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TurboVap
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User Manual

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Summary of Contents for Biotage TurboVap

  • Page 1 TurboVap ® User Manual...
  • Page 2: Table Of Contents

    Clean the Racks and Manifolds Clean the Water Bath Replace a Multi Rack Height Adjustment Handle Replace a Multi Rack Vial Spring Replace a Nozzle Replace an End-Point Sensor Replace the Fuse Long Term Storage TurboVap User Manual | © Biotage 2017 ®...
  • Page 3: System Overview

    0.2 mL, and tubes with a 1.0 mL stem concentrate Figure 2. TurboVap LV manifold with 48 nozzles. In the picture to the right, to 0.7 mL. They all have a ±5% calibrated mark on the tube for 24 nozzles are plugged for usage with the multi rack with 24 positions.
  • Page 4: Racks And Tube Sizes

    Figure 4 . TurboVap LV multi racks with 48 positions (left) and 24 positions (right). Figure 7 . Gas vortex shearing action. Figure 5 . TurboVap II rack with (left) and without (right) end-point sensors. Ventilation Solvent vapors are removed by an exhaust fan and routed to the exhaust port at the rear of the system.
  • Page 5: Sleep Mode And Automatic Wake-Up

    System Overview Sleep Mode and Automatic Wake-Up The system can be put in sleep mode either manually or by scheduling a sleep time. It will also enter sleep mode if the lid is left open for more than 90 minutes. When entering sleep mode, the system turns off the heater and the water bath light (if on), and activates the screen saver.
  • Page 6: Determine Optimal Evaporation Conditions

    24 nozzles are plugged on the manifold (see Figure 2 on status field when the sample has been evaporated to dryness or page 1 on how to plug the TurboVap LV manifold), the to the desired liquid level. 24-position or Extrahera 1 x 24 manifold option must be selected in the software's settings view (see page 6).
  • Page 7: Determine The Appropriate Evaporation Mode

    » The desired end-point volume is greater than 0.2 or 0.7 mL. » The two end-point detection modes are only enabled when a TurboVap II end-point rack has been connected to the system's AUX port. System Ready Evaporate Settings 12:44 Wed 23 Nov 2016...
  • Page 8: Define System Settings

    The system can be put in sleep mode either manually by Save pressing the orange button in the settings view (see Figure 10) or automatically by scheduling a sleep time in the sleep mode Figure 11 . The Sleep Mode view. TurboVap User Manual | © Biotage 2017 ®...
  • Page 9: Calibrate The Water Bath Temperature

    Define System Settings Calibrate the Water Bath Temperature The water bath temperature can be adjusted after calibrating at two temperatures that encompass (above and below) the range of temperatures used in your applications. 1. Set the evaporation mode to Manual or Time. 2.
  • Page 10: Prepare The System

    DRAIN port. B: Add deionized water until the water’s surface is as high as recommend the following procedure. the initial liquid level will be in the tubes but not higher than just below the blue water bath top cover. TurboVap User Manual | © Biotage 2017 ®...
  • Page 11: Adjust The Nozzles

    1. Ensure that the water level is correct; see instructions above. 3. When the target water bath temperature has been reached, 2. If using the TurboVap LV multi rack with 24 positions or the the user will be notified by a dialog on the touch screen (see TurboVap EH sample/collection rack holder with only one Figure 18) and an audible alarm.
  • Page 12: Evaporate

    24 nozzles are plugged on the manifold (see Figure 2 sufficient reserve for the run. on page 1 on how to plug the TurboVap LV manifold), 3. If using a rack with end-point sensors, gently lower the rack...
  • Page 13: Monitor An Evaporation Run

    Evaporate Monitor an Evaporation Run An audible alarm will also sound (but only once) each time the end-point level (+ any additional time) is reached for a single tube. During the evaporation run, the current and set values for the water bath temperature, gas flow, and time can be monitored on Note: The alarm and water bath light can be turned off in the the touch screen;...
  • Page 14: Define Methods

    Method 5 Method 10 End-Point: 10 min Edit Rename Figure 23 . The Method view where you select the method you want to run, or modify a method and then run it. TurboVap User Manual | © Biotage 2017 ®...
  • Page 15: Maintenance

    » The power cord should be inspected periodically and replaced if by pressing on the top of the DRAIN port (see Figure 25B). damaged or altered. Use only a power cord supplied by Biotage. d. Empty the waste container. »...
  • Page 16: Replace A Multi Rack Height Adjustment Handle

    Replace the Fuse Warning Figure 28. Releasing a vial spring. » Use only exact replacement fuses supplied by Biotage. Incorrect fuses create a potential fire hazard and personal injury. Replace a Nozzle 1. Turn off the system and disconnect the power cord.
  • Page 17: Long Term Storage

    4. Replace the old fuse. 5. Put the fuse holder back in place by pushing it in and turning it clockwise until it locks. If the fuse blows shortly after replacing it, please contact Biotage 1-Point Support ® ™ Figure 31. Removing the fuse holder.
  • Page 18: Troubleshooting

    If there is no or slow evaporation in a single tube: » » When using a system with TurboVap II configuration, If the end-point modes are disabled in the ensure that the nozzles for all rack positions that software, ensure that an end-point rack has contain sample tubes are enabled in the software.
  • Page 19: General Information

    General Information General Information Accessories and Spare Parts Part No. Description Only genuine Biotage accessories must be used in the system. C47811 10 mL Conical Centrifuge Test Tube To order consumables and accessories, see contact information on C44941 15 mL Conical Centrifuge Test Tube the back of this document or visit our website www.biotage.com.
  • Page 20 Part Number: 415390-C © 2017 Biotage. All rights reserved. No material may be reproduced or published without the written permission of Biotage. Information in this document is subject to change without notice and does not represent any commitment from Biotage. E&OE.

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