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Agilent Triple Quadrupole MS and Sensitivity
3
Collision cell
Pre-filter
The end section of the MS1 (Q1) quadrupole assembly also
consists of short hyperbolic rods, but their RF voltages are only
high enough to guide ions into the collision cell. A similar set of
rods on the exit side of the collision cell are part of the MS2
(Q3) quadrupole. These short RF-only rods act as pre- and
post-filters to the collision cell to ensure optimum ion
transmission.
Collision cell
What is the curved collision cell?
The collision cell is a major innovation. The hexapole field axial
focusing curved collision cell includes a tapered cell structure
for increased ion acceptance at the entrance. Its structure
reduces the ionizer generated noise.
What is the collision cell?
The collision cell is another innovation. The collision cell is
a high pressure hexapole assembly with its linear acceleration
adjusted to optimize MS/MS fragmentation while eliminating
crosstalk even at very low dwell times
(Figure
26).
Agilent 6400 Series Triple Quad LC/MS Concepts Guide
57
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