Page 1 AquaWIT V AW05 Operating Instructions Original instructions cytiva.com...
Page 2: Table Of Contents
Remote control and data logging ................................... 87 5.3.5 Connect power ........................................88 5.3.6 Connect compressed air supply ..................................90 5.3.7 Connect external valves ..................................... 91 5.3.8 Connect external sensors ....................................92 5.3.9 Connect the drain ........................................95 AquaWIT V Operating Instructions 29748887 AB...
Page 3 Replacing Flowstar V ......................................203 Storage ........................................205 Biannual testing of the emergency stop functionality ......................208 Troubleshooting ..........................210 Self test ........................................211 Filter integrity test (FF/WIT/LT/FC) ..............................212 Bubble point test ....................................215 AquaWIT V Operating Instructions 29748887 AB...
Page 4 Contact information ......................................233 10.4.2 European Union and European Economic Area ............................234 10.4.3 Great Britain ..........................................235 10.4.4 North America ........................................236 10.4.5 South Korea ..........................................237 10.4.6 General regulatory statements ..................................238 Index ................................239 AquaWIT V Operating Instructions 29748887 AB...
Page 5: Introduction
This chapter contains information about this manual and associated user documentation, important user information, and intended use of the system. In this chapter Section See page Important user information About this manual Associated documentation Abbreviations AquaWIT V Operating Instructions 29748887 AB...
Page 6: Important User Information
Intended use of the product The AquaWIT V system is a filter integrity test instrument designed for testing the filter integrity of hydrophobic sterilizing-grade filters and hydrophilic membrane filters. The system also prepares the filter before and after the filter intergrity test.
Page 7: About This Manual
This manual provides information needed to install, operate, and perform maintenance in a safe way. Scope of this manual This manual is valid for the AquaWIT V system and covers the hardware and the software operations. The software operations are performed on screen of the Palltronic Flowstar V instrument. The illus- tration below shows the AquaWIT V system.
Page 8: Notes And Tips
Text that the user must either type exactly as shown in the manual, or that the software displays as a response (not a regular part of the graphic user interface), is shown by a monospaced typeface (for example, Recipe Information). Tip: The text can include clickable hyperlinks to reference information. AquaWIT V Operating Instructions 29748887 AB...
Page 9: Associated Documentation
1.3 Associated documentation Introduction This section describes the user documentation that is delivered with the product, and how to find related literature that can be downloaded or ordered from Cytiva. User documentation The user documentation is listed in the table below.
Page 10 Instructions for basic maintenance and trou- bleshooting. Access user documentation online Scan the QR code or visit cytiva.com/instructions. Enter the title or the document number to access the file. Regulatory support To subscribe to regulatory support documentation, visit to register at the http://www.cytiva.com/rsf...
Page 11: System Documentation
Select the type of document and download the chosen literature. System documentation In addition to the Operating Instructions manual, the documentation package supplied with AquaWIT V also includes product documentation binders that contains detailed specifications and traceability documents. Component documentation The documentations for third-party components are included in the document package.
Page 12: Abbreviations
AquaWIT V Operating Instructions 29748887 AB...
Page 13: Safety Instructions
All users must read and understand the entire contents of this general safety chapter, and the specific safety precau- tions information in each subsequent chapter of this manual to become aware of the hazards involved. AquaWIT V Operating Instructions 29748887 AB...
Page 14: Safety Precautions
2.1 Safety precautions 2.1 Safety precautions Introduction The AquaWIT V system is powered by mains voltage and handles materials that can be hazardous. Before installation, operation, or maintenance, you must be aware of the hazards described in this manual. Definitions This user documentation contains safety notices (WARNING, CAUTION, and NOTICE) concerning the safe use of the product.
Page 15 • damage caused by dropping the product, • damage caused by splashing liquid onto the product. WARNING Always use appropriate Personal Protective Equipment (PPE) during operation and maintenance of this product. AquaWIT V Operating Instructions 29748887 AB...
Page 16: Personal Protection
Always use appropriate Personal Protective Equipment (PPE) during operation and maintenance of this product. Flammable liquids and explosive environment WARNING Flammable liquids. This product is not approved for handling liquids under conditions when they can be flammable. AquaWIT V Operating Instructions 29748887 AB...
Page 17 2 Safety instructions 2.1 Safety precautions WARNING Explosion hazard. The product is not approved for use in a poten- tially explosive atmosphere. AquaWIT V Operating Instructions 29748887 AB...
Page 18: Labels And Symbols
The following symbols and text can be present on the nameplate: Symbol / text Description Follow instructions for use in the AquaWIT V Operating Instructions. Warning! Read the user documentation before using the system. Do not open any covers or replace parts unless specifically stated in the user docu- mentation.
Page 19: Safety Labels
The locations marked with this symbol conduct voltage even when the power switch is switched off. EMERGENCY STOP label. for further Section 2.3 Emergency procedures, on page 20 information regarding the emergency stop. AquaWIT V Operating Instructions 29748887 AB...
Page 20: Emergency Procedures
Pressurized flow path. If a condensate trap is installed, the system might remain pressurized. Make sure the system has cooled down and all lines and vessels are depressurized before resetting the EMERGENCY STOP button. AquaWIT V Operating Instructions 29748887 AB...
Page 21: Emergency Stop
Shock hazard. Do not use water to extinguish fire on or around the system. It can cause a fatal electrical shock. Emergency stop The emergency stop is a red button with yellow background. In this document the button is referred to as the EMERGENCY STOP button. AquaWIT V Operating Instructions 29748887 AB...
Page 22 2 Safety instructions 2.3 Emergency procedures Emergency stop button and power switch Part Function Power switch EMERGENCY STOP button AquaWIT V Operating Instructions 29748887 AB...
Page 23: Emergency Shutdown
• The air supply is not shut Note: down. The data from the ongoing run is lost and no test result file is generated as a result of switching off the power. AquaWIT V Operating Instructions 29748887 AB...
Page 24: Power Failure
Reset the EMERGENCY STOP button by twisting it clockwise (1) and then pulling it (2). Reset the emergency stop in the software. a. Tap the flashing button in the upper left corner of the HMI. b. Enter a comment. AquaWIT V Operating Instructions 29748887 AB...
Page 25 If a CIP or hot water sanitization procedure was interrupted, start the System Drain phase. • If a SIP procedure was interrupted, the System depressurisation phase starts auto- matically. Note: For drain instructions, see Section 7.6 Draining after aborted run, on page 150. AquaWIT V Operating Instructions 29748887 AB...
Page 26: System Description
3 System description 3 System description About this chapter This chapter provides an overview of the technical properties of the AquaWIT V system. In this chapter Section See page System overview Functional overview Illustrations System components Process flow diagram Accessories...
Page 27: System Overview
3.1 System overview Introduction The AquaWIT V system is a filter integrity test instrument designed for testing the filter integrity of hydrophobic sterilizing-grade filters and hydrophilic membrane filters. The system also prepares the filter before and after the filter intergrity test.
Page 28: Method Overview
Bubble point test (BP) • Combined forward flow and bubble point test (FF + BP) • Steaming-in-place (SIP) • Hot-water sanitization • Cleaning in place (CIP) For more information, see Section 3.2 Functional overview, on page AquaWIT V Operating Instructions 29748887 AB...
Page 29: Functional Overview
Before the FF test, the filter is wetted with water and flushed. During the test, the flow rate of gas across the membrane is measured. After the test, the filter is drained, and the water tank is automat- ically refilled with water. AquaWIT V Operating Instructions 29748887 AB...
Page 30 Before the test, the filter is wetted with water and flushed. After the test, the filter is drained, and the water tank is automatically refilled with water. AquaWIT V Operating Instructions 29748887 AB...
Page 31: Maintenance Procedures
Automated tank filling through the external water connection or the manual filling port. • Automated tank draining or draining through the manual drain valve. • Automated filter or system draining. • Automated system air flush. AquaWIT V Operating Instructions 29748887 AB...
