Leaks In Capillary Flow (Microfluidic) Fittings - Agilent Technologies 6890N Troubleshooting Manual

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Checking for Leaks

Leaks in Capillary Flow (Microfluidic) Fittings

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For capillary flow fittings, a leak usually indicates that the
fitting has been overtightened. Unless the fitting is obviously
loose, do not tighten it further. Instead, remove the connection,
trim the column end, and install it again. (See To Attach a
Capillary Column Using SilTite Metal Fittings.)
Also inspect the plat and connection for a broken column tip.
Troubleshooting