Tuning - Agilent Technologies 6490 Manual Book

6400 series triple quadrupole lc/ms system
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Agilent MassHunter Workstation Software - Data Acquisition for 6400 Series Triple Quadrupole

Tuning

Figure 35
Autotune in progress
Agilent 6400 Series Triple Quad LC/MS Concepts Guide
Autotune and Checktune
A Checktune can be used to determine if the tuning mix ion
masses are properly assigned and if the response or sensitivity
of these ions is within expectations. This check tune takes up to
15 minutes to run. An Autotune can be used if a more extensive
tune is recommended
6490, an Autotune can take 15 to 20 minutes for each polarity;
the 6490 takes approximately 45 minutes per ionization mode.
Everything is automatic since the tuning mix is delivered by the
calibrant delivery system (CDS), which is switched on
automatically during the tune.
(Figure
35). For all models except the
4
Tuning
67

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