Christ Epsilon 2-6D LSCplus Operating Manual
  1. Manuals
  2. Brands
  3. Christ Manuals
  4. Laboratory Equipment
  5. Epsilon 2-6D LSCplus
  6. Operating manual

Christ Epsilon 2-6D LSCplus Operating Manual

Freeze-dryer
Hide thumbs
Table of Contents

Advertisement

Quick Links

Download this manual
Translation of the original operating manual
sb
Rev. 3.0 of 20/07/2022
Epsilon 2-6D LSCplus; ; ; ;
Version 07/2022
Epsilon 2-6D LSCplus
Part no. 111166
Freeze-dryer
Operating Manual
Read the manual thoroughly before use and retain it for later use!

Advertisement

Table of Contents
loading
Need help?

Need help?

Do you have a question about the Epsilon 2-6D LSCplus and is the answer not in the manual?

Questions and answers

Subscribe to Our Youtube Channel

Related Manuals for Christ Epsilon 2-6D LSCplus

Summary of Contents for Christ Epsilon 2-6D LSCplus

  • Page 1 Translation of the original operating manual Rev. 3.0 of 20/07/2022 Epsilon 2-6D LSCplus; ; ; ; Version 07/2022 Epsilon 2-6D LSCplus Part no. 111166 Freeze-dryer Operating Manual Read the manual thoroughly before use and retain it for later use!
  • Page 2 Freeze-dryer Epsilon 2-6D LSCplus Version 07/2022, Rev. 3.0 of 20/07/2022 • sb 2 / 156 Translation of the original operating manual...
  • Page 3 Freeze-dryer Epsilon 2-6D LSCplus In case of inquiries, please state the following numbers: Order number: Serial number: © Copyright by Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode am Harz Germany Tel.: +49 (0) 5522 / 5007-0...
  • Page 4 Freeze-dryer Epsilon 2-6D LSCplus Version 07/2022, Rev. 3.0 of 20/07/2022 • sb 4 / 156 Translation of the original operating manual...

  • Page 5: Table Of Contents

    Freeze-dryer Epsilon 2-6D LSCplus Table of contents General information ......................9 Importance of the operating manual .................. 9 Further applicable documents ................... 9 Intended use ........................9 1.3.1 Freeze-drying of solvent-containing products (non-aqueous media) ......11 1.3.2 Freeze-drying of acid-containing products ..............12 1.3.3...
  • Page 6 Freeze-dryer Epsilon 2-6D LSCplus Table of contents Safety notes concerning the operation ................32 3.7.1 Hazards caused by electricity ..................32 3.7.2 Hazards caused by natural, flammable refrigerants ........... 32 3.7.3 Hazards caused by nitrogen ..................33 3.7.4 Hazards caused by harmful products ................. 33 3.7.5...
  • Page 7 Freeze-dryer Epsilon 2-6D LSCplus Table of contents 5.2.5 Pressure control valve ....................52 5.2.6 Vacuum sensor ......................53 5.2.7 Drying cartridge (adsorption filter) ................54 Operation ..........................55 Initial start-up ........................55 Installation of accessories ....................55 Preparation ........................55 Switching the freeze-dryer on ..................
  • Page 8 Freeze-dryer Epsilon 2-6D LSCplus Table of contents Maintenance and service ....................116 Maintenance ......................... 116 8.1.1 General ........................116 8.1.2 Ice condenser chamber ................... 118 8.1.3 Drying chamber ....................... 118 8.1.3.1 Lamination of the loading door with a special film ..........118 8.1.3.2...

  • Page 9: General Information

    No unauthorised design modifications, additions or conversions without the written approval by Martin Christ Gefriertrocknungsanlagen GmbH have been performed. • The vacuum pump used is approved by Martin Christ Gefriertrocknungsanlagen GmbH. The vacuum pumps approved for this system are listed in chapter 5.2.4 - "Vacuum pump". •...
  • Page 10 Exclusion of liability Any use of the freeze-dryer other than the one described here or any use going beyond this description is regarded as improper use. Martin Christ Gefriertrocknungsanlagen GmbH cannot be held liable for any damage resulting from such improper use.

  • Page 11: Freeze-Drying Of Solvent-Containing Products (Non-Aqueous Media)

    Freeze-dryer Epsilon 2-6D LSCplus 1 General information Pos : 8 /200 C hrist/360 GT- BA Labor-Pil ot ( STAND ARDMODU LE) /010 Allgem eine Inform ationen/010- 0022-0010 Tr ock nung lös ungsmittelhaltiger Ausg angs produkte Labor+ Epsil on @ 89\m od_1648541810572_68.docx @ 942484 @ 3 @ 1 →...

