Related Manuals for cytiva F9-R
Summary of Contents for cytiva F9-R
- Page 1 Fraction collector F9-R Operating Instructions Original instructions F9-R cytiva.com...
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Page 2: Table Of Contents
Евразийский экономический союз ....................53 7.4.4 Regulations for North America ....................... 55 7.4.5 Regulatory statements ..........................56 7.4.6 Declaration of Hazardous Substances (DoHS) ................57 Health and Safety Declaration Form ...................... 59 Index ........................... 61 Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 3: Introduction
This chapter contains information about this manual and associated user documenta- tion, important user information and intended use of the product. In this chapter Section See page Important user information About this manual Associated documentation Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 4: Important User Information
Intended use Fraction collector F9-R is an automated fraction collector intended for the collection of fractions from purification runs. It is intended for research use only, and shall not be used in clinical procedures, or for diagnostic purposes. -
Page 5: About This Manual
The Operating Instructions manual provides information needed to install, operate and maintain the product in a safe way. Scope of this manual The Operating Instructions manual covers Fraction collector F9-R, in the manual also referred to as the product. Typographical conventions Software items are identified in the text by bold italic text. -
Page 6: Associated Documentation
User documentation for compatible purification systems This section lists examples of user documentation for purification systems that can be used together with this product. The manuals can be downloaded from cytiva.com. Documentation Main contents Operating Instructions for the ÄKTA™... - Page 7 It is then possible to navigate further to find, for example, software manuals. Tip: There are specific help texts for instructions that only can be reached by marking the instruction and pressing F1. Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 8: Safety Instructions
Labels and symbols Emergency procedures Important WARNING Before installing, operating or maintaining the product, all users must read and understand the entire contents of this chapter to become aware of the hazards involved. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 9: Safety Precautions
NOTICE indicates instructions that must be followed to avoid damage to the product or other equipment. General precautions WARNING Do not operate Fraction collector F9-R in any other way than described in the Operating Instructions. WARNING Operation and user maintenance of Fraction collector F9-R should be performed by properly trained personnel only. - Page 10 Accessories. Use only accessories supplied or recommended by Cytiva. WARNING Do not use Fraction collector F9-R if it is not working properly, or if it has suffered any damage, for example: • damage to the power cord or its plug •...
- Page 11 Avoid spillage and overflow. Make sure that the equipment is prepared according to the settings in the method to be run. CAUTION Replacement of the fraction collector bowl in Fraction collector F9-R. Do not replace the bowl during a run. Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 12 Maintenance CAUTION Electrical shock hazard. All repairs should be done by service personnel authorized by Cytiva. Do not open any covers or replace parts unless specifically stated in the user documentation. CAUTION Disconnect power. Always switch off power to Fraction collector F9-R, before cleaning any of its components, unless stated other- wise in the user documentation.
- Page 13 2.1 Safety precautions CAUTION Cleaning Fraction collector F9-R before decommissioning. • Wipe Fraction collector F9-R with a damp tissue using a cleaning agent so that no hazardous solvents or biological agents remain on the surface. • Perform a system CIP using a neutral solution. Make sure that any hazardous solvents or biological agents are flushed out from the fraction collector.
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Page 14: Labels And Symbols
Please contact an authorized representative of the manufacturer for information concerning the decommissioning of equipment. The fraction collector complies with applicable Euro- pean directives Fraction collector F9-R Operating Instructions 29656880 AA... - Page 15 2 Safety instructions 2.2 Labels and symbols Label text Meaning The equipment complies with the applicable require- ments for Australia and New Zealand Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 16: Emergency Procedures
Introduction The ÄKTA instrument supplies the Fraction collector F9-R with power. This section describes how to perform an emergency shutdown of the Fraction collector F9-R by shutting down the ÄKTA instrument. This section also describes the result in the event of power failure or network interrup- tion. - Page 17 The sample and data may be lost as a result of switching off the power. Power failure In case of a power failure or if communication is lost, the run is interrupted immediately and all moving parts in the fraction collector are stopped. Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 18: Overview
3 Overview Overview About this chapter This chapter gives an overview of Fraction collector F9-R and suitable disposables and accessories to be used with the fraction collector. In this chapter Section See page Function Illustrations Tubes Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 19: Function
• Peak fractionation • Combined fixed volume fractionation and peak fractionation • Collecting fractions in reversed phase separations using organic solvents Fraction collector F9-R has the following function for reducing sample spill during frac- tionation: • Drop Sync Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 20: Illustrations
3 Overview 3.2 Illustrations Illustrations Introduction This subsection provides illustrations of Fraction collector F9-R. The main features and components are indicated. Fraction collector F9-R Operating Instructions 29656880 AA... - Page 21 Front view The illustration below shows the main parts of the Fraction collector. Part Function Lock knob Stationary part of delivery arm Delivery arm Tubing connector Tube sensor Collection tubes Tube rack Base unit Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 22 3 Overview 3.2 Illustrations Connector panel The illustration below shows the main parts of the connector panel on the fraction collector. Part Function Node ID switch UniNet-9 F-type connector (for communication and power supply) Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 23: Tubes
