Biotage PRESSURE+ 96 User Manual
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Biotage PRESSURE+ 96 User Manual

Positive pressure manifold
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Biotage PRESSURE
BIOTAGE SWEDEN AB
Box 8, SE-751 03 Uppsala, Sweden
Visiting Address: Vimpelgatan 5
Switchboard: +46 (0)18 56 59 00
info@biotage.com, www.biotage.com
Positive Pressure Manifold
User Manual
US TECHNICAL SUPPORT
Phone: +1 800 446 4752 press 3
US-1-pointsupport@biotage.com
413248-A
+
96
EU AND GLOBAL TECHNICAL SUPPORT
Phone: +46 (0)18 56 59 11
EU-1-pointsupport@biotage.com

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Summary of Contents for Biotage PRESSURE+ 96

  • Page 1 413248-A Biotage PRESSURE Positive Pressure Manifold User Manual BIOTAGE SWEDEN AB US TECHNICAL SUPPORT EU AND GLOBAL TECHNICAL SUPPORT Box 8, SE-751 03 Uppsala, Sweden Phone: +1 800 446 4752 press 3 Phone: +46 (0)18 56 59 11 Visiting Address: Vimpelgatan 5 US-1-pointsupport@biotage.com...

  • Page 2: Table Of Contents

    Replace the Column Seal............... 13 Clean ....................13 General Information ................14 Trademarks..................14 Copyright .................... 14 Manufacturer ..................14 Contact Us ..................14 Sales Offices and Distributors ............. 14 Technical Support ................15 PRESSURE+ 96 User Manual Page 2 of 15...

  • Page 3: Safety

    Safety Intended Use Biotage PRESSURE+ 96 is intended for laboratory use only and has to be operated by trained professionals. All operations must be performed:  According to the user documentation delivered with the equipment.  According to instructions available at www.biotage.com.

  • Page 4: Safety Considerations

    Safety Considerations Many reagents and samples used with PRESSURE+ 96 can pose chemical, biological and radiological hazards. You must always understand the potentially hazardous effects of all the materials you work with. To prevent personal injury and/or equipment damage, we recommend that you always use impermeable gloves, chemical safety goggles and protective clothing, follow GLP (Good Laboratory Practice), and consult your company’s safety expert for guidance.

  • Page 5: Installation

    Installation Site Requirements The PRESSURE+ 96 unit should be placed in a laboratory and operated where there is proper ventilation or from inside a chemical fume hood when volatile solvents are used. The PRESSURE+ 96 unit requires a compressed gas supply, and should be located with this in mind.
  • Page 6 Slight movement may occur as the unit pressurizes. NOTE: Biotage recommend that the boxes and packing materials are retained by the customer in case the unit needs to be transported or stored. PRESSURE+ 96 User Manual...

  • Page 7: Packing List

    Note that the unit weighs 11.8 kg. Connect the gas line to the right port at the back of the unit. Packing List PRESSURE+ 96 is shipped with the following items: Quantity Description Part Number...

  • Page 8: System Description

    Note that collection plates should allow for venting of the positive pressure. Standard 1 mL and 2 mL collection plates from Biotage will allow venting when paired with any of the 96-well formats from Biotage.

  • Page 9: Flow Control

    Flow Control The PRESSURE+ 96 unit has a two-tier gas delivery system. The flow control switch (B) enables setting and operation of gas flow in addition to turning gas flow on and off:  Adjustable Flow Rate (0 to 15 psi, 0 to 2.5 scfh) Recommended for sample loading and elution.

  • Page 10: Operation

    1. Ensure the unit is connected to a gas supply; see Installation section on page 5. 2. Place a 96-well collection plate on the platform. 3. Place a 96-well extraction plate on top of the collection plate. 4. Load each well with conditioning solvent. PRESSURE+ 96 User Manual Page 10 of 15...
  • Page 11 6. Turn the flow control switch to the left to the Adjustable Flow position. 7. Adjust the regulator and rotometer to achieve the desired flow rate. 8. Lower the manifold by pressing down on the two rocker switches simultaneously for approximately 3 seconds. PRESSURE+ 96 User Manual Page 11 of 15...
  • Page 12 Tip: To trigger gravity elution, slide the platform back to position the plate under the manifold, ensure the flow control switch is in the OFF position and then lower the manifold. Raise the manifold after a few seconds. PRESSURE+ 96 User Manual Page 12 of 15...

  • Page 13: Maintenance

    You need a 96-column seal, a hex key and four positioning screws (part number PPM-A96-GSKT), and a Philips screwdriver (PH2). In order to maintain compliance, column seals supplied by Biotage must be used with the unit. 1. Shut off the external gas supply.

  • Page 14: General Information

    Information in this document is subject to change without notice and does not represent any commitment from Biotage Sweden AB. All contents © 2011 Biotage Sweden AB. All rights reserved. No material may be reproduced or published without the written permission of Biotage Sweden AB.

  • Page 15: Technical Support

    (www.biotage.com). When contacting 1-Point Support, please have the following information ready:  Company name and contact information.  Serial number of your PRESSURE+ 96 (see the product label at the rear of the unit).  A brief description of the symptoms or technical problems you are experiencing.

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