Page 32: Illustrations
Flowstar V instrument and HMI Removable part of the top cover EMERGENCY STOP button Cable holder Piping cabinet Water tank Manual system drain valve Swivel casters with brake (4×) Hand rail Fill Tank indicator light AquaWIT V Operating Instructions 29748887 AB...
Page 33: Water Tank
Temperature sensor with a ¾ inch clamp Low water level switch (LSL04) Drain pipe with a ½ inch clamp Fixing screws (4×) Water tank High water level switch (LSH03) Lid clamp Manual filling port with a 1 ½ inch clamp AquaWIT V Operating Instructions 29748887 AB...
Page 34 Use the B-V spool piece and the A-G spool piece to perform a sanitization or cleaning procedure on the system. Do not use these spool pieces when an accessory is connected to the system. Use the V-G spool piece to perform a sanitization or cleaning procedure when an accessory is connected to the system. AquaWIT V Operating Instructions 29748887 AB...
Page 35: Connector Panels
Bypass air outlet port CAN bus port (typically used for connecting to MUX or Flush Set) AIR IN Air inlet port AIR OUT Air outlet port IO LINK1 I/O communication port 1 for external sensors AquaWIT V Operating Instructions 29748887 AB...
Page 36 System drain port with a ½ inch clamp Power supply socket Power box For instructions, refer to the Flowstar V Printer Instructions for Use (29750853). AquaWIT V Operating Instructions 29748887 AB...
Page 37 203. The connector panels on the Flowstar V instrument are shown to facilitate this replacement procedure. During normal operation of the AquaWIT V system, always use the connectors on the AquaWIT V system not the connectors on the Flowstar V instrument.
Page 38 Part Label Description CAN bus port (connected to the AquaWIT V base unit) Air inlet port (connected to the AquaWIT V base unit) EXT VALVE External vent valve port (connected to the left side of the...
Page 39 The connectors on this panel are not accessible, except when the Flowstar V instrument is removed from the system. Part Description Power switch (connected to the back of the AquaWIT V system) Power cord Vent port AquaWIT V Operating Instructions 29748887 AB...
Page 40: System Components
This section provides descriptions of the system and an overview of all components, including the control system. For further details and specifications, refer to the documentation package provided with the delivery. In this section Section See page 3.4.1 Water tank 3.4.2 Piping cabinet 3.4.3 Valves 3.4.4 Sensors AquaWIT V Operating Instructions 29748887 AB...
Page 41: Water Tank
After a run, or during maintenance, all tank components can be disassembled and the tank can be lifted out of the assembly. For detailed instructions, see Clean the water tank, on page 171. AquaWIT V Operating Instructions 29748887 AB...
Page 42: Piping Cabinet
The illustration below shows the parts inside the piping cabinet on the back of the system. Part Definition Control box Valves AV01 to AV05 Level switch LSH01 Level switch LSH05 Level switch LSH02 Measurement chamber (between LSH01 and LSH02) AquaWIT V Operating Instructions 29748887 AB...
Page 43 3 System description 3.4 System components 3.4.2 Piping cabinet Part Definition Valves AV06 to AV09, and AV14 Pressure transmitter PT01 Power box AquaWIT V Operating Instructions 29748887 AB...
Page 44: Valves
The system can connect up to six external valves. These valves can be used during a process run, see Section 5.3.7 Connect external valves, on page Section 7.3.1 Connect a filter, on page 117 Section 7.4.1 Connect a filter, on page 128. AquaWIT V Operating Instructions 29748887 AB...
Page 45: Sensors
LSH01, LSH02 and LSH05 The temperature sensor is installed on the water tank. The sensor meas- ures the actual temperature. The temperature value is indicated on the HMI. TT01 AquaWIT V Operating Instructions 29748887 AB...
Page 46: External Sensors
The following sensors are validated for use with the system: • The Anderson-Negele P42 pressure sensor • The Anderson-Negele TSMP temperature sensor • The Labom CA1510 pressure sensor • The Labom GA2730 temperature sensor AquaWIT V Operating Instructions 29748887 AB...
Page 47: Process Flow Diagram
LSH-05 LSH-03 TT-01 LSL-04 AV-06 AV-08 AV-14 AV-07 AV-09 For the process flow diagram of the setup including the MUX or the Flush Set, refer to the respective Instructions for Use of the accessory. AquaWIT V Operating Instructions 29748887 AB...
Page 48 Symbol Description Normally open valve Normally closed valve Normally closed valve, with a manual handle Water tank Sensor Pressure sensor Temperature sensor Low level switch High level switch Optional condensate trap AquaWIT V Operating Instructions 29748887 AB...
Page 49: Accessories
3.6 Accessories Introduction This section gives a brief description of the accessories that can be used with the AquaWIT V system. Previous generation accessories can be connected to the AquaWIT V system, but a software modifi- cation is necessary. Contact your local Cytiva representative for support.
Page 50: Other Accessories
Anderson-Negele A communication cable for external temperature and pressure sensors sensor kit D from Anderson-Negele that are I/O-Link capable. Delivered with the Flush Set extension and the MUX extension. Delivered with the MUX extension. AquaWIT V Operating Instructions 29748887 AB...
Page 51: Human Machine Interface
4 Human machine interface 4 Human machine interface About this chapter This chapter provides an overview of the human machine interface (HMI) of the AquaWIT V system. In this chapter Section See page Control system Software settings AquaWIT V Operating Instructions 29748887 AB...
Page 52: Control System
The system is controlled from the HMI on the integrated Flowstar V instrument. The control software is part of the configuration provided with the system. The Flowstar V instrument communicates with the control units within the AquaWIT V base unit, and the accessories via a CAN bus connection.
Page 53 AquaWIT V software settings The software settings for the AquaWIT V system are located in Tools →AquaWIT Configuration. The default settings are selected after enabling the AquaWIT V system in the software (see Enable AquaWIT V in software, on page 103).
Page 54: User Authority Levels
Section 4.2 Software settings, on page User authority levels The following table describes the user access authority the specific functions for the AquaWIT V system. For details about the general user access authority of the software, refer to the Palltronic Flowstar V Integrity Test Instrument Operating Instructions.
Page 55: Test Programs
Active extension. • If the AquaWIT V is enabled when a test program is created, test parameters for Flowstar V and AquaWIT V are set. When the test program is accessed when the AquaWIT V is disabled, the soft- ware loads only the test program parameters that are valid for the Flowstar V instrument.
Page 56: Software Settings
Section See page 4.2.1 Introduction 4.2.2 System software settings 4.2.3 Water tank and flow path settings 4.2.4 Filter settings 4.2.5 BP and FF settings 4.2.6 WIT settings 4.2.7 External sensor settings 4.2.8 Maintenance settings AquaWIT V Operating Instructions 29748887 AB...
Page 57: Introduction
4.2.1 Introduction 4.2.1 Introduction This section describes the software settings for the AquaWIT V system. Other software settings are described in the Palltronic Flowstar V Integrity Test Instrument Operating Instructions. Note: In the General Settings the unit for temperature can be set to use degrees Celsius or Fahrenheit, and the unit for pressure can be set to mbar, psi, kp/cm or kPa.
Page 58: System Software Settings
When using an external water source, the pressure of the water supply must be reduced to below 3 bar (43.5 psi) and the temperature must be between 18°C to 24°C (64 to 77°F). The system does not monitor the water temperature before a filter test starts. AquaWIT V Operating Instructions 29748887 AB...
Page 59: Water Tank And Flow Path Settings
Select the default maximum pressure to drain the water tank and piping. system pressure This setting is used in the following phases: • Drain system • Drain tank • System cleaning • Hot water sanitization AquaWIT V Operating Instructions 29748887 AB...