Tubes Introduction For Fraction collector F9-R the fractions are collected in tubes of different sizes. For more information on requirements that need to be fulfilled by the tubes to be used in Fraction collector F9-R, see the ÄKTA go User Manual (29391392), the ÄKTA pure User Manual (29119969) or the ÄKTA avant User Manual (29035184). - Page 24 Tube guide Tube holder Note: Note that the tube guide has both single and L-shaped cutouts, while the tube holder only has single cutouts. See Assemble the Tube rack, on page for more information. Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 25: Installation
This chapter provides required information on how to prepare for, and perform an installation of Fraction collector F9-R. In this chapter Section See page Site preparation Connections to the ÄKTA instrument Delay volume Performance test Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 26: Site Preparation
The peformance specifications of the fraction collector can be met only if the labora- tory environment fulfills the requirements stated in this section. In this section Section See page 4.1.1 Delivery and storage 4.1.2 Space requirements 4.1.3 Site requirements Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 27: Delivery And Storage
When you receive the delivery • Record on the receiving documents if there is any apparent damage on the delivery box. Inform your Cytiva representative of such damage. • Move the delivery box to a protected location indoors. Storage requirements The delivery box should be stored in a protected place indoors. -
Page 28: Space Requirements
4.1.2 Space requirements 4.1.2 Space requirements Introduction This section describes the different options of placement of Fraction collector F9-R and the space required. Location Place the fraction collector on a clean, flat and stable area that is able to support the weight of the fraction collector. - Page 29 Size and weight The size and weight of the fraction collector are stated in the table below. Parameter Value W (width) 320 mm H (height) 250 mm D (depth) 400 mm Weight 5 kg Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 30: Site Requirements
This section describes the site requirements for installation of the fraction collector. Environmental requirements If flammable liquids are fractionated, make sure that the ventilation meets the local requirements. For other environmental requirements, refer to the Operating Instructions for the ÄKTA instrument. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 31: Connections To The Äkta Instrument
• it must be a Fraction collector F9-R, • it has to be configured as Fraction collector F9-R, 2nd, • the node ID has to be changed, as described in the Fraction collector F9-R Operating Instructions (29656880). In this section... -
Page 32: Power And Communication
This subsection describes how to set up the power and communication connection between Fraction collector F9-R and the ÄKTA pure instrument. Connect fraction collector The Fraction collector F9-R is connected to the Fraction collector F9-R instrument using a UniNet-9 cable, F-type. WARNING UniNet cable. - Page 33 In the Administration module, choose Tools →System Properties or click the System Properties icon to open the dialog. Result: The System Properties dialog is displayed. Select a system in the System Properties dialog. Note: Only active systems can be edited. Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 34 Instrument modules are referred to as Components in UNICORN. Note: An outlet valve has to be selected in order to select a fraction collector. Result: All available fraction collectors are shown in the Component selection list. Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 35 • the fraction collector is to be used as a primary fraction collector after it has been used as secondary. The Node ID for Fraction collector F9-R is set by positioning the arrow of the rotating switch at the back of the fraction collector. Use a screwdriver to set the arrow of the switch to the desired number.
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Page 36: Tubing Connections
Re-install the tubing connector on the delivery arm. Connect the tubing from the fraction collector to the outlet valve. • If using one Fraction collector F9-R, connect the tubing from the fraction collector to the Frac port on the outlet valve. - Page 37 4 Installation 4.2 Connections to the ÄKTA instrument 4.2.2 Tubing connections Step Action • If using a second Fraction collector F9-R, connect the tubing from the second fraction collector to the outlet valve as indicated below. Outlet valve Port V9-O...
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Page 38: Delay Volume
(e.g., the value for Monitor to outlet valve is ignored if you are using a fraction collector). It is however recommended to set all delay volumes so that the volumes remain correct if you change frac- tionation method. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 39: Performance Test
4 Installation 4.4 Performance test Performance test Before taking the Fraction collector F9-R instrument into use, run a performance test to check the function of the equipment. See the User Manual of the purification instru- ment for further instructions. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 40: Operation
This chapter describes how to prepare and assemble the fraction collector before a run. The Fraction collector F9-R is connected to ÄKTA go, ÄKTA pure or ÄKTA avant and controlled by UNICORN. Control of the fraction collector can be achieved automatically in a method run, or manually. - Page 41 • Check that tube position 1 (7) is directly above tube position 1 (7) of the Tube guide. • Push the flexible bowl out at each rib and snap the Tube holder under the top lip of the rib (8). Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 42 Gently move the Delivery arm (10) out to the outer stop. Place the Tube rack (9) over the Central spindle (11) and pull the spring loaded Drive sleeve (12) out so the Tube rack comes to rest. Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 43 Gently lift and then lower the delivery arm, and allow it to move in so the tube sensor touches the collection tubes of the outer track. Adjust the height of the delivery arm as follows: a. Loosen the lock knob Fraction collector F9-R Operating Instructions 29656880 AA...
