Introduction; System Components - Merck Milipore Cellicon Perfusion Solution for Process Development User Manual

Cellicon Perfusion Solution for Process Development User Guide
TM

Introduction

The Cellicon Perfusion Solution for Process
TM
Development includes scalable, single-
use filters and controllers that enable seed
train process intensification in upstream
biomanufacturing. The filtration technology
provides high throughput and membrane
efficiency in a closed assembly, while
maintaining a low shear environment to
support cell growth.
This guide describes the installation, setup
and use of the Cellicon Perfusion Solution
TM
for Process Development.
This system is for industrial use only and
cannot be used in a residential environment.

System Components

The Cellicon Perfusion Solution for Process Development includes a single-use filter and
TM
assembly, a holder for the assembly, a controller, a low-shear centrifugal pump, flowmeter and
feed pressure sensor.
Cellicon Cell Retention Device
®
and Single-use Assembly
Perfusate (Permeate)
Pressure Sensor
Assembly Holder
Controller
Cellicon Perfusion Solution for Process Development
TM
Retentate Pressure
Sensor
Feed Pressure Sensor
Flowmeter
Pump
2