Thermo Scientific NICOLET FT-IR User Manual page 24

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• A weight loss of about 10 mg usually gives an adequate signal.
For example, if a sample loses 50% of its weight during the run,
a 20 mg sample size will probably be adequate. Do not use
excessively large sample sizes. Large weight losses (in terms of
mass) can be accompanied by using aerosols that cause IR
baseline shifts.
20
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