- Page 44 Check that the tube sensor is in the correct position for the used tubes. The eluent tubing should be above the center of the collection tube. Use the sensor control to position the tube holder. Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 45: Maintenance
Switch off the instrument. Wipe the surface with a damp cloth. Wipe off stains using a mild cleaning agent or 20% ethanol. Wipe off any excess. Let the Fraction collector F9-R dry completely before restart. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 46: Reference Information
Health and Safety Declaration form for service. In this chapter Section See page Specifications Chemical resistance Recycling information Regulatory information Health and Safety Declaration Form Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 47: Specifications
Relative humidity 20% to 95%, non-condensing Altitude, operating Up to 2000 m Pollution degree of the intended envi- Pollution degree 2 ronment Chemical environment Refer to the User Manual for the ÄKTA instrument. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 48: Chemical Resistance
7 Reference information 7.2 Chemical resistance Chemical resistance Refer to the Operating Instructions for the ÄKTA instrument for chemical resistance specifications. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 49: Recycling Information
Waste electrical and electronic equipment must not be disposed of as unsorted munic- ipal waste and must be collected separately. Please contact an authorized representa- tive of the manufacturer for information concerning the decommissioning of the equipment. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 50: Regulatory Information
See page 7.4.1 Contact information 7.4.2 European Union and European Economic Area 7.4.3 Eurasian Economic Union Евразийский экономический союз 7.4.4 Regulations for North America 7.4.5 Regulatory statements 7.4.6 Declaration of Hazardous Substances (DoHS) Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 51: Contact Information
The table below summarizes the required manufacturing information. Requirement Information Name and address of manufacturer Cytiva Sweden AB Björkgatan 30 SE 751 84 Uppsala Sweden Telephone number of manufacturer + 46 771 400 600 Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 52: European Union And European Economic Area
• used according to the Operating Instructions or user manuals, and • used in the same state as it was delivered, except for alterations described in the Operating Instructions or user manuals. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 53: Eurasian Economic Union
Telephone: +7 499 609 15 50 E-mail: rucis@cytiva.com Информация о производителе и импортере В следующей таблице приводится сводная информация о производителе и импортере, согласно требованиям Технических регламентов Таможенного союза и (или) Евразийского экономического союза. Fraction collector F9-R Operating Instructions 29656880 AA... - Page 54 Member States of the Customs Union of the Eurasian Economic Union Данный знак о Евразийском соответствии указывает, что изделие одобрено для использования на рынках государств-членов Таможенного союза Евразийского экономического союза Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 55: Regulations For North America
Note: The user is cautioned that any changes or modifications not expressly approved by Cytiva could void the user’s authority to operate the equip- ment. CAN ICES/NMB compliance This product complies with the Canadian standard ICES-001/NMB-001 concerning electromagnetic compatibility. -
Page 56: Regulatory Statements
When used in a residential environment, there is a concern of radio interference. 유의사항 A급 기기 (업무용 방송통신 기자재) 이 기기는 업무용환경에서 사용할 목적으로 적합성평가를 받 은 기기 로서 가정용 환경에서 사용하는 경우 전파간섭의 우려가 있습 니다. Fraction collector F9-R Operating Instructions 29656880 AA... -
Page 57: Declaration Of Hazardous Substances (Dohs)
Periodic replacement of those consumables or parts to maintain the declared EFUP shall be done in accordance with the Product Maintenance Procedures. This product must not be disposed of as unsorted municipal waste, and must be collected sepa- rately and handled properly after decommissioning. Fraction collector F9-R Operating Instructions 29656880 AA... - Page 58 Indicates that this hazardous substance contained in at least one of the homogeneous materials used for this part is above the limit requirement in GB/T 26572 • Data listed in the table represents best information available at the time of publication. Fraction collector F9-R Operating Instructions 29656880 AA...
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Page 59: Health And Safety Declaration Form
Service Ticket #: To make the mutual protection and safety of Cytiva service personnel and our customers, all equipment and work areas must be clean and free of any hazardous contaminants before a Service Engineer starts a repair. To avoid delays in the servicing of your equipment, complete this checklist and present it to the Service Engineer upon arrival. - Page 60 To make sure the mutual protection and safety of Cytiva personnel, our customers, transportation personnel and our environment, all equipment must be clean and free of any hazardous contaminants before shipping to Cytiva. To avoid delays in the processing of your equipment, complete this checklist and include it with your return.
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Page 61: Index
Fractionation, 24 assemble tube rack, 24 Tube rack, 24 assembly, 24 Typographical conventions, 5 Important user information, 4 Installation, 39 performance test, 39 Instrument overview, 21 Fraction collector F9-R, 21 Manufacturing information, 51 Fraction collector F9-R Operating Instructions 29656880 AA... - Page 62 Standard Software End-User License Agreement is available on request. All goods and services are sold subject to the terms and conditions of sale of the supplying company operating within the Cytiva business. A copy of those terms and conditions is available on request. Contact your local Cytiva representative for the most current information.
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