Page 60 Select the default maximum time to drain the water tank and piping. This system timeout setting is used in the following phases: • Drain system • Drain tank • System cleaning • Hot water sanitization AquaWIT V Operating Instructions 29748887 AB...
Page 61: Filter Settings
Medium or High, there is a risk of overfilling the system or incorrect calculation of hydrostatic pressure due to applying overpressure. Contact Cytiva for support with specific filter installations that require deviations to the recommended settings.
Page 62 AquaWIT IV system. Now the maximum allowed pressure is defined in the soft- ware. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 63: Bp And Ff Settings
Default soak/flush cycles number of times: • Filter filling • Filter soaking • Filter flushing Suggestions for wetting parameters are described in the Successful wetting for filter integrity testing in volume-restricted systems Application Note (USD3000). AquaWIT V Operating Instructions 29748887 AB...
Page 64: Wit Settings
Default filter air Select the default time for the air flush sequence. flush time AquaWIT V Operating Instructions 29748887 AB...
Page 65: External Sensor Settings
Leaving this field empty, removes the threshold. Upper Bound Select the upper threshold signal from the external sensor that is accepted for a successful run. Leaving this field empty, removes the threshold. AquaWIT V Operating Instructions 29748887 AB...
Page 66: Maintenance Settings
Select to lock or unlock the sanitization settings. Options are: • Yes: The sanitization setting can only be edited by going to Tools →AquaWIT Configuration. • No: The sanitization setting can be edited for each sanitization run. AquaWIT V Operating Instructions 29748887 AB...
Page 67 If the timer reaches Sanitization reset time, Sanitisation time is reset to 0. If Sanitisation reset timer is activated during a successful sanitization run, a Temperature drop detected warning is included in the result file. AquaWIT V Operating Instructions 29748887 AB...
Page 68: Installation
AquaWIT V system. In addition, instructions are included for moving the system within the room or to another building. In this chapter Section See page Safety precautions Site preparation Install the system Moving the system AquaWIT V Operating Instructions 29748887 AB...
Page 69: Safety Precautions
WARNING Personal Protective Equipment (PPE). When packing, unpacking, transporting or moving the product, wear the following: • Protective footwear, preferably with steel toe caps. • Working gloves, protecting against sharp edges. AquaWIT V Operating Instructions 29748887 AB...
Page 70: Site Preparation
This section describes the site planning and preparation that must be performed before the product is installed. Refer also to the Site Preparation Guide. In this section Section See page 5.2.1 Delivery, storage and unpacking 5.2.2 Room requirements 5.2.3 Site environmental requirements 5.2.4 Power requirements 5.2.5 Media supply AquaWIT V Operating Instructions 29748887 AB...
Page 71: Delivery, Storage And Unpacking
For information on how to receive and store the delivery box, and to unpack the instrument, refer to the AquaWIT V Unpacking Instructions that is attached on the crate. It is also available on the web. At least two people are required to unpack the crate in a safe way.
Page 72: Storage Requirements
Ambient temperature, storage 25% to 80%, non-condensing Relative humidity Transportation The following equipment is needed for handling the crate: Equipment Specifications Pallet mover Suitable for a pallet 80 × 120 cm of up to 300 kg AquaWIT V Operating Instructions 29748887 AB...
Page 73: Unpacking The System
5.2.1 Delivery, storage and unpacking Unpacking the system For information on how to unpack the system refer to the separate AquaWIT V Unpacking Instruc- tions. Save all the original packing material. If the system has to be repacked, for transportation or other- wise, it is important that the system can be safely packed using the original packing material.
Page 74: Room Requirements
Make sure that sufficient space is provided on all sides of the system when it is installed at the intended location. Consider the inlet lines, the outlet lines, the connections to a filter and/or accessories. AquaWIT V Operating Instructions 29748887 AB...
Page 75: Site Environmental Requirements
Dust in the atmosphere must be kept to a minimum. Instrument ventilation There must be at least 10 cm clearance around the instrument to allow adequate air circulation. NOTICE Do not block the air vents on the equipment. AquaWIT V Operating Instructions 29748887 AB...
Page 76: Heat Output
5 Installation 5.2 Site preparation 5.2.3 Site environmental requirements Heat output The heat output data is listed in the table below. Component Heat output AquaWIT V system Typically 150 W Maximum 1200 W (SIP) AquaWIT V Operating Instructions 29748887 AB...
Page 77: Power Requirements
Electrical power requirements The following table specifies the power requirements for the system. Parameter Requirement Supply voltage 100 to 240 VAC Frequency 50/60 Hz Power outlet type Grounded mains outlets Transient overvoltages Overvoltage category II AquaWIT V Operating Instructions 29748887 AB...
Page 78: Power Quality
The isolation switch must always be easy to access. • The system power cable is connected with an industrial power plug, compliant with national codes and standards. Note: The power plug must always be easy to disconnect. AquaWIT V Operating Instructions 29748887 AB...
Page 79: Grounding And Protective Earth
Where the protective conductor is part of a multi-conductor power cable, with a cross- sectional area of not less than 2.5 mm More information The documentation package delivered with AquaWIT V includes the following information: • Wiring diagrams for the system •...
Page 80: Media Supply
Media supply Media supply Description Compressed air Oil and particle free, non-condensing air or nitrogen gas (according to ISO 8573-1:2010 Class 3.4.4 or better) Water Water for injection (WFI) or deionized water Steam Saturated steam AquaWIT V Operating Instructions 29748887 AB...
Page 81: Install The System
Connect to a network location or a printer 5.3.4 Remote control and data logging 5.3.5 Connect power 5.3.6 Connect compressed air supply 5.3.7 Connect external valves 5.3.8 Connect external sensors 5.3.9 Connect the drain 5.3.10 Performance test AquaWIT V Operating Instructions 29748887 AB...
Page 82: Safety Precautions
Protective ground. The product must be connected to a grounded power outlet. NOTICE Electrical damage. Do not disconnect electrical or network connections during a run. It can cause damage to the electronic components in the system. AquaWIT V Operating Instructions 29748887 AB...
Page 83: Position The System
Access to power switch and power cord. The power switch must always be easy to access. The power cord must always be easy to disconnect. Lock the casters After positioning the system at its designated location, lock the casters as illustrated below. AquaWIT V Operating Instructions 29748887 AB...
Page 84: Connect To A Network Location Or A Printer
Action Connect an Ethernet cable to the Ethernet port (2) on the back of the system. Connect the other end of the Ethernet cable to a router or remote computer. Go to Tools →Network. AquaWIT V Operating Instructions 29748887 AB...
Page 85 Connect Flowstar V Printer to the printer port (3) on the back of the system. Note: For detailed instructions, refer to the Palltronic Flowstar V Integrity Test Instrument Operating Instructions and Flowstar V Printer Instructions for Use (29750853). AquaWIT V Operating Instructions 29748887 AB...
Page 86 Set the printer parameters. • To print a test program, refer to the Palltronic Flowstar V Integrity Test Instrument Operating Instructions. • To print a result file, see Access result files, on page 159. AquaWIT V Operating Instructions 29748887 AB...
Page 87: Remote Control And Data Logging
PAS-X for Flowstar V User Manual (29741432) PROFIBUS Remote control of Palltronic Flowstar V integrity test instrument using the PROFIBUS protocol (USD3924) PROFINET Remote control of Palltronic Flowstar V integrity test instrument using the PROFINET protocol (USD3934) AquaWIT V Operating Instructions 29748887 AB...
Page 88: Connect Power
The power cord is correctly connected when the power plug snaps into place, and makes an audible click sound. e. Pull the other end of the power cord through the hole in the bottom of the piping cabinet (2). AquaWIT V Operating Instructions 29748887 AB...
Page 89 When the instrument is disconnected from power, hang the power cord on the cable holder. Press the l position on the power switch. NOTICE Do not switch on the power switch before all connections are made. AquaWIT V Operating Instructions 29748887 AB...
