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Summary of Contents for Izon EXOID
- Page 1 E X O I D U S E R M A N U A L www.izon.com...
- Page 2 Izon Science Limited provides this document to its customers with a product purchase to use in the product operation. This document is copyright protected and any reproduction of the whole or any part of this document is strictly prohibited, except with the written authorisation of Izon Science Limited.
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Page 3: Table Of Contents
Hazards ..................................6 Intended Use ................................7 Assembly and Setup Instructions ........................ 8 System Components ............................... 8 Assembling and Installing the Exoid ........................9 Instrument Power and General Operation ...................... 9 General Operating Procedures ..........................9 Computer Setup ..............................10 Operations Instructions ..........................12 Required Materials .............................. -
Page 4: Definitions And Writing Conventions
Table 1: Safety and Hazard Symbols This symbol indicates general advice on how to improve procedures or recommends measures to take in specific situations. This symbol indicates where special care should be taken. Direct Current (DC) Voltage polarity of the jack www.izon.com... - Page 5 Shielding lid Hinged cap on the top face of the Exoid which opens to reveal the fluid cell and nanopore working area. Closing this will reduce noise from external sources such as large machinery and fluorescent lighting.
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Page 6: Safety And Hazards
Good Laboratory Practices (cGLPs) and comply with any local guidelines specific to your laboratory and location. Fire or Electrical Hazard The Exoid poses no uncommon electrical or fire hazard to operators if installed and operated properly without physical modification and connected to a power source of correct specification. www.izon.com... -
Page 7: Intended Use
Izon Science office. Disposal The Exoid system contains electrical materials; it should be disposed of as unsorted waste and must be collected separately, according to the European Union Directive: Waste Electrical and Electronic Equipment. -
Page 8: Assembly And Setup Instructions
The following components are provided in the box: Exoid Instrument Lower Fluid Cell Shielding Cap 24 V Power Supply Upper Fluid Cell Power Lead 10 MΩ Reference Cell USB-A to USB-C Cable Figure 1: The Exoid and components with an Exoid. www.izon.com... -
Page 9: Assembling And Installing The Exoid
Connect the power lead to the 24 V power supply. Ensure the Exoid is switched off, and if the power socket at the wall has a switch, ensure the switch is turned off. Plug the power lead into a wall socket and connect the cable from the 24 V power supply to the rear of the instrument. -
Page 10: General Operating Procedures
Always use USB cables supplied by Izon to connect the Exoid to the computer. Minimum Computer Specifications For the Exoid and ECS to work effectively, the minimum PC requirements must be in place. These are as follows: 16 GB RAM... - Page 11 Windows Home is not suitable for the installation of the ECS. Ensure that the computer is installed with Windows Pro. An onboard graphics card is not suitable for the operation of the Exoid. Ensure that the connected computer has a dedicated GPU with at least 1 GB of memory and that the computer will use this GPU while the ECS is running.
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Page 12: Operations Instructions
OPERATING INSTRUCTIONS The Exoid is a Tunable Resistive Pulse Sensing (TRPS) instrument, and requires an understanding of the principles of TRPS to be able to effectively operate the instrument and interpret the data outputs. Information on the principles of TRPS can be found in the Fundamentals of Tunable Resistive Pulse Sensing Theory Manual at support.izon.com... -
Page 13: Exoid Lighting
4.2 Exoid Lighting The ring of LED lights located below the buttons provides visual indications on the state of the Exoid, as described in Table Table 4: Description of Exoid state as indicated by the halo lighting H A L O CO L O U R... -
Page 14: Fluid Cell
Lower fluid cell paste. Figure 2: A cross section of the Exoid fluid cell, showing the upper and lower fluid cells, the nanopore, the lower electrode paste, and the electrolyte holding areas for normal operation. The pressure application device (PAD) is used to tap or plunge when stabilising the system;... -
Page 15: Exoid Control Suite Software
4.4 Exoid Control Suite Software If using a laptop to operate the Exoid, ensure that the laptop charging cable is plugged in and providing power at all times during operation of the instrument. Once the instrument is connected to the computer and switched on, open the Exoid Control Suite (ECS). - Page 16 To enter this section, nanopore setup is recommended but it is not required. Controlling the Exoid The Exoid has three components that require interaction to achieve a successful sample measurement; the APS which controls pressure, the VCA which controls voltage, and the Delta which controls stretch.
- Page 17 Additionally, the Delta can be controlled via the stretch control buttons near the top of the Exoid above the halo. The Exoid has built-in limit switches to prevent the stretcher being moved to a position that will damage the winding mechanism, these are located at ~41 and ~51 mm. The user will not be able to stretch beyond these values.
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Page 18: Troubleshooting
Remove the fluid cell from the Exoid and replace the lower fluid cell with the reference cell. At 0 mV the current should be 0 ± 3 nA, at 1000 mV the current should be 100 ± 3 nA, and at -1000 mV the current should be -100 ±... - Page 19 Power Cycling Follow these instructions carefully when the need to power cycle the instrument arises. Turn off the switch on the Exoid. The off position is where the full ”O” symbol is pressed down as indicated in Figure Unplug the USB and power cables from the Exoid.
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Page 20: Further Support
DO NOT soak any part of the fluid cell. Repair and Servicing There are no user-serviceable parts. Return equipment to Izon for service. Figure 9: Compliance label attached to the Exoid with CE and UKCA marking. www.izon.com... - Page 21 When reporting Exoid issues to Izon support, please provide the serial number of the Exoid (Figure 10). Figure 10: The serial number can be found either on the back of the Exoid or, as pictured: inside the back leg of the Exoid. Rev G Exoid User Manual...
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