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REPLIGEN Manuals
Laboratory Equipment
XCell ATF Series
User manual
REPLIGEN XCell ATF Series User Manual
With c410:v4b controller
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Contents
Table of Contents
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Table of Contents
Table of Contents
1 Description of the Xcell™ ATF (Alternating Tangential Flow) System and Process
Xcell TM ATF System Pump Cycle
Xcell™ ATF System Control Scope and Objectives
2 Utility Requirements
3 Dimensions and Weight
4 Xcell™ ATF Pump Housing Assemblies
See Appendix 7 for List of Spares and Accessories
5 Xcell TM C410V4B Controller Layout
General Layout
Filtration Assembly (Stainless Steel)
Pneumatics Box (P-Box) Components
Electrical Box (E-Box)
Power Box (Power Separation) Components
Primary Pneumatic Services
Primary Electric Services
Signal
6 C410V4B Controller Process and Control
Control Overview
Control Functional Algorithms
Interface and Screens
Startup
Examples
7 Xcell™ ATF Hollow Fiber Module and Diaphragm Replacement
Separating the Filtration Assembly from the Bioreactor
HFM Removal
HFM Insertion
Screen Module Replacement
Diaphragm Replacement
Assembly
Use
8 Sterilization
Preparation of Filtration Assembly for Autoclaving
Autoclave Cycle
Sterilization of Filtrate / Harvest Line
9 Connection to Bioreactor (ATF-To-Bioreactor)
Hard Connection
10 Maintenance
Diaphragm
Pump Air Inlet Filter
O" Rings, Gaskets and Quick Connects
Appendix 1: Cycle Time Vs. Flow Rate
Appendix 2: Access Levels to the C410V4B Controller
Appendix 3: Controller Lists: Alarm, Warning, Inputs & Outputs
Appendix 4: Profinet Communication
Appendix 5: Profibus Communication
Appendix 6: Delta V Example Configuration
Appendix 7: OPC Communication
Appendix 8: Audit Trail (if Equipped)
Appendix 9: EU Declaration of Conformity
Appendix 10: UL Listing
Appendix 11: Spares List
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Description of the Xcell™ Atf (Alternating Tangential Flow) System and Process
2
Utility Requirements
3
Dimensions and Weight
Download this manual
TM
XCell
ATF System
With C410:V4B Controller
USER GUIDE
XCell ™ ATF4 | XCell ™ ATF6 | XCell ™ ATF10
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This manual is also suitable for:
Xcell atf6
Xcell atf10
Xcell atf4
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