The Importance Of Thoughtful Study Design - Izon qNano User Manual

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THE IMPORTANCE OF THOUGHTFUL STUDY DESIGN

Any high-quality TRPS study includes the following aims and considerations:
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Decide what questions you want to answer, what TRPS outputs you
need to measure, and which ones you need to control.
Include sufficient controls and replicates to ensure accurate, precise, and
statistically significant results. Ensure that you have sufficient sample
volume available.
Ensure that the target particles and suspension conditions are
fundamentally compatible with TRPS. Sample particles must be
between 45 – 10,000 nm in size, suspended in a buffer, and of sufficient
concentration for analysis.
Ensure that you understand the properties of your sample and
ensure that the structure and function of your particles will not
be compromised at any point, by using properly validated sample
preparation and storage protocols.
Determine how you will optimise the instrument operating conditions to
maximise data quality (optimise the signal-to-noise ratio).
Ensure that you have the correct consumables.
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