79 A.5 Warnings that apply to all Waters instruments and devices ............79 A.6 Warnings that address the replacing of fuses................83 A.7 Electrical symbols ......................... 85 A.8 Handling symbols ......................... 86 B Specifications......................87...
  • Page 11 Overview The 30-cm Column Heater-Active (CH-30A) is an optional column heating module that manages and maintains column temperature for ACQUITY Arc and ACQUITY Arc Bio systems. A standard, active preheater (APH) device heats incoming solvent before it enters the column. CH-30A modules in Bio systems are equipped with bio-compatible inlet tubing, outlet tubing, and preheaters.
  • Page 12 Figure 1–1: CH-30A module secured to an ACQUITY Arc or ACQUITY Arc Bio system stack Detector CH-30A module ACQUITY Arc Quaternary Solvent Manager-R (QSM-R) or ACQUITY Arc Bio Quaternary Solvent Manager-R (bioQSM-R) ACQUITY Arc Sample Manager Flow Through Needle-R (SM FTN-R) or ACQUITY Arc Bio Sample Manager Flow Through Needle-R (bioSM FTN-R) 1.1 Major components The following figure shows the major components of a CH-30A module.
  • Page 13 Figure 1–2: Front view, door open eCord receptacle Upper-control port location for APH assembly or APH key Column-compartment door Column-compartment trough Drip tray with leak sensor and drain fitting Lower-control port location for APH assembly or APH key December 5, 2017, 715004750 Rev. C Page 13...
  • Page 14 A receptacle on the column heater module receives the column's eCord fob, if one is present. The eCord records column manufacturing and usage data that is accessible from the Waters console. For more information about the recorded column data, see "eCord...
  • Page 15 Figure 1–3: Typical APH assembly Protective cap covering tubing and ferrule Gold, dual-threaded fitting with locking cap nut for connecting to column or column in-line filter APH circuit board Strain-relief sleeve APH-inlet tubing SST sleeve Long, flat compression screw fitting for connecting to sample manager injector Protective cap covering tubing and ferrule 1.3 Column configurations You can install a single chromatographic column of varying sizes within the CH-30A module's...
  • Page 16 many as 50 sample queues run on the column. In regulated environments, the eCord column chip provides documentation of the column used in the validation method. The eCord column chip provides documentation of the column used for each chromatographic run and records the following information: •...
  • Page 17 Preparation and operation Before you prepare a CH-30A module for operation, prepare the sample manager and solvent manager. Before running samples, you must prepare the CH-30A module for operation. To do so, you must perform these tasks: • Install the CH-30A module onto the system stack. •...
  • Page 18 Figure 2–1: System stacks with and without tube guides System stack fitted with tube guides System stack without tube guides Required tools and materials • T20 TORX driver • Integration kit containing the necessary mounting hardware To secure the CH-30A module to a system stack fitted with tube guides: Power-off the sample manager and solvent manager.
  • Page 19 Figure 2–2: Removing the screws from the sample-manager and solvent-manager chassis Top-mounted screw on sample-manager chassis Bottom-mounted screw on solvent-manager chassis Using the two screws that you removed in steps 2 and 3, and two additional M4 × 16 screws from the integration kit, attach the top and bottom adapter brackets to the sample- manager and solvent-manager chassis, oriented as shown in the figure below.
  • Page 20 Figure 2–3: Attaching top and bottom adapter brackets Use M4 × 16 screws (2) from the integration kit here Use the two screws removed in steps 2 and 3 here Using the T20 TORX driver, tighten the screws to secure the brackets. Obtain the proper side-mount shafts from the integration kit to use for an installation that requires the adapter brackets.
  • Page 21 Figure 2–5: Side-mount shaft for installations without adapter brackets Insert each of the two M4 × 50 screws through the two side-mount shafts, from the side with the knurled, side-mount collar. Figure 2–6: Inserting M4 × 50 screw through side-mount shaft M4 ×...
