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Summary of Contents for Sartorius CIMmultus SDVB
- Page 1 Instructions for Use CIMmultus™ SDVB 80 mL Monolithic Column (2 µm channels) ® CIM Convective Interaction Media 611.9001-2...
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Page 2: Table Of Contents
Contents Contents About These Instructions for Use................................3 1.1. Accompanying Documents..................................3 Safety..........................................3 2.1. Intended Use........................................3 2.2. Safety Note........................................3 Technical Data....................................... 3 Device Overview | Description ................................4 Installation........................................5 Getting Started......................................5 6.1. General Recommendations..................................5 6.2. Buffer Selection......................................6 Operating the Column.................................... -
Page 3: About These Instructions For Use
About These Instructions for Use 1. About These Instructions for Use These instructions are part of the device. They apply to the device product number indicated on the cover page. 1.1. Accompanying Documents Column integrity test 2. Safety ... -
Page 4: Technical Data
Device Overview | Description 3. Technical Data Column chemistry SDVB (reverse phase; poly(styrene-co-divinylbenzene)) Channel radius 1050 nm (950 nm – 1150 nm) Support matrix poly(styrene-co-divinylbenzene) Monolith dimensions Outer diameter: 34 mm; inner diameter: 15 mm; length: 110 mm; bed volume (CV): 80 Connector TC 1 in. -
Page 5: Installation
Installation 5. Installation Remove the product from its shipping box or crate and place on a flat surface. Carefully inspect the product for any damage that may have occurred during shipping. Immediately report any such damage to your vendor and the courier. -
Page 6: Buffer Selection
Getting Started NOTICE Always ensure mobile phases are compatible before mixing them or applying consecutively on the column. Examples of in-compatible buffers are: magnesium ion-containing buffers and sodium hydroxide (forms precipitate), acetonitrile and sodium hydroxide (forms ammonia and acetate), ammonium acetate and sodium hydroxide (potential formation of explosive atmosphere), ethanol and sodium hydroxide (forms ethoxides). -
Page 7: Equilibration
Operating the Column Connecting the column to the system is possible with an inlet placed either at the top or at the bottom. Connect the column to the system with flow turned off in the following order: 1. Carefully remove the blind fitting on the inlet side and connect the inlet tubing. 2. -
Page 8: Sanitisation
Cleaning | Maintenance Sample molecules may bind to the column strongly and not completely elute from the column or may even precipitate on the column. This build-up of contaminants on the monolithic column may cause loss of resolution and binding capacity, increased back pressure, or a complete blockage of the column. A specific CIP procedure should be considered for the type of contaminants present in the sample. -
Page 9: Troubleshooting
(biaseparations.com/en/library/guidelines). 11. Decommissioning | Transportation If there is reason to return the product, complete a Return Form (biaseparations.com/en/terms-conditions) and contact help.bia@sartorius.com. Contaminated samples used during the process that could cause biological or chemical hazards are potentially hazardous substances. If the product has come into contact with hazardous substances, steps must be taken to ensure proper decontamination and declaration. -
Page 10: Ordering Information
Ordering Information 12. Ordering Information Transferring the workflow to a different scale or format (analytical, screening) is simple with CIM™. Contact your local support to find the appropriate products. Purification Scale Products cGMP Compliant Catalog number Product name 901.9001-2 CIMmultus™ SDVB 8 mL cGMP Compliant Monolithic Column (2 µm channels) 914.9001-2 CIMmultus™... - Page 11 Ordering Information Instructions for Use 611.9001-2...
- Page 12 The information and figures contained in these instructions correspond to the version date specified below. Sartorius reserves the right to make changes to the technology, features, specifications and design of the equipment without notice. Masculine or feminine forms are used to...
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