Application Part: Tube Kit; The Efficiency Of Vaporized Dronabinol (Thc); Application; Inhalation - Vapormed Volcano MEDIC 2 Instructions For Use Manual

6 . T H E U S E O F D R O N A B I N O L

6.3. Application Part: Tube Kit

6.3.1. Efficiency of vaporized Dronabinol (THC)
By following the procedure listed in the Instructions for Use the systemic bioavail-
ability of vaporized dronabinol is approximately 33%.
For comparison: The systemic bioavailability of cannabinoids administered orally
is below 15%.
When observing the Instructions for Use and with a vaporization temperature of
210°C (410°F) the following reference values are validated in studies:
Drug
(Filling
Chamber Con-
tent)
Dronabinol/THC
(10 mg)
If dosage is too low increase the amount of dronabinol.
If dosage is too high reduce the amount of dronabinol.

6.3.2. Application

Before using the Tube, switch
off the pump by pressing the
touch button pump (AIR).
When the actual temperature has
reached 210°C (410°F), place the Tube
Kit on the Filling Chamber and let it
lock in place.
Cannabinoid
content in drug
THC: 10 mg
99
Cannabinoid
content in Valve
Balloon after
vaporization with
210°C (410°F)
approx. 5 mg

6.3.3. Inhalation

Tube with attached Mouthpiece
Slowly inhale the vapor from the Tube
with the Mouthpiece attached for a
few seconds.
Cannabinoid
content in blood
stream (systemic
bioavailability)
after inhalation
approx. 3,3 mg