  • Page 22 Figure 2–7: Attaching side-mount shafts to adapter brackets Adapter bracket Side-mount shaft Rotate the knurled collar on the side-mount shafts clockwise until the collar is behind the side-mount shaft face. Figure 2–8: Rotating knurled collar clockwise December 5, 2017, 715004750 Rev. C Page 22...
  • Page 23 Knurled collar Side-mount shaft face 10. Align the two key-hole slots on the CH-30A module with the two side-mount shafts on the adapter brackets. Figure 2–9: Aligning the CH-30A module's key-hole slots with the side-mount shafts Key-hole slots 11. Mount the CH-30A module by sliding its two key-hole slots onto the two side-mount shafts. Warning: To avoid a pinch-point injury, keep fingers away from the side-mount shafts when mounting the CH-30A module.
  • Page 24 Figure 2–10: Rotating knurled side-mount shaft counterclockwise 2.1.2 Installing the column-compartment waste tubing An integrated drip tray fitted with an outlet drain is provided at the bottom of the column compartment. The tray collects and channels to the waste container any leakage that originates inside the compartment.
  • Page 25 Slide one end of the tubing over the barbed portion of the fitting. Cut the opposite end of the tubing to length and connect it to the waste container. Route the tubing, taking care to ensure that liquid can drain through it freely, to the waste container.
  • Page 26 Waste tubing (from stack of system modules) Waste container vent tubing (to fume hood) Waste container 2.1.3 Installing the optional leak sensor The CH-30A module can be fitted with a leak sensor in the integrated drip tray beneath the compartment. Warning: To avoid personal contamination with biologically hazardous or toxic compounds, wear clean, chemical-resistant, powder-free gloves when performing this procedure.
  • Page 27 Figure 2–13: Locating slot in leak-sensor reservoir Slot in leak-sensor reservoir Drip tray Align the leak-sensor T-bar with the slot in the side of the leak-sensor reservoir and slide the leak sensor into place. December 5, 2017, 715004750 Rev. C Page 27...
  • Page 28 Leak-sensor T-bar Leak-sensor cable retainer slot Route the leak-sensor cable through the slot in the leak-sensor cable retainer. Plug the leak-sensor cable connector into the receptacle on the left-hand side of the CH-30A module. Figure 2–14: Connecting the leak-sensor cable Leak-sensor connector receptacle Power-on the sample manager.
  • Page 29 2.2 Connecting the power and signal cable The CH-30A module receives power only from the sample manager. Communications and control signals for the CH-30A module are provided through the 25-pin, D-series, sub-connector (D-sub) on the rear panel of the sample manager. To connect the CH-30A module to the electricity source and operate the CH-30A module, you must plug the D-sub interconnect cable to the mated connectors on the sample manager and CH-30A module, and power-on the sample manager.
  • Page 30 D-sub cable's 25-pin connector on the sample manager's rear panel D-sub cable's 25-pin right-angle connector on the CH-30A module's rear panel Connect the D-sub cable's 25-pin connector to the connector on the sample manager's rear panel. 2.3 Column compartment plumbing connections The standard configuration of the CH-30A module connects a column 30-cm long directly to the sample manager's injection valve via an APH assembly installed in the compartment's lower- control port.
  • Page 31 • SST (stainless steel) tubing and fittings • MP35N (a nickel-cobalt-chromium-molybdenum alloy) tubing for ACQUITY Arc Bio applications • PEEK (polymer-based) tubing and fittings for low-pressure outlet connections to detectors or mass spectrometers When connecting tubing, heed the following recommendations for installing and tightening fittings. Recommendations: •...
  • Page 32 Mark the fitting body at the 9 o’clock position. Ensure that the tubing makes contact with the bottom of the fitting body, and use the 1/4- inch open-end wrench to rotate the compression screw clockwise 3/4-turn until the two marks line up. First use tightening 2.3.1.2 Stainless steel (gold-plated) fitting with long flats and 2-piece stainless steel ferrule (V-detail)
  • Page 33 First use tightening Reinstalled Long flats Compression screw 2-piece stainless steel ferrule Tighten the fitting finger-tight plus as much as an additional 1/6-turn using a 1/4-inch open-end wrench. Reinstalled tightening December 5, 2017, 715004750 Rev. C Page 33...