Page 90: Connect Compressed Air Supply
Stäubli RBE03 female connector. NOTICE Contamination risk. Only use pneumatic tubing and connections that are clean, dry, and free from any fluids or contaminants. Valves can malfunction when contaminated with liquid or oil. AquaWIT V Operating Instructions 29748887 AB...
Page 91: Connect External Valves
The external valves must be installed on the filter housing and connected to the system to test filters that are installed in-line with a processing line. Go to Tools →AquaWIT Manual Operation, then open and close each installed external valve to verify the valve actuation. AquaWIT V Operating Instructions 29748887 AB...
Page 92: Connect External Sensors
Go to Tools →AquaWIT Configuration and set the external sensor type to Pressure or Temperature. • For external sensor 1, set the sensor type for AquaWIT Ext Sensor 1 Type. • For external sensor 1, set the sensor type for AquaWIT Ext Sensor 2 Type. AquaWIT V Operating Instructions 29748887 AB...
Page 93 Lower bound and Upper bound at the beginning of a filter test, the HMI displays the pop-up warning message External sensor 1 / external sensor 2 outside range. To continue the run, tap Confirm. To abort the run, tap Abort. AquaWIT V Operating Instructions 29748887 AB...
Page 94 Do not change the AquaWIT Ext Sensor 1 / 2 Type parameter in the software during a run. If an external sensor is disconnected during a method run, the run aborts and displays the warning External sensor 1 / external sensor 2 outside range in the test result. AquaWIT V Operating Instructions 29748887 AB...
Page 95: Connect The Drain
Place or connect the other end of the hose to the waste drain. Note: • The hose must have a downward slope from the outlet to the drain. • The drain must have atmospheric pressure and must not have any back pressure. AquaWIT V Operating Instructions 29748887 AB...
Page 96: Performance Test
5.3.10 Performance test 5.3.10 Performance test Before taking the AquaWIT V system into use, run a Self Test to check the function of the system. Refer to the Palltronic Flowstar V Integrity Test Instrument Operating Instructions for instructions. AquaWIT V Operating Instructions 29748887 AB...
Page 97: Moving The System
The center of gravity of the product is high and the product may tip over if the forks are offset too far to either side. AquaWIT V Operating Instructions 29748887 AB...
Page 98 Use the original transport crate, or secure the system to the pallet jack or fork lift. For minimum door aperture size requirements and center of gravity for transporting the system after unpacking, refer to the General Arrangement provided with the system. AquaWIT V Operating Instructions 29748887 AB...
Page 99 If applicable, connect the system to the filter. If applicable, connect the system to an extension, an accessory, a printer, and a network. (Recommended) Test the system performance by running a Self Test. AquaWIT V Operating Instructions 29748887 AB...
Page 100: Preparation
6 Preparation 6 Preparation About this chapter This chapter gives the required information to prepare the AquaWIT V system for operation. In this chapter Section See page Safety precautions Starting the system Preparing the water tank Filter cooling AquaWIT V Operating Instructions 29748887 AB...
Page 101: Safety Precautions
The wheels of the product must be locked during normal use. The wheels must be unlocked only when moving the product. CAUTION Make sure that the common waste outlet is never exposed to back- pressure. AquaWIT V Operating Instructions 29748887 AB...
Page 102 NOTICE The wetted parts of the product may be damaged by certain chemi- cals. Contact your Cytiva representative before using chemicals that are not listed in the chemical resistance information. NOTICE Electrical damage. Do not disconnect electrical or network connections during a run.
Page 103: Starting The System
Follow the instructions below to start the AquaWIT V system. Step Action On the back of the AquaWIT V system, press the l position on the power switch. On the right side of the HMI, press the power button. Enter your user name and password on the HMI.
Page 104 6 Preparation 6.2 Starting the system Step Action Select AquaWIT V from the Active extension drop-down list. AquaWIT V Operating Instructions 29748887 AB...
Page 105: Preparing The Water Tank
Tap Fill tank. b. Enter the Operator. c. Select Via Port C in the Water source drop-down list. Remove the blank TC-cap to open the filling port C. Place a funnel into the filling port C. AquaWIT V Operating Instructions 29748887 AB...
Page 106 Make sure that the water supply follows the minimum specifications, see Process oper- ating limits, on page 227. Note: Do not exceed the water pressure, because it can cause the tank to be filled above the recommended volume. Select the setting in the software: AquaWIT V Operating Instructions 29748887 AB...
Page 107 When LSH03 indicates Full status in the HMI, the volume in the tank is approxi- mately 16 L. • When the water level is higher than LSL04, the water level indicator on the front of the system switches off. Disconnect the water supply from inlet port E. AquaWIT V Operating Instructions 29748887 AB...
Page 108: Filter Cooling
Section 7.3.1 Connect a filter, on page 117 to connect a filter that needs to be cooled by the system. Start a filter cooling run Follow the steps below to start a filter cooling run. Step Action Tap Cool Filter. AquaWIT V Operating Instructions 29748887 AB...
Page 109 When using an external water source, the pressure of the water supply must be reduced to below 3 bar (43.5 psi) and the temperature must be between 18°C to 24°C (64 to 77°F). The system does not monitor the water temperature before a filter test starts. AquaWIT V Operating Instructions 29748887 AB...
Page 110 Filter Pressure that were available in the software for the AquaWIT IV system. Now the maximum allowed pressure is defined in the software. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 111 1. The system fills the filter with water from the water tank or from the (optional) external water supply. 2. The system is idle for the Cool filter time. 3. The system drains the filter. AquaWIT V Operating Instructions 29748887 AB...
Page 112: Operation
7 Operation 7 Operation About this chapter This chapter gives instructions on how to operate AquaWIT V in safe way. In this chapter Section See page Safety precautions Before starting a run Test a hydrophobic filter Test a hydrophilic filter...
Page 113: Safety Precautions
Overpressure. Make sure that the test pressure is less than the maximum operating pressure that is specified for the filter housing or the filter capsule. The filter can explode at overpressure and cause injury. AquaWIT V Operating Instructions 29748887 AB...
Page 114 NOTICE The wetted parts of the product may be damaged by certain chemi- cals. Contact your Cytiva representative before using chemicals that are not listed in the chemical resistance information. NOTICE Electrical damage. Do not disconnect electrical or network connections during a run.
Page 115: Before Starting A Run
The caster wheels are locked. Note: Do not remove the top cover during a run. Do not operate the AquaWIT V system without the top cover in place. Do not operate a filter integrity test with the maintenance manifolds installed.
Page 116: Test A Hydrophobic Filter
This section describes how to run the water intrusion test (WIT) on hydrophobic filters, using the system. In this section Section See page 7.3.1 Connect a filter 7.3.2 Start a WIT run 7.3.3 During a WIT run AquaWIT V Operating Instructions 29748887 AB...
Page 117: Connect A Filter
Connect a flexible hose to inlet port B. d. Connect the other end of the hose to the drain port (bottom) of the filter housing. e. Connect a flexible hose to inlet port G. AquaWIT V Operating Instructions 29748887 AB...
Page 118 (Optional) Connect the external valves. Note: The external valves must be installed on the filter housing and connected to the system to test filters that are installed in-line with a processing line. AquaWIT V Operating Instructions 29748887 AB...
Page 119 For detailed instructions, see Section 5.3.8 Connect external sensors, on page Note: → AquaWIT Manual To see the output of the external sensors, go to Tools Operation. AquaWIT V Operating Instructions 29748887 AB...
Page 120 7.3 Test a hydrophobic filter 7.3.1 Connect a filter Step Action WARNING Overpressure. Make sure that filter housing is vented and is at atmospheric pressure before dismantling of the filter assembly. Overpressure can result in injury. AquaWIT V Operating Instructions 29748887 AB...
