Thermo Scientific Multidrop Pico 1 Operating Manual

Thermo Scientific Multidrop Pico 1 Operating Manual

Digital dispenser

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Thermo Scientific™
Multidrop™ Pico 1 Digital Dispenser
Operating manual
Cat. no. 1509060 Rev. 01

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Summary of Contents for Thermo Scientific Multidrop Pico 1

  • Page 1 Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Cat. no. 1509060 Rev. 01...
  • Page 2 Copyright  2020 Thermo Fisher Scientific Inc. All rights reserved. Microsoft and Windows are registered trademarks of the Microsoft group of companies. All other trademarks and registered trademarks are the property of their respective holders. Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in product operation.
  • Page 3: About This User Manual

    Note Marks a tip, important information that is useful in the optimum operation of the system, or an item of interest. Tip Gives a helpful hint for getting the most out of the software functionality. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 5: Table Of Contents

    Loading a plate ................21 Cassette prompt and loading a cassette .......... 21 Loading a cassette ................. 22 Load fluid prompt ................ 22 Modifying load volume ..............23 Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 6 Load and validate ................. 31 Fluid and Dispense............... 32 Adjust ..................32 A1 realignment ................33 Preventive maintenance completion form ........34 Legal and regulatory notices ..............35 Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 7: Introduction To The Multidrop Pico Dispenser

    It increases research productivity by reliable results provided at higher speed using flexible and intuitive experiment design software. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 8: Advantages Of The Multidrop Pico Dispenser

    Avoid carry-over and contamination with single use, non-contact dispensing supplies. The Multidrop Pico dispenser is applicable to many low- volume assay procedures with one system. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 9: Chapter 2 Safety

    If the fluids are known or suspected to be an inhalation or contact hazard, use the Multidrop Pico dispenser in an enclosure, with an exhaust, such as a lab fume hood. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 10: Electrical Safety

    DHCs do not require any special disposal procedures except for those pipette tips required for the chemicals, which have been placed in them, by your laboratory. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 11: Ergonomic Safety

    Pico dispenser computer. Additional Contact the Service Help Desk for additional assistance. The contact information can be found in the Multidrop Pico dispenser Service and assistance Support document. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 12: Chapter 3 System Specifications

    Temperature: 20°C - 30°C laboratory conditions (68 - 86°F) operating • Humidity: 30% - 80% RH conditions Shipping and • Temperature: 10°C - 32°C (50°F – 90°F) storage • Humidity: 20% - 80% RH conditions Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 13: Compatible Well Plates

    Meet ANSI specifications for footprint dimensions and well locations, if applicable. • Between 4mm and 47mm in height. Additional See the Multidrop Pico dispenser Software User Guide for more system specifications. specifications Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 14: Understanding The Multidrop Pico Dispenser

    Plate height adjustment lock Motorized stage and destination plate holder Destination plate Plate clamp Power switch and indicator light Power and USB connections PC with Multidrop Pico dispenser software Cassette holder Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 15: Assembly And Startup

    The Multidrop Pico dispenser requires a level bench space which is at least 40 cm (16 inches) wide, 32 cm (13 inches) deep, and 23 cm (9 inches) high. This does not include space for the required computer. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 16 Use the USB cable that came with the Multidrop Pico dispenser to connect the computer to the Multidrop Pico dispenser. The USB port is on the back of the Multidrop Pico dispenser (see below, right). Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 17: Adjusting The Cassette-To-Plate Height

    The space should be ~1.25 mm. Gently tighten the knob and remove the cassette. The height adjustment can also be made at protocol runtime before the actual dispensing or during A1 alignment check before actual dispensing. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 18: Chapter 5 Running A Protocol

    Fluid dispensing begins when the plate and cassette are loaded and fluid reservoir has been filled for dispensing. The sections of the Run Window for this phase are: Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 19: Status Area

    This may be used if an incorrect fluid has been loaded into the cassette. Warning status messages may be displayed for both Show Plate and Cancel Fluids. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 20: Well Plate Grid Display

    Note If Require and validate plate ID option has been selected in Run Settings, you must enter a Plate ID and re-enter that ID each time the plate is re-loaded so it can be validated. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 21: Loading A Plate

    Cassette prompt When a cassette is required, a Cassette Load prompt is displayed, indicating the type of cassette required. and loading a cassette Load a cassette Load a cassette Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 22: Loading A Cassette

    The prompt has an entry for fluids used in the protocol, color-coded prompt and number-coded (in concert with the numbered cassette reservoirs) with stock concentration and the required load volume. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 23: Modifying Load Volume