  • Page 34 2.3.1.3 Stainless steel (gold-plated) fitting with short flats and 2-piece stainless-steel ferrule (V-detail) First use Short flats Compression screw 2-piece stainless steel ferrule Tighten the fitting finger-tight plus an additional 3/4-turn using a 1/4-inch open-end wrench. For detailed instructions about assembling new fittings, see Assembling new fittings.
  • Page 35 Short flats Compression screw 2-piece stainless steel ferrule Tighten the fitting finger-tight plus as much as an additional 1/6-turn using a 1/4-inch open-end wrench. Re-installed tightening 2.3.1.4 One-piece PEEK fitting Figure 2–16: First use or reinstalled Compression screw Tighten the fitting finger-tight. 2.3.1.5 PEEK fitting with PEEK ferrule and stainless steel lock ring First use or re-installed December 5, 2017, 715004750 Rev.
  • Page 36 Compression screw Lock ring Ferrule Tighten the fitting finger-tight. 2.3.1.6 Dual-threaded fitting with locking cap nut Required tools and materials • 1/2-inch open-end wrench Figure 2–17: First use or reinstalled Locking cap nut Gold-plated, locking compression screw Back-locking or standard PEEK ferrule To tighten the fitting: Loosen the cap nut from the compression screw.
  • Page 37 Tip: If you are operating the system at, or close to, its maximum system operating pressure limit, finger-tighten the cap nut onto the compression screw, and then use the 1/2- inch open-end wrench to tighten the compression screw an additional 1/8- to 1/6-turn. Tip: When reinstalling the fitting, •...
  • Page 38 APH assembly location when using columns less than 30-cm long APH key location when using columns less than 30-cm long (APH assembly with retainer is installed in upper control port) Requirements: • Always install the APH key in the control port not occupied by the APH assembly. The APH key must always occupy one of the APH control ports for the CH-30A module to operate.
  • Page 39 2.3.3 Connecting a CH-30A for use with 30-cm columns Waters ships the CH-30A module with the APH key installed in the upper control port so that the APH assembly can be installed in the lower control port, readying the APH for use with 30-cm columns.
  • Page 40 Figure 2–21: CH-30A configuration supporting 30-cm columns Location of upper control port in the column compartment where the APH key is installed Location of lower control port in the column compartment where the APH assembly with retainer is installed For a CH-30A configuration supporting a 30-cm column, the tubing for the column compartment's APH assembly extends from the sample manager's injection-valve outlet.
  • Page 41 Figure 2–22: Flow path for an CH-30A configuration supporting a 30-cm column Column outlet to detector inlet tubing APH key installed in upper control port Column outlet 30-cm column Column inlet APH-to-column assembly APH assembly installed in lower control port APH assembly tubing connected to sample-manager injection valve outlet December 5, 2017, 715004750 Rev.
  • Page 42 Figure 2–23: Connection diagrams for a CH-30A configuration supporting a 30-cm column (and in-line filter) Sample manager Injection Column Detector valve Sample manager Injection Filter Column Detector valve Table 2–1: Legend Identifier Description Length ACQUITY Arc ACQUITY Arc material Bio material APH assembly that connects the 59.7 cm MP35N...
  • Page 43 Table 2–1: Legend (continued) Identifier Description Length ACQUITY Arc ACQUITY Arc material Bio material Dual-threaded fitting with locking SST cap and SST cap and cap nut screw, PEEK screw, PEEK ferrule ferrule Filter Column filter (in-line) 10-32 PEEK fitting with PEEK PEEK and SST PEEK and SST ferrule...
  • Page 44 Figure 2–24: APH assembly (with retainer and APH-to-column tubing assembly) located in lower control port Lower control port APH retainer APH assembly APH-to-column tubing assembly Remove the plug from the column inlet. Loosen the cap nut from the gold fitting on the APH assembly. Slide the APH assembly's gold fitting and captive ferrule into the inlet of the APH-to-column tubing assembly.