Page 121: Start A Wit Run
• Production area • Filter line • Filter housing • any user defined fields Follow the steps below to start a WIT run after setting the parameters manually. Step Action Tap Water Intrusion. AquaWIT V Operating Instructions 29748887 AB...
Page 122 When using an external water source, the pressure of the water supply must be reduced to below 3 bar (43.5 psi) and the temperature must be between 18°C to 24°C (64 to 77°F). The system does not monitor the water temperature before a filter test starts. AquaWIT V Operating Instructions 29748887 AB...
Page 123 1250 mbar (18.1 psi). Fill filter timeout Time in seconds Select the maximum time for filling the filter housing. Calculate the time depending on the water supply pressure, filter height, and filter size. AquaWIT V Operating Instructions 29748887 AB...
Page 124 Filter Pressure that were available in the software for the AquaWIT IV system. Now the maximum allowed pressure is defined in the software. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 125: During A Wit Run
PT01, and the system compensates if the filter is installed higher than the system. If the pressure reading is unstable, the system aborts the test and displays the HYDROSTATIC HEAD UNSTABLE error in the test results. AquaWIT V Operating Instructions 29748887 AB...
Page 126 2. The test results can be printed. The printout shows the test parame- ters, the date, the time, and the test result. Empty parameter fields are not printed. AquaWIT V Operating Instructions 29748887 AB...
Page 127: Test A Hydrophilic Filter
Section See page 7.4.1 Connect a filter 7.4.2 Run a forward flow test 7.4.3 Run a bubble point test 7.4.4 Run a combined forward flow and bubble point test 7.4.5 During a FF/BP/FF+BP run AquaWIT V Operating Instructions 29748887 AB...
Page 128: Connect A Filter
Connect a flexible hose to inlet port G. f. Connect the other end of the hose to the downstream side (bottom) of the filter housing. Note: If no external valves are connected, make sure that valve AV14 is connected. AquaWIT V Operating Instructions 29748887 AB...
Page 129 (AV10, AV11, AV12, AV15). Select the air hose diam- eter depending on the requirement of the valve. b. Connect the other end of the air hose to the respective valve. AquaWIT V Operating Instructions 29748887 AB...
Page 130 To see the output of the external sensors, go to Tools Operation. WARNING Overpressure. Make sure that filter housing is vented and is at atmospheric pressure before dismantling of the filter assembly. Overpressure can result in injury. AquaWIT V Operating Instructions 29748887 AB...
Page 131: Run A Forward Flow Test
• Production area • Filter line • Filter housing • any user defined fields Follow the steps below to start a FF run after setting the parameters manually. Step Action Tap Forward flow test. AquaWIT V Operating Instructions 29748887 AB...
Page 132 When using an external water source, the pressure of the water supply must be reduced to below 3 bar (43.5 psi) and the temperature must be between 18°C to 24°C (64 to 77°F). The system does not monitor the water temperature before a filter test starts. AquaWIT V Operating Instructions 29748887 AB...
Page 133 High The pressure adjustment for filling and draining is set to 1250 mbar (18.1 psi). Use this setting for a filter that are installed up to 5 m above the system. AquaWIT V Operating Instructions 29748887 AB...
Page 134 Filter Pressure that were available in the software for the AquaWIT IV system. Now the maximum allowed pressure is defined in the software. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 135 Yes. • During a run or when a run is aborted, a pressure release sound can be heard briefly. The sound originates from venting the piping or the water tank. AquaWIT V Operating Instructions 29748887 AB...
Page 136: Run A Bubble Point Test
• Production area • Filter line • Filter housing • any user defined fields Follow the steps below to start a BP run after setting the parameters manually. Step Action Tap Bubble Point. AquaWIT V Operating Instructions 29748887 AB...
Page 137 When using an external water source, the pressure of the water supply must be reduced to below 3 bar (43.5 psi) and the temperature must be between 18°C to 24°C (64 to 77°F). The system does not monitor the water temperature before a filter test starts. AquaWIT V Operating Instructions 29748887 AB...
Page 138 High The pressure adjustment for filling and draining is set to 1250 mbar (18.1 psi). Use this setting for a filter that are installed up to 5 m above the system. AquaWIT V Operating Instructions 29748887 AB...
Page 139 Filter Pressure that were available in the software for the AquaWIT IV system. Now the maximum allowed pressure is defined in the software. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 140 Yes. • During a run or when a run is aborted, a pressure release sound can be heard briefly. The sound originates from venting the piping or the water tank. AquaWIT V Operating Instructions 29748887 AB...
Page 141: Run A Combined Forward Flow And Bubble Point Test
Production area • Filter line • Filter housing • any user defined fields Follow the steps below to start a FF + BP run after setting the parameters manually. Step Action Tap FF + BP. AquaWIT V Operating Instructions 29748887 AB...
Page 142 When using an external water source, the pressure of the water supply must be reduced to below 3 bar (43.5 psi) and the temperature must be between 18°C to 24°C (64 to 77°F). The system does not monitor the water temperature before a filter test starts. AquaWIT V Operating Instructions 29748887 AB...
Page 143 High The pressure adjustment for filling and draining is set to 1250 mbar (18.1 psi). Use this setting for a filter that are installed up to 5 m above the system. AquaWIT V Operating Instructions 29748887 AB...
Page 144 Filter Pressure that were available in the software for the AquaWIT IV system. Now the maximum allowed pressure is defined in the software. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 145 Yes. • During a run or when a run is aborted, a pressure release sound can be heard briefly. The sound originates from venting the piping or the water tank. AquaWIT V Operating Instructions 29748887 AB...
Page 146: During A Ff/Bp/Ff+Bp Run
2. The filter housing drains to port F and the filter membrane is wetted. 3. The sequence is repeated from filter filling a number of times equal to the selection in the test inputs. AquaWIT V Operating Instructions 29748887 AB...
Page 147 2. The test results can be printed. The printout shows the test parame- ters, the date, the time, and the test result. Empty parameter fields are not printed. AquaWIT V Operating Instructions 29748887 AB...
Page 148: Manual Run
This section describes how to start a manual run using the system. Start a manual run NOTICE Manual operation of the system must only be performed by trained and experienced personnel. Follow the steps below to start a manual run. Step Action Tap Tools. AquaWIT V Operating Instructions 29748887 AB...
Page 149 Step Action Tap AquaWIT Manual Operation. Result: The piping and instrument diagram is shown. Tap a valve and select to open or close it. View the measured values from the temperature and pressure sensor. AquaWIT V Operating Instructions 29748887 AB...
Page 150: Draining After Aborted Run
This section describes how to drain the filter, system, or water tank after an operation is aborted due to an error, an emergency stop, or a manual abort. In this section Section See page 7.6.1 Draining options 7.6.2 Drain the filter 7.6.3 Drain the system 7.6.4 Drain the water tank AquaWIT V Operating Instructions 29748887 AB...
Page 151: Draining Options
Section 7.6.3 Drain the • After an aborted cleaning-in-place, system, on page 155. steaming in place, or a hot water sanitization procedure. • The level switches LSH01, LSH02, LSH03, LSL04, or LSH05 indicate the FULL status AquaWIT V Operating Instructions 29748887 AB...
Page 152: Drain The Filter
The sequence works identical to the drain filter phase of a WIT test. Start draining the filter Follow the steps below to drain the filter. Step Action Tap Drain Filter. AquaWIT V Operating Instructions 29748887 AB...
Page 153 Filter Pressure that were available in the software for the AquaWIT IV system. Now the maximum allowed pressure is defined in the software. The AquaWIT V system does not use a pressure controller. The Fill / drain filter pressure level setting controls the speed and interval of the pressure bursts that are used to fill or drain the filter.
Page 154 Action Tap the button. Note: If you tap the button to return to the Main menu, the selected parameters are not saved. Result: An overview of the test parameters is shown. Tap the button. AquaWIT V Operating Instructions 29748887 AB...