    To modify load volume, move the cursor over the volume on the monitors and click when highlighted. A popup box allows the dispensehead volume to be modified. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 24: Loading The Fluids

    Do NOT depress the pipette plunger to the second “blow out” stop because this could introduce air into the dispensehead. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 25 Insert the pipette tip directly into the opening. Do NOT depress the plunger to the second “blow out’ stop Examples of good and bad load on high-volume cassettes: Good load Bad load Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 26: Fluid Dispensing

    Cassette As additional cassettes are needed, dispensing will pause and, you will be prompted to load a new cassette and the fluid needed for that changes cassette. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 27: Preventative Maintenance Procedures

    Clean the Multidrop Pico dispenser according to the cleaning procedures described in the Cleaning the Multidrop Pico dispenser section below. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 28: Cleaning The Multidrop Pico Dispenser

    • The destination plate holder. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 29: Pogo Pin Inspection

    Pogo pins that are bent or not fully extended must be replaced (contact Support). Tip the dispenser back upright and plug the cables back in. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 30: Pogo Pin Cleaning

    Multidrop Pico dispenser Service and Support document. Click A1 Alignment on the Advanced tab of the ribbon. The A1 Alignment dialog opens as shown below. Select the well plate type that you are aligning. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 31: Load And Validate

    Place a clear lid or plate seal on the plate. validate After the cassette and plate are loaded, click Next and they will be validated. If necessary, you will be prompted again for cassette and/or plate load. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 32: Fluid And Dispense

    After dispensing, the plate will be moved to a position where it can be Adjust examined or removed for closer examination. If the alignment is correct, you can simply exit the procedure by clicking the Close button. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 33: A1 Realignment

    Remember to clean the plate cover or seal before re-dispensing. The usual procedure is to adjust and re-dispense to verify the adjustment until alignment is good. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 34: Preventive Maintenance Completion Form

    Pogo Pin Cleaning ν A1 Alignment Check ν ν A1 Realignment The undersigned confirms that these Preventive Maintenance procedures have been performed: PM(s) Performed By Email Signature Date Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 35: Legal And Regulatory Notices

    0.1 weight % and 0.01 weight % for cadmium, except where allowed pursuant to the exemptions set in Schedule 2 of the Rule. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 36 Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 37 Hävitettävien laitteiden erillinen keräys ja kierrätys säästää luonnonvaroja. Näin toimimalla varmistetaan myös, että kierrätys tapahtuu tavalla, joka suojelee ihmisten terveyttä ja ympäristöä. Saat tarvittaessa lisätietoja jätteiden kierrätyspaikoista paikallisilta viranomaisilta, jäteyhtiöiltä tai tuotteen jälleenmyyjältä. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 38 Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 39 Kommunala myndigheter, sophanteringsföretag eller butiken där varan köptes kan ge mer information om var du lämnar kasserade produkter för återvinning. 欧盟国家/地区⽤户在私⼈住宅中对废旧设备的处理 产品或包装上包括此标志表⽰此产品不得作为住宅垃圾来处理。⽽且您有 责任将废旧设备送到指定的废旧电⼒电⼦ 设备回收点,通过这种⽅式来 处理废旧设备。废旧设备的分类收集与回收有助于节约⾃然资源,保证以 有利于⼈类 健康和环保的⽅式回收废旧设备。有关废旧设备回收的详细 信息,请与当地市政机关、家庭垃圾处理站或购买产品 的商店联系。 Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 40 消耗品 外壳面板 激光检测仪 媒体(CD ) 电机组件 印刷电路组 件 / 电气元件 电源适配器/ 电源 传感器 静电消除棒 本表格依据SJ/T 11364 的规定编制。 O:表示该有害物质在该部件所有均质材料中的含量均在GB/T 26572 规定的限量要求以下。 X:表示该有害物质至少在该部件的某一均质材料中的含量超出GB/T 26572 规定的限量要求。 此表中所有名称中含 表中所有的部件均符合欧盟 RoHS 立法。 注:环保使用期限的参考标识取决于产品正常工作的温度和湿度等条件 Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 41 (Cr(VI)) (PBB) (PBDE) Cable / Wiring Chassis Consumable Outer Cover Panel Laser Detector Media (CD) Motor Assembly PCA / Electrical Component Power Adapter / Supply Sensor Static Elimination Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...
  • Page 42 European Union’s RoHS Legislation. Note: The referenced Environmental Protection Use Period Marking was determined according to normal operating use conditions of the product such as temperature and humidity. Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual Thermo Fisher Scientific...
  • Page 43 Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 1 Digital Dispenser Operating manual...

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