  • Page 45 10. Rotate the column (or in-line filter) onto the APH-to-column tubing assembly and finger- tighten the fitting. 11. Tighten the cap nut onto the gold fitting of the APH-to-column tubing assembly. 12. Insert the column-outlet tubing (pre-configured SST assembly, pre-configured MP35N assembly, or PEEK tubing) into the outlet of the column.
  • Page 46 2.3.4 Connecting a CH-30A for use with columns less than 30-cm long Waters ships the CH-30A module with the APH key installed in the upper control port. You must move the APH key to the lower control port so that the APH assembly can be installed in the upper control port, readying the APH for use with small columns (less than 30-cm in length).
  • Page 47 Figure 2–26: CH-30A configuration supporting columns less than 30-cm long Location of upper control port in the column compartment where the APH assembly with retainer is installed Location of lower control port in the column compartment where the APH key is installed For a standard CH-30A configuration, the tubing for the column compartment's APH assembly extends from the sample manager's injection valve outlet.
  • Page 48 Figure 2–27: Flow path for a CH-30A configuration supporting columns less than 30-cm long Column outlet to detector inlet tubing APH assembly installed in upper control port Column inlet Column less than 30-cm long Column outlet APH key installed in lower control port APH assembly tubing connected to sample-manager injection valve outlet December 5, 2017, 715004750 Rev.
  • Page 49 Figure 2–28: Connection diagrams for standard CH-30A configurations supporting columns less than 30-cm (and in-line filter) Sample manager Injection Column Detector valve Sample manager Injection Filter Column Detector valve Table 2–2: Legend Identifier Description Length ACQUITY Arc ACQUITY Arc material Bio material APH assembly connects the 59.7 cm...
  • Page 50 Required tools and materials • 1/4-inch open-end wrench • Chemical-resistant, powder-free gloves • Tubing and fittings supplied with system start-up kit and CH-30A start-up kit Notice: To avoid damaging the preheater assembly, • turn the column onto the preheater assembly when installing or removing the column to prevent the preheater tubing from twisting;...
  • Page 51 Upper control port APH retainer APH assembly Remove the plug from the column inlet. Loosen the cap nut from the gold fitting on the APH assembly. Slide the gold fitting with captive ferrule into the inlet of the column (or in-line filter). Note: For instructions explaining how to install the column in-line filter, see the document ACQUITY UPLC Column In-Line Filter Unit Installation Instructions.
  • Page 52 Figure 2–30: APH and column components assembled Front view Side view eCord fob receptacle APH assembly Column clip Column-outlet tubing While holding the column-outlet tubing, tighten the fitting for the column outlet according to the type of fitting used. For instructions, see Installation recommendations for fittings.
  • Page 53 To control the CH-30A module, enter its compartment temperature settings using the sample manager's control panels or the method editor in Empower software or MassLynx software. For details, refer to the Waters console Help. 2.4.1 Specifying the preheater setting Before operating the system, verify that the column preheater setting is set to Active, to enable active pre-heating.
  • Page 54 The location for leak detection varies according to the column manager configuration. In a single- stack configuration with the CM-A positioned atop the sample manager, the CM-A module's waste drips into the sample manager's upper drip tray. Accordingly, leak detection is afforded by the leak sensor in the sample manager's upper drip tray.
  • Page 55 Figure 2–31: Leak-sensor serrations Serrations Use a nonabrasive, lint-free wipe to dry the leak-sensor prism. Figure 2–32: Leak-sensor prism Leak-sensor prism Roll up a nonabrasive, lint-free wipe, and use it to absorb the liquid from the leak-sensor reservoir and its surrounding area. With a cotton swab, absorb any remaining liquid from the corners of the leak-sensor reservoir.
  • Page 56 Figure 2–33: Column manager leak sensor installed Leak sensor installed in leak-sensor reservoir In the console, select Column Manager from the system tree. 10. In the column manager information window, click Control > Reset CM, to reset the column manager. December 5, 2017, 715004750 Rev.