Page 155: Drain The System
Parameter Setting Description Drain system timeout Time in seconds Select the default maximum time to drain the system. Drain system pressure Pressure in mbar Select the default maximum pressure to drain the system. AquaWIT V Operating Instructions 29748887 AB...
Page 156 7.6 Draining after aborted run 7.6.3 Drain the system Step Action Return to the Main Menu, and tap Drain System. Tap the button. Result: An overview of the test parameters is shown. Tap the button. AquaWIT V Operating Instructions 29748887 AB...
Page 157: Drain The Water Tank
Time in seconds Select the default maximum time to drain the system. Drain system pressure Pressure in mbar Select the default maximum pressure to drain the system. Return to the Main Menu, and tap Drain Tank. AquaWIT V Operating Instructions 29748887 AB...
Page 158 AV07 and AV09 valves open. Water in the water tank drains to waste through port F. 3. The system detects the breakthrough of air after all liquid is drained from the drain piping and continues with a few pressure bursts to remove larger water droplets. AquaWIT V Operating Instructions 29748887 AB...
Page 159: After Run Procedures
Tap the test type to filter the test results for the relevant test type. Select a test type from the following options: • Forward Flow (FF) • Bubble Point (BP) • Combined Forward Flow and Bubble Point (FF/BP) AquaWIT V Operating Instructions 29748887 AB...
Page 160 To transfer the test result, refer to the Palltronic Flowstar V Integrity Test Instrument Operating Instructions. To add an electronic signature, select the relevant test result file and tap Sign. Note: Activate the electronic signature function for the relevant user in the Access Management menu. AquaWIT V Operating Instructions 29748887 AB...
Page 161: Shut Down The System
On the right side of the HMI, press the power button. On the back of the AquaWIT V system, press the O position on the power switch. Before maintenance or disconnecting pipes, tag the AquaWIT V system as taken out of operation.
Page 162: Maintenance
8 Maintenance 8 Maintenance About this chapter This chapter provides information about maintenance that must be performed by users of AquaWIT V. A list of planned maintenance actions is presented in this chapter. In this chapter Section See page Safety precautions...
Page 163: Safety Precautions
Only personnel authorized by Cytiva may perform service and maintenance of the product. WARNING Use only approved parts. Only spare parts and accessories that are approved or supplied by Cytiva can be used for maintaining or servicing the product. WARNING Always use appropriate Personal Protective Equipment (PPE) during operation and maintenance of this product.
Page 164: Service And Preventive Maintenance
Service Engineer starts a repair. To avoid delays in the servicing of your equipment, complete the Cytiva service check- list and present it to the Service Engineer upon arrival. Equipment and/or work areas not sufficiently cleaned, accessible and safe for an engineer may lead to delays in servicing the equipment and could be subject to additional charges.
Page 165: User Maintenance Schedule
The most recent calibration date and the servicing date are stored on the Flowstar V instru- ment. For maintenance work not described in this manual, contact your Cytiva representative. Maintenance in connection to each run or weekly The table below lists the maintenance actions required for each run, or weekly, depending on which happens first.
Page 166: Monthly Maintenance
171. Maintenance annually or as needed A preventive maintenance test procedure on all components, sensors, and valves must be performed annually by trained and certified personnel. Contact your local Cytiva representative. AquaWIT V Operating Instructions 29748887 AB...
Page 167: Cleaning
In this section Section See page 8.4.1 Safety precautions 8.4.2 General cleaning 8.4.3 Cleaning components 8.4.4 Before you start a sanitization run 8.4.5 Cleaning-in-place (CIP) 8.4.6 Hot water sanitization 8.4.7 Steaming-in-place (SIP) 8.4.8 Air flush AquaWIT V Operating Instructions 29748887 AB...
Page 168: Safety Precautions
WARNING Leakage risk. Make sure that an operator remains close to the system during automated maintenance (e.g. CIP or SIP) to solve any problems that might occur, such as unintended leakage. AquaWIT V Operating Instructions 29748887 AB...
Page 169 The system is not compatible with all CIP solutions. Only use the CIP solutions that are described in the user documentation. NOTICE The filter may not be compatible with the CIP solutions. Follow the instructions provided by the filter manufacturer. AquaWIT V Operating Instructions 29748887 AB...
Page 170: General Cleaning
EPDM. Rinse the system thoroughly with water immediately after it has been in contact with salt solutions. Cleaning agents must be disposed of according to national and local environmental regulations. AquaWIT V Operating Instructions 29748887 AB...
Page 171: Cleaning Components
Step Action Verify on the manometer display that the pressure in the water tank is released. Unplug the M12 sensor cable plugs from the LSH03, LSL04, and TT01 sensors. AquaWIT V Operating Instructions 29748887 AB...
Page 172 Unscrew the two fixing screws (1) on the feet of the water tank that are at the back. c. While holding the tank in place on the handles, slide the water tank towards the front of the system. AquaWIT V Operating Instructions 29748887 AB...
Page 173 Remove manometer from the lid, and the sensors from the water tank. Remove the lid from the water tank. a. Open and remove the lid clamp of the tank lid. b. Remove the tank lid from the water tank. AquaWIT V Operating Instructions 29748887 AB...
Page 174 Place the tank lid on the water tank, then align the tank lid with the water tank. Make sure that the thin engraved lines on the tank flange and on the tank lid are aligned. AquaWIT V Operating Instructions 29748887 AB...
Page 175 Swing the bolts on the lid clamp into the fork. Then, bring them into position. Tip: Use grease between the threaded bolts and nuts on the lid clamp. Tighten the nuts lightly. Make sure that the gaps between the segments are equal. AquaWIT V Operating Instructions 29748887 AB...
Page 176 Repeat this tightening process until the required torque is reached on both nuts. Install all components, gaskets and the tank in the reverse order as described in Clean the water tank, on page 171. AquaWIT V Operating Instructions 29748887 AB...
Page 177: Before You Start A Sanitization Run
Do not remove the top cover during a run. Do not operate the system without the top cover in place. Install the maintenance manifolds Follow the steps below to install the maintenance manifolds. Step Action Verify on the manometer display that the pressure in the flow path is released. AquaWIT V Operating Instructions 29748887 AB...
Page 178 8.4.4 Before you start a sanitization run Step Action Install the spool piece between port B and port V. Tip: The illustration in Maintenance manifold, on page 34 shows the three spool pieces of the maintenance manifold. AquaWIT V Operating Instructions 29748887 AB...
Page 179 8 Maintenance 8.4 Cleaning 8.4.4 Before you start a sanitization run Step Action Install the spool piece between port A and port G. AquaWIT V Operating Instructions 29748887 AB...
Page 180: Cleaning-In-Place (Cip)
Action Prepare the flow path. a. Install the maintenance manifolds, see Section 8.4.4 Before you start a sanitization run, on page 177. b. Connect port E to the supply line of the cleaning agent. AquaWIT V Operating Instructions 29748887 AB...
Page 181 Use the supplied TC-clamps with hexagonal heads to fasten the connections to the system for maintenance procedures. Tighten the TC-clamps with a wrench and check each connection individually before running the maintenance procedure. Tap Clean System. AquaWIT V Operating Instructions 29748887 AB...
Page 182 Number of rinse cycles Integer Select the number of refilling cycles during the rinsing phase. Note: The phases of a CIP procedure can be repeated up to ten times. AquaWIT V Operating Instructions 29748887 AB...
Page 183 Cleaning fluid min temperature setting. If the tempera- ture is below the threshold, an warning pop-up message is displayed on the screen. To continue the run, tap Confirm. To abort the run, tap Abort. AquaWIT V Operating Instructions 29748887 AB...
Page 184 CIP. Rinsing After completed CIP, make sure to rinse the system flow path and all cleaned components thor- oughly to remove all traces of the cleaning agent. AquaWIT V Operating Instructions 29748887 AB...
