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Related Manuals for REPLIGEN TangenX SIUS
Summary of Contents for REPLIGEN TangenX SIUS
- Page 1 TangenX® SIUS® Auto-Torque Holders and System User Guide UG-3218 R1...
- Page 2 Customer shall refer to the terms and conditions of sale governing the transaction for any and all warranties for the Product. Repligen Corporation shall not be liable for errors contained herein or for incidental or consequential damages in connection with the furnishing, performance, or use of this material.
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Page 3: Table Of Contents
User Guide TangenX® SIUS® Auto-Torque Holders and System User Guide KrosFlo® TFDF™ Lab System Contents Introduction ..........................5 Safety Conventions in this manual ....................6 Before you begin ........................6 Holder Mounting and Installation ....................9 3.1 Tools required ........................9 3.2 TangenX® SIUS® Filter Plate installation ................10 3.3 TangenX®... - Page 4 User Guide TangenX® SIUS® Auto-Torque Holders and System User Guide KrosFlo® TFDF™ Lab System List of tables Table 1. TangenX® SIUS® Vertical Cassette Holder specifications ............5 Table 2. TangenX® Filter Plate Insert (FPI) specifications ...............5 Table 3. TangenX® SIUS® Vertical Cassette Clamp components list ............8 Table 4.
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Page 5: Introduction
TFP99-SP20 (Bi-directional) Holder compatibility V1AC, V2AC, V3AC Cassette compatibility G05L, G05E, G05J, G15L, G15E, G15J, G25L, G25E, G25J Material of construction Polypropylene (Class VI BSE Free) Connections 1” tri-clamp 1.5” tri-clamp Maximum flow rate 49 LPM 140 LPM repligen.com UG-3218 R1... -
Page 6: Safety Conventions In This Manual
2. TangenX® SIUS® Vertical Cassette Holders weigh approximately 100 - 150 lb (45 – 70 kg) depending on the size. System components are very heavy. Take proper precaution when WARNING: lifting or moving the equipment or components to prevent personal injury. In some cases, hoists or other lifting equipment may be required. repligen.com UG-3218 R1... - Page 7 Gasket for TangenX® SIUS® Cassettes 1. Gaskets are intended to be single use; Repligen recommends that you replace gaskets with each cassette changeover. 2. Repligen supplies two gaskets per cassette. Installation of the first cassette requires two gaskets –...
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Page 8: Table 3. Tangenx® Sius® Vertical Cassette Clamp Components List
Cassette SIUS Cassette Up to 30 m 10. Filter Plate Insert TFP99-SP20 Table 1 for total area Auto-Torque = TangenX® SIUS® Auto-Torque components Holder = TangenX® SIUS® Vertical 2-bolt Holder components (for V1AC, V2AC V3AC holders) repligen.com UG-3218 R1... -
Page 9: Holder Mounting And Installation
6. Connect the hydraulic pump to a compressed air connection with at least 75 psi air pressure. The pump maximum capacity is 100 psi to achieve full clamping capacity of the pump. Refer to TangenX® Hydraulic System EH10236 section for pump operation instructions. Figure 4. Foot Plate Figure 5: Mounting Hole Locations repligen.com UG-3218 R1... -
Page 10: Tangenx® Sius® Filter Plate Installation
Long fitting/tubing runs consisting of tees with valves and gauges may create sufficient force to cause the plastic filter plate connection to crack and/or break off. repligen.com UG-3218 R1... -
Page 11: Tangenx® Sius® Cassette Installation
Be careful when loosening the holder clamping plates as WARNING: they are heavy and create a possible pinch point. Never place your hands between the clamping plates when the hydraulic pump is running. 9. Load the washers and hex nuts (2 each). repligen.com UG-3218 R1... -
Page 12: Tangenx® Sius® Cassette Equilibration
5. TangenX® SIUS® Cassette and system cleaning TangenX® SIUS® Cassettes are intended for single-use, therefore post-use cleaning and re-use is not recommended nor supported by Repligen. Similarly, the Filter Plate Insert is also designed for single- use and post-use cleaning is not supported by Repligen. -
Page 13: Disposing Of Used Tangenx® Sius® Cassettes
Table 5. Pump pressure Maximum pump air inlet pressure 100 psi (6.9 bar) Maximum pump hydraulic pressure 3,600 psi (248 bar) Hydraulic relief valve set-point (by Repligen) 1,500 psi (103 bar) Maximum cylinder capacity 10 cylinders 9.2 Installation Pump filling - THE PUMP IS SHIPPED WITHOUT HYDRAULIC FLUID IN THE RESERVOIR. -
Page 14: Operation
Figure 9. Pump envelope dimensions 9.3 Operation 1. To operate the pump, close the tank control valve, and turn the air pressure regulator counterclockwise for minimum air pressure (10). 2. Turn the control switch to the “ON” position (Figure 10). repligen.com UG-3218 R1... -
Page 15: Figure 10. Control Switch
Caution: Do not exceed 1500 psi when operating with TangenX® cassettes. Note: To quickly decrease hydraulic pressure, the tank control valve Figure 8 must be opened to relieve any excess hydraulic pressure after the air regulator is adjusted. repligen.com UG-3218 R1... -
Page 16: Table 6. Hydraulic Pressure Specifications For Tangenx® Tff Cassettes
B. Hydraulic pressure gauge C. Air exhaust D. Hydraulic hose to filter holder E. Air pressure gauge F. Air supply inlet G. Hydraulic relief valve H. Remove (4) screws and cover to change or add hydraulic fluid repligen.com UG-3218 R1... -
Page 17: Operation Precautions
The air pressure regulator may need to be adjusted to reach the corresponding Hydraulic pressure measured by the Hydraulic pressure gauge. Figure 13: Adjustment for Non TangenX® Cassettes A. Hydraulic relief Valve B. Air pressure Regulator C. Air pressure gauge D. Hydraulic pressure gauge repligen.com UG-3218 R1... -
Page 18: Appendix
User Guide TangenX® SIUS® Auto-Torque Holders and System 9.6 Appendix Figure 13. OEM Manufacturer Certificate of Compliance example repligen.com UG-3218 R1... -
Page 19: Figure 14. Oem Manufacturer Inspection And Test Report Example
User Guide TangenX® SIUS® Auto-Torque Holders and System Figure 14. OEM Manufacturer Inspection and Test Report example repligen.com UG-3218 R1... - Page 20 User Guide TangenX® SIUS® Auto-Torque Holders and System repligen.com UG-3218 R1...
- Page 21 User Guide TangenX® SIUS® Auto-Torque Holders and System repligen.com UG-3218 R1...
- Page 22 User Guide TangenX® SIUS® Auto-Torque Holders and System repligen.com UG-3218 R1...
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Page 23: Figure 15. Oem Manufacturer Pump Safety Instructions Example
User Guide TangenX® SIUS® Auto-Torque Holders and System Figure 15. OEM Manufacturer Pump Safety Instructions example repligen.com UG-3218 R1... -
Page 24: Index
10. Index Caution ............6, 15 Installation ........10, 11, 12, 13 Certificate ............18 OEM ..........13, 18, 19, 23 Cleaning ..........12, 15 Operation ..........9, 15 Components ........8, 12, 13 Precaution .............17 Hydraulic fluid ........13, 16, 17 Specifications ..........5, 16 repligen.com UG-3218 R1...
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