  • Page 57 Help. 3.1 Contacting Waters Technical Service If you are located in the USA or Canada, report malfunctions or other problems to Waters Technical Service (800-252-4752). From elsewhere, phone the Waters corporate headquarters in Milford, Massachusetts (USA), or contact your local Waters subsidiary.
  • Page 58 Be prepared to provide the serial numbers of the instruments in your system when you consult Waters customer support. Figure 3–1: CH-30A serial number label locations Serial number label on rear panel Serial number label on upper, left-hand side panel inside compartment 3.3 Recommended maintenance schedule...
  • Page 59 Clean the instrument with a soft, lint-free cloth, or paper As necessary dampened with water 3.4 Spare parts To ensure that your system operates as designed, use only Waters Quality Parts. Visit www.waters.com/wqp for information about Waters Quality Parts, including how to order them. 3.5 Safety and handling Observe these warning and caution advisories when you perform maintenance operations on your system.
  • Page 60 Thus you can minimize unexpected failures and unscheduled downtime during important work. For information explaining how to specify maintenance warnings, consult the Waters console Help. 3.7 Replacing the leak sensor Perform this procedure if you must replace a leak sensor in the CH-30A module.
  • Page 61 Notice: To avoid damaging the leak sensor, do not grasp it by the ribbon cable. Tip: When the CH-30A is mounted to the system stack, use a pen to depress the connector tab that releases the leak-sensor connector from the receptacle. Figure 3–2: Location of the receptacle for the leak-sensor cable Receptacle for the leak-sensor connector Remove the leak sensor from its reservoir, grasping it by its serrations, and pulling upward.
  • Page 62 Figure 3–3: Leak sensor Serrations Unpack the new leak sensor. Align the leak-sensor T-bar with the slot in the side of the leak-sensor reservoir, and slide the leak sensor into place. Figure 3–4: Installing the leak sensor Leak-sensor T-bar Leak-sensor cable retainer slot Route the leak-sensor cable through the slot in the leak-sensor cable retainer.
  • Page 63 3.8 Removing a column During scheduled preventive maintenance or when changing methods, you can remove the column in the CH-30A column compartment before replacing it with a new column of the same or different type. If you change to a column of a different length, ensure that the APH key and APH assembly are installed in their proper positions in the compartment, according to size of the replacement column.
  • Page 64 3.9 Replacing the ferrule on the column-inlet fitting Replace the column-inlet ferrule on the APH assembly fitting (or the APH-to-column tubing assembly, if the APH assembly is installed in the CH-30A module's lower-control port) if the column is leaking. Warning: To prevent burn injuries, set the column temperature to Off, and then allow the column compartment and its components to cool for 60 minutes before touching them.
  • Page 65 Figure 3–6: Sliding fitting off tubing Tubing Fitting Result: If the assembly contains a captive ferrule, the ferrule remains locked in the fitting. Remove the captive ferrule from the fitting. Figure 3–7: Removing ferrule from fitting Fitting Ferrule (captive ferrule shown) Discard the used ferrule.
  • Page 66 Figure 3–9: Sliding fitting and ferrule onto tubing Tubing Fitting Result: If it is a captive ferrule, the ferrule locks into the fitting. Screw the cap nut onto the fitting. Figure 3–10: Screwing cap onto fitting Cap nut Fitting 3.10 Replacing the APH assembly This section describes two separate procedures for replacing an APH assembly: one for configurations supporting 30-cm columns, requiring the APH assembly to be installed in the column compartment's lower control port, and the other, for configurations supporting columns...
  • Page 67 Warning: To avoid personal contamination with biologically hazardous or toxic compounds, wear clean, chemical-resistant, powder-free gloves when performing this procedure. Requirement: Wear clean, chemical-resistant, powder-free gloves when performing this procedure. Notice: To avoid damaging the preheater assembly, • turn the column onto the preheater assembly when installing or removing the column to prevent the preheater tubing from twisting;...
  • Page 68 Figure 3–11: Removing assembled APH and column components from the compartment Front view Side view eCord fob receptacle APH assembly Column clip Column-outlet tubing Remove the column clips from the column fittings. While holding the column, disconnect the column-outlet tubing from the outlet of the column.