Page 185: Hot Water Sanitization
Note: Use the supplied TC-clamps with hexagonal heads to fasten the connections to the system for maintenance procedures. Tighten the TC-clamps with a wrench and verify each connection individually before running the maintenance procedure. AquaWIT V Operating Instructions 29748887 AB...
Page 186 Select the minimum water temperature Celsius temperature. The temper- ature is monitored by the TT01 sensor. Sanitisation time Time in seconds Select the time used to flush the flow path with water of the selected temperature. AquaWIT V Operating Instructions 29748887 AB...
Page 187 Action Tip: Suggestions for sanitization parameters are described in the Sanitization of the AquaWIT V integrity test system and its extensions (AquaWIT V MUX and Flush Set) Test Report 20230811LLR01. Note: button to return to the Main menu, the selected parameters are not If you tap the saved.
Page 188 1. The Flowstar V instrument pressurizes the flow path with air to drain water from the flow path through port F to the waste line. 2. The system drains water from the water tank. AquaWIT V Operating Instructions 29748887 AB...
Page 189: Steaming-In-Place (Sip)
Prepare the flow path. a. Install the maintenance manifolds, see Section 8.4.4 Before you start a sanitization run, on page 177. b. Connect port E to the supply line of the steam supply line. AquaWIT V Operating Instructions 29748887 AB...
Page 190 Use the supplied TC-clamps with hexagonal heads to fasten the connections to the system for maintenance procedures. Tighten the TC-clamps with a wrench and verify each connection individually before running the maintenance procedure. Tap Steam Sanitisation. AquaWIT V Operating Instructions 29748887 AB...
Page 191 The temperature is monitored by the TT01 sensor. Note: button to return to the Main menu, the selected parameters are not If you tap the saved. AquaWIT V Operating Instructions 29748887 AB...
Page 192 Target sanitisation temperature + 6°C. Note: The system does not monitor the pressure of the steam supply. The pres- sure must be constant to successfully run a SIP procedure. AquaWIT V Operating Instructions 29748887 AB...
Page 193 Air flush time. 3. If the system does not cool down to the Default system cooling target temperature after the Air flush time, a warning is included in the test result. AquaWIT V Operating Instructions 29748887 AB...
Page 194: Air Flush
Burn hazard. A small amount of steam or condensate can be released from port E during the air flush procedure. The conden- sate trap might contain steam or condensate if the air flush proce- dure is started immediately after steaming. AquaWIT V Operating Instructions 29748887 AB...
Page 195 Parameter Setting Description System air flush Pressure in mbar Select the maximum air pressure pressure to flush the system. System air flush time Time in seconds Select the time for the air flush sequence. AquaWIT V Operating Instructions 29748887 AB...
Page 196 The temperature is monitored by the TT01 sensor. Tip: Suggestions for air flush parameters are described in the Air flush of the AquaWIT V integrity test system and its extensions (AquaWIT V MUX and Flush Set) Test Report 20230811LLR03. Note:...
Page 197 Air flush time. 3. If the system does not cool down to the Default system cooling target temperature after the Air flush time, a warning is included in the test result. AquaWIT V Operating Instructions 29748887 AB...
Page 198: Replacement
This section describes procedures and recommendations for replacing parts and components on the system. In this section Section See page 8.5.1 Safety precautions 8.5.2 Before you replace components 8.5.3 Replacing valve membranes 8.5.4 Replacing Flowstar V AquaWIT V Operating Instructions 29748887 AB...
Page 199: Safety Precautions
Only personnel authorized by Cytiva may perform service and maintenance of the product. WARNING Use only approved parts. Only spare parts and accessories that are approved or supplied by Cytiva can be used for maintaining or servicing the product. AquaWIT V Operating Instructions 29748887 AB...
Page 200 8 Maintenance 8.5 Replacement 8.5.1 Safety precautions WARNING If a fuse requires repeated replacement, do not continue to use the instrument. Contact an authorized service engineer. AquaWIT V Operating Instructions 29748887 AB...
Page 201: Before You Replace Components
Hazardous voltage. The locations marked with the electrical hazard symbol, such as the power box, conduct electricity even when the power switch is switched off. Disconnect the power cable before starting any repair work. AquaWIT V Operating Instructions 29748887 AB...
Page 202: Replacing Valve Membranes
8 Maintenance 8.5 Replacement 8.5.3 Replacing valve membranes 8.5.3 Replacing valve membranes Follow the instructions of the manufacturer to replace the valve membranes. AquaWIT V Operating Instructions 29748887 AB...
Page 203: Replacing Flowstar V
Shut down the system, on page 161. If applicable, disconnect the Flowstar V Printer. Remove the top cover. Unscrew the thumb screw under the table surface. Unplug the connectors on the right side of the Flowstar V instrument. AquaWIT V Operating Instructions 29748887 AB...
Page 204 Carefully lift the Flowstar V instrument from the system. Install the Flowstar V instrument Install the Flowstar V instrument on the system in the reverse order as described in Remove the Flowstar V instrument, on page 203. AquaWIT V Operating Instructions 29748887 AB...
Page 205: Storage
Empty the flow path, as described in Section 8.4.8 Air flush, on page 194. Disconnect from the liquid supply, the electrical power, and the pneumatic supply. a. Shut down the system, see Shut down the system, on page 161. AquaWIT V Operating Instructions 29748887 AB...
Page 206: Long Term Storage
Cleaning-in-place (CIP), on page 180. After long-term storage of more than 6 months, it is recommended that trained and certified personnel perform a preventive maintenance procedure on the following parts: • all components • sensors AquaWIT V Operating Instructions 29748887 AB...
Page 207 The lid on the water tank can be stuck after the system has been closed for a longer period of time. Replacement of the O-ring that seals the tank lid might be necessary. Contact your local Cytiva representative for more information if required. AquaWIT V Operating Instructions 29748887 AB...
Page 208: Biannual Testing Of The Emergency Stop Functionality
Actuate each installed valve to the pressurized state. Press the EMERGENCY STOP button. Result: All valves return to their depressurized state. Try to actuate all valves. Result: The valves are not intended to actuate. AquaWIT V Operating Instructions 29748887 AB...
Page 209 HMI. b. Enter a comment. c. Enter your Login ID and Password. d. Tap OK. Verify that the valves are working properly. Note: If the test fails, contact your local company representative. AquaWIT V Operating Instructions 29748887 AB...
Page 210: Troubleshooting
This chapter provides information to assist users and service personnel to identify and correct prob- lems if they occur. If the suggested actions in this guide do not solve the problem, or if the problem is not covered by this guide, contact your Cytiva representative for advice. In this chapter Section...
Page 211: Self Test
SELF TEST FAILED Contact service. • An internal pressure sensor deviates from the set threshold. • A leakage occurred in the flow path. • A valve malfunctions. AquaWIT V Operating Instructions 29748887 AB...
Page 212: Filter Integrity Test (Ff/Wit/Lt/Fc)
Verify that the flow path is filter housing. free of leaks. • • The filter is non-integral. Replace the filter, if needed. • • The filter membrane is not Re-wet (FF test) and re-test wetted completely. the filter. AquaWIT V Operating Instructions 29748887 AB...
Page 213 There are fluctuations in the compressed air supply, the compressed air supply. if needed. LINE PRESSURE UNSTABLE The pressure of the Verify the pressure of the compressed air supply is not compressed air supply. stable enough. AquaWIT V Operating Instructions 29748887 AB...
Page 214 There are fluctuations in the compressed air supply. SETUP ERROR The pressurization of the filter • Verify that the filter is did not start. connected. • Verify that the external vent valve opens and closes correctly. AquaWIT V Operating Instructions 29748887 AB...
