Multimode Source And Hplc-Chip/Ms Interface; To Clean The Multimode Source Daily - Agilent Technologies 6500 Series Maintenance Manual

2 Maintenance

Multimode Source and HPLC-Chip/MS Interface

Multimode Source and HPLC-Chip/MS Interface

This section describes how to clean and adjust the multimode source and
maintain the HPLC-Chip/MS interface.

To clean the multimode source daily

When required
Daily or anytime you suspect carryover contamination from one sample or
analysis to another, or when you must access the end cap and capillary cap for
cleaning and inspection.
Tools required
• Gloves
• Wash bottle, clean
Parts required
• Abrasive paper, 4000 grit (p/n 8660-0827)
• Cloths, clean, lint-free (p/n 05980-60051)
• Cotton swabs (p/n 5080-5400)
• Mobile phase from the current method or clean isopropanol, reagent grade
• Water, reagent-grade or better
1 Turn off the spray chamber, nebulizer pressure, drying gas flow, drying gas
Do not touch the multimode source or the capillary cap. They may be very hot. Allow
WA R N I N G
the multimode source to cool down before you handle them.
2 Remove the nebulizer and the APCI corona needle.
3 Remove the cosmetic cover. You will have to remove the thermocouple
4 Open the spray chamber.
102
or better
temp, and vaporizer temp.
probe before you can wipe the spray chamber. Otherwise, leave the
thermocouple intact.
Agilent 6500 Series Q-TOF LC/MS Maintenance Guide