  • Page 69 10. Set aside the APH assembly for discarding. 11. Unpack the new APH assembly. 12. Using the 1/4-inch open-end wrench, connect the long, flat compression-screw end of the new APH assembly to port 6 of the sample manager's injection valve. Note: For detailed instructions about assembling new fittings, see Assembling new...
  • Page 70 Remove the APH assembly from its control-port retainer and pull the APH assembly, APH- to-column tubing assembly, column (or column and in-line filter), and column-outlet tubing in their entirety from the compartment. Figure 3–12: Removing assembled APH and column components from the compartment eCord fob receptacle Column-outlet tubing...
  • Page 71 APH-to-column tubing assembly (with reusable fitting [shown here] or standard compression fitting [for non-Waters columns]) APH assembly, APH-to-column tubing assembly, column, and PEEK column-outlet tubing installed in compartment APH assembly tubing from port 6 of the sample manager's injection valve Remove the column clips from the column fittings.
  • Page 72 24. Carefully install the APH assembly into its control-port retainer, routing the APH-to-column tubing assembly around the gasket, and aligning the column (or the in-line filter with column) inside the trough (see the figure above). 25. Connect the eCord fob to its receptacle. 26.
  • Page 73 Remove the APH assembly from its control-port retainer, and pull the APH assembly, APH- to-column tubing assembly, column (or column and in-line filter), and column-outlet tubing in their entirety from the compartment. Figure 3–13: Removing assembled APH and column components from the compartment eCord fob receptacle Column-outlet tubing...
  • Page 74 APH-to-column tubing assembly (with reusable fitting (shown here) or standard compression fitting (for non-Waters columns)) APH assembly, APH-to-column tubing assembly, column, and PEEK column-outlet tubing installed in compartment APH assembly tubing from port 6 of the sample manager's injection valve Loosen the cap nut from the gold fitting on the APH-to-column tubing assembly.
  • Page 75 3.12 Cleaning the exterior of the equipment Warning: To avoid electric shock, • ensure that the electrical power to the equipment is interrupted; • when cleaning the surface of the equipment, apply water to a cloth, and then wipe the instrument or device. Do not spray or otherwise apply water directly onto any equipment surface.
  • Page 76 Heed all warnings when you install, repair, or operate any Waters instrument or device. Waters accepts no liability in cases of injury or property damage resulting from the failure of individuals to comply with any safety precaution when installing, repairing, or operating any of its instruments or devices.
  • Page 77 (Risk of high-pressure gas release.) A.1.1 Specific warnings A.1.1.1 Burst warning This warning applies to Waters instruments and devices fitted with nonmetallic tubing. Warning: To avoid injury from bursting, nonmetallic tubing, heed these precautions when working in the vicinity of such tubing when it is pressurized: •...
  • Page 78 A.1.1.2 Biohazard warning The following warning applies to Waters instruments and devices that can process material containing biohazards, which are substances that contain biological agents capable of producing harmful effects in humans. Warning: To avoid infection with potentially infectious, human-sourced products, inactivated microorganisms, and other biological materials, assume that all biological fluids that you handle are infectious.
  • Page 79 Use eye protection when performing this procedure. Requirement: Wear clean, chemical-resistant, powder-free gloves when performing this procedure. A.5 Warnings that apply to all Waters instruments and devices When operating this device, follow standard quality-control procedures and the equipment guidelines in this section.
  • Page 80 警告： 未經有關法規認證部門允許對本設備進行的改變或修改,可能會使使用者喪失操作 該設備的權利。 警告： 未经有关法规认证部门明确允许对本设备进行的改变或改装，可能会使使用者丧 失操作该设备的合法性。 경고: 규정 준수를 책임지는 당사자의 명백한 승인 없이 이 장치를 개조 또는 변경할 경우, 이 장치를 운용할 수 있는 사용자 권한의 효력을 상실할 수 있습니다. 警告: 規制機関から明確な承認を受けずに本装置の変更や改造を行うと、本装置のユーザーとして の承認が無効になる可能性があります。 Warning: Use caution when working with any polymer tubing under pressure: •...
