Maintenance Procedures; After Each Use; Monthly Maintenance; Semiannual Maintenance - CEM Discover Bio Installation And Operation Instructions Manual

Maintenance Procedures

After Each Use

•
Clean the thermowell by wiping with a dry, lint-free cloth.
•
If cleavagae was performed, clean the Product lines.
•
Connect a 50 mL centrifuge tube to the product position.
•
Open the reaction vessel and add ~20 mL dichloromethane to the reaction vessel. Close the
reaction vessel.
•
With the pump turned on, turn the right knob to "Product" to drain the dichloromethane into
the centrifuge tube.
•
Repeat with an additional 20 mL dichloromethane.

Monthly Maintenance

•
Replace the dip tube filters in the main solvent and deprotection bottles.

Semiannual Maintenance

•
Replace the Wash Solvent with methanol and perform a wash of the reaction vessel.
•
Replace the frit on the bottom of the reaction vessel.
Replacement of Reaction Vessel Frit
1. Remove the drain line from the bottom of the reaction vessel.
2. Open the reaction vessel by pressing up into the reaction vessel top and rotating.
16
Discover Bio Manual Microwave Peptide Synthesizer
™
600423 • Revision 2 • August 2017