Page 215: Bubble Point Test
• The wrong external sensor • type is selected in Verify that the correct type AquaWIT Configuration. of external sensor is selected in the software, Section 5.3.8 Connect external sensors, on page AquaWIT V Operating Instructions 29748887 AB...
Page 216 • Re-test the filter in a system that has a higher pressure tolerance. • Replace the filter, if needed. AquaWIT V Operating Instructions 29748887 AB...
Page 217 Verify that the filter is did not start. connected. • Verify that the external vent valve opens and closes correctly. • Contact service if the external vent valve is defect. If needed, replace the external vent valve. AquaWIT V Operating Instructions 29748887 AB...
Page 218: Pressure Decay Test
There are fluctuations in the compressed air supply. SETUP ERROR The pressurization of the filter • Verify that the filter is did not start. connected. • Verify that the external vent valve opens and closes correctly. AquaWIT V Operating Instructions 29748887 AB...
Page 219: System
INSUFFICIENT The temperature does not Verify that the steam inlet or TEMPERATURE reach the sanitization temper- the hot water supply inlet is ature during the system filling connected and working. phase. AquaWIT V Operating Instructions 29748887 AB...
Page 220 Verify that the filter housing inlet is open. PT01 DEFECT The pressure sensor PT01 • Go to Tools →AquaWIT measurement is misaligned Manual Operation and verify that the pressure is displayed. • Replace the pressure sensor. AquaWIT V Operating Instructions 29748887 AB...
Page 221 CAN bus cable but cable from the extension. instrument is not the Active Extension is set to • Set the Active Extension connected to the AquaWIT AquaWIT V. to the relevant extension. Base Unit. AquaWIT V Operating Instructions 29748887 AB...
Page 222 The level switch LSL04 does • Verify that the System not indicate Empty status drain time setting is after the timeout of a tank correct. drain phase. • Verify that drain port F is not blocked. AquaWIT V Operating Instructions 29748887 AB...
Page 223 Warning: Filter drain did Water remains in the filter • Verify that drain port F is not complete housing or in the piping up to not blocked. LSH05. • Verify that the filter is connected. AquaWIT V Operating Instructions 29748887 AB...
Page 224 The temperature drops for a Verify that the steam inlet or temperature drop short time below the sanitiza- the hot water supply inlet is detected tion temperature during a connected and working. sanitization loop. AquaWIT V Operating Instructions 29748887 AB...
Page 225: Reference Information
10 Reference information 10 Reference information About this chapter This chapter lists technical specifications of the AquaWIT V system. The chapter also includes a chemical resistance guide, recycling information, and regulatory information. In this chapter Section See page 10.1 Specifications 10.2...
Page 226: Specifications
Adjust the PPE use according to the actual acoustic noise level. Control system HMI on the Flowstar V instrument Refer to the Technical Specification of the Filter type system AquaWIT V Operating Instructions 29748887 AB...
Page 227: Environmental Requirements
18°C to 24°C (64 to 77°F) Operating temperature range, hot water < 90°C (< 194°F) Operating temperature range, saturated < 131°C (< 267.8°F) steam Liquids under flammable conditions Not allowed Operation in potentially explosive environment Not allowed AquaWIT V Operating Instructions 29748887 AB...
Page 228: Ingress Protection
Instrument air pressure limits 5 to 8 bar (72.5 to 116 psi) Instrument air and process air Oil and particle free, non-condensing air or nitrogen gas quality (according to ISO 8573-1:2010 Class 3.4.4 or better) AquaWIT V Operating Instructions 29748887 AB...
Page 229: Chemical Resistance
10 Reference information 10.2 Chemical resistance 10.2 Chemical resistance Introduction This section gives general guidelines concerning chemical resistance for AquaWIT V components. Regarding exposure to solutions not covered by these guidelines, contact your Cytiva representative for recommendations. Flow path All chemicals and concentrations are for short-term (< 1 day) use only, if not otherwise stated. Long- term use is defined as up to one month.
Page 230: Recycling Information
When taking the product out of service, the different materials must be separated and recycled according to national and local environmental regulations. Recycling of hazardous substances The product contains hazardous substances. Detailed information is available from your Cytiva representative. Disposal of electrical components Waste electrical and electronic equipment must not be disposed of as unsorted municipal waste and must be collected separately.
Page 231: Instructions For Disposal
Follow local and/or national/federal requirements for disposal of the electronic components. Tip: To return the system to Cytiva for recycling, refer to the sustainability page from regulatory support on cytiva.com. AquaWIT V Operating Instructions 29748887 AB...
Page 232: Regulatory Information
Flowstar V Integrity Test Instrument Operating Instructions. In this section Section See page 10.4.1 Contact information 10.4.2 European Union and European Economic Area 10.4.3 Great Britain 10.4.4 North America 10.4.5 South Korea 10.4.6 General regulatory statements AquaWIT V Operating Instructions 29748887 AB...
Page 233: Contact Information
To find local contact information for support and sending troubleshooting reports, visit cytiva.com/ contact. Manufacturing information The table below summarizes the required manufacturing information. Requirement Information Name and address of manufacturer Cytiva Germany GmbH Philipp-Reis-Str. 6 63303 Dreieich Germany AquaWIT V Operating Instructions 29748887 AB...
Page 234: European Union And European Economic Area
The CE marking and the corresponding EU Declaration of Conformity is valid for the product when it • used according to the Operating Instructions or user manuals, and • used in the same state as it was delivered, except for alterations described in the Operating Instructions or user manuals. AquaWIT V Operating Instructions 29748887 AB...
Page 235: Great Britain
• used according to the Operating Instructions or user manuals, and • used in the same state as it was delivered, except for alterations described in the Operating Instructions or user manuals. AquaWIT V Operating Instructions 29748887 AB...
Page 236: North America
Note: The user is cautioned that any changes or modifications not expressly approved by Cytiva could void the user’s authority to operate the equipment. This equipment has been tested and found to comply with the limits for a Class A digital device, pursuant to part 15 of the FCC Rules.
Page 237: South Korea
When used in a residential environment, there is a concern of radio interference. 유의사항 A급 기기 (업무용 방송통신 기자재) 이 기기는 업무용환경에서 사용할 목적으로 적합성평가를 받 은 기기 로서 가정용 환경에서 사용하는 경우 전파간섭의 우려가 있습 니다. AquaWIT V Operating Instructions 29748887 AB...
Page 238: General Regulatory Statements
This section describes the information that is applicable to more than one geographical region. EMC emission, CISPR 11: Group 1, Class A statement NOTICE This equipment is not intended for use in residential environments and may not provide adequate protection to radio reception in such environments. AquaWIT V Operating Instructions 29748887 AB...
Page 239: Index
Delivery, 71, Flush extension, box storage, description, box transportation, Front, Description, 29–31 illustration, BP method, FF + BP method, FF method, maintenance procedures, General precautions, WIT method, Grounding, Dimensions, Disposal, instructions, HMI, Documentation package, overview, AquaWIT V Operating Instructions 29748887 AB...
Page 240 Notes and tips, frequency, Shut down, SIP, SIP conditions, Operator, Site requirements, power supply, Software settings, 53, 59, 61, 63–66 AquaWIT V, Personal protection, precautions, cleaning, Power box, external sensor, disposal, Power requirements, filter, AquaWIT V Operating Instructions 29748887 AB...
Page 241 Typographical conventions, conformity, UKCA, marking, Valves, external, overview, Water tank, 33, 41, 42, 59, 171, cleaning, illustration, overview, 41, reassemble, software settings, WIT, software settings, AquaWIT V Operating Instructions 29748887 AB...
Page 242 QR code. cytiva.com Cytiva and the Drop logo are trademarks of Life Sciences IP Holdings Corporation or an affiliate doing business as Cytiva. Any other third-party trademarks are the property of their respective owners. © 2025 Cytiva For local office contact information, visit cytiva.com/contact...

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