  • Page 81 Warnung: Bei der Arbeit mit Polymerschläuchen unter Druck ist besondere Vorsicht angebracht: • In der Nähe von unter Druck stehenden Polymerschläuchen stets Schutzbrille tragen. • Alle offenen Flammen in der Nähe löschen. • Keine Schläuche verwenden, die stark geknickt oder überbeansprucht sind. •...
  • Page 82 圧力のかかったポリマーチューブを扱うときは、注意してください。 • 加圧されたポリマーチューブの付近では、必ず保護メガネを着用してください。 • 近くにある火を消してください。 • 著しく変形した、または折れ曲がったチューブは使用しないでください。 • 非金属チューブには、テトラヒドロフラン(THF)や高濃度の硝酸または硫酸などを流さないでくださ い。 • 塩化メチレンやジメチルスルホキシドは、非金属チューブの膨張を引き起こす場合があり、その場 合、チューブは極めて低い圧力で破裂します。 This warning applies to Waters instruments fitted with nonmetallic tubing. This warning applies to instruments operated with flammable solvents. December 5, 2017, 715004750 Rev. C Page 82...
  • Page 83 Warning: The user shall be made aware that if the equipment is used in a manner not specified by the manufacturer, the protection provided by the equipment may be impaired. Avertissement : L’utilisateur doit être informé que si le matériel est utilisé d’une façon non spécifiée par le fabricant, la protection assurée par le matériel risque d’être défectueuses.
  • Page 84 Avertissement : pour éviter tout risque d'incendie, remplacez toujours les fusibles par d'autres du type et de la puissance indiqués sur le panneau à proximité du couvercle de la boite à fusible de l'instrument. Warnung: Zum Schutz gegen Feuer die Sicherungen nur mit Sicherungen ersetzen, deren Typ und Nennwert auf den Tafeln neben den Sicherungsabdeckungen des Geräts gedruckt sind.
  • Page 85 警告： 為了避免火災，更換保險絲時，應使用「維護步驟」章節中「更換保險絲」所指 定之相同類型與規格的保險絲。 警告： 为了避免火灾，应更换“维护步骤”一章的“更换保险丝”一节中介绍的相同类 型和规格的保险丝。 경고: 화재의 위험을 막으려면 유지관리 절차 단원의 “퓨즈 교체” 절에 설명된 것과 동 일한 타입 및 정격의 제품으로 퓨즈를 교체하십시오. 警告: 火災予防のために、ヒューズ交換ではメンテナンス項目の「ヒューズの交換」に記載されているタ イプおよび定格のヒューズをご使用ください。 A.7 Electrical symbols The following electrical symbols and their associated statements can appear in instrument manuals and on an instrument’s front or rear panels.
  • Page 86 A.8 Handling symbols The following handling symbols and their associated statements can appear on labels affixed to the packaging in which instruments, devices, and component parts are shipped. Symbol Description Keep upright! Keep dry! Fragile! Use no hooks! Upper limit of temperature Lower limit of temperature Temperature limitation December 5, 2017, 715004750 Rev.
  • Page 87 Specifications B.1 CH-30A physical specifications Attribute Specification Height 51.3 cm (20.2 inches) Width 13.4 cm (5.3 inches) Depth (without drip tray fitting) 14.8 cm (5.8 inches) Weight 5.0 kg (11.0 pounds) Access to APH assembly, APH-to- Inside column compartment via access door column tubing assembly, column in- line filter, column, and column-outlet tubing...
  • Page 88 B.3 CH-30A electrical specifications Attribute Specification Pollution degree Normal (IPXO) Moisture protection Line voltages, nominal Power requirements 24 V Line frequency 0 Hz Power consumption 50 W a. Pollution Degree 2 – A measure of pollution on electrical circuits that can produce a reduction of dielectric strength or surface resistivity.
  • Page 89 Item Specification Leak control Compartment drip tray with leak sensor installed under compartment; single exit drain manages leaks to waste Door open to heater cutoff 1-minute maximum delay Column tracking eCord technology column information management tracks and archives column usage history a.