  • Page 12: Freeze-Drying Of Acid-Containing Products

    Freeze-drying of azide-containing products Freeze-drying of products containing azides is only permissible following a case-by-case examination and the written approval by Martin Christ Gefriertrocknungsanlagen GmbH, since azides may form explosive dust- air-mixtures and also explosive metal azides when combined with non- ferrous metals (e.g.

  • Page 13: Copyright

    Pos : 16 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/010 Allgem eine Informationen/010- 0040 Ur heberrec ht @ 25\mod_1404983212403_68.doc x @ 182977 @ 2 @ 1 → Copyright The copyright concerning the operating manual remains with Martin Christ Gefriertrocknungsanlagen GmbH. The operating manual is solely intended for the operator and their personnel.

  • Page 14: Layout And Mode Of Operation

    Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Pos : 25 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/020 Aufbau und Wirk ungsw eise/020 Aufbau und Wirk ungsw eis e=========================== @ 25 \mod_1404983235994_68.doc x @ 183019 @ 1 @ 1 →...
  • Page 15 Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Connection bar for the product sensors Connection for the intermediate valve Intermediate valve Door latch (see chapter 8.1.3.2 - "Door latch") Shelf Fig. 2: Detailed view A – drying chamber Version 07/2022, Rev.
  • Page 16 Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation 10 Switch cabinet (behind the side panel) 11 Mains switch 12 Drying cartridge (adsorption filter, chapter 5.2.7 - "Drying cartridge (adsorption filter)" 13 Steerable castors Fig. 3:Right side of the freeze-dryer Version 07/2022, Rev.
  • Page 17 Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation 14 Aeration valve 15 Vacuum sensor (behind the side panel) 16 Sight glass of the ice condenser 17 Vacuum connection 18 Standard option: Precision control needle valve for gas injection 19 Access flanges DN40 (e.g.
  • Page 18 Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation 23 Filler neck for the heat transfer medium (with installed drying cartridge) 24 Main switch 25 Name plate (see chapter 2.1.2 - "Name plate") 26 Heat exchanger for the heat transfer...

  • Page 19: Name Plate

    Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Pos : 29 /200 C hrist/361 GT-BA Labor-Pilot (PR OJEKT E)/Epsilon 6er/Standar d/020 Aufbau und Wirkungsweis e/020- 0010-0020 Ty pensc hild E2-6D Standard 2.0 @ 25\m od_1404984799912_68.docx @ 186197 @ 3 @ 1 →...

  • Page 20: Mode Of Operation

    Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Pos : 31 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/020 Aufbau und Wirk ungsw eise/020-0020 Wirkungsweis e------------------------ @ 25\m od_1404983253850_68.docx @ 183047 @ 2 @ 1 → Mode of operation Pos : 32 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/020 Aufbau und Wirk ungsw eise/020-0020-0010 Gefriertrocknung allgem ein @ 25\mod_1404983254815_68.docx @ 183061 @ 3 @ 1...
  • Page 21 Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Fig. 8: Vapour pressure curve for ice and water From a physical point of view, the freeze-drying process covers three phases (see figure below): (1) Freezing: The product to be dried is frozen under atmospheric pressure.

  • Page 22: Freeze-Drying Process

    Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Fig. 9: Freeze-drying phases Please find further information about basic principles, optimum procedures and applications in the brochure "Smart freeze-drying", which can be downloaded at www.martinchrist.de → [Applications] → [Lyophilisation].

  • Page 23: Freezing

    Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Pos : 38 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/020 Aufbau und Wirk ungsw eise/020-0020-0020- 0020 Gefrier en Epsilon ( Lös ungsmittel z ulässig) @ 25\m od_1404983257955_68.docx @ 183103 @ 4 @ 1 →...

  • Page 24: Final Drying

    Freeze-dryer Epsilon 2-6D LSCplus 2 Layout and mode of operation Pos : 42 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/020 Aufbau und Wirk ungsw eise/020-0020-0020- 0040 Nac htr ock nung @ 25\m od_1404983260310_68.docx @ 183131 @ 4 @ 1 →...

  • Page 25: Safety

    Pos : 50 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0010 Besc hilderung des Geräts GT @ 25\m od_1404983297040_68.docx @ 183215 @ 2 @ 1 → Marking of the unit The following symbols are used for Christ freeze-dryers: Dangerous voltage On (Power)

  • Page 26: Explanation Of The Symbols And Notes

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 52 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0020 Symbol- und Hi nweis erklär ung en @ 25\mod_1404983298133_68.docx @ 183229 @ 2 @ 1 → Explanation of the symbols and notes...

  • Page 27: Responsibility Of The Operator

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 54 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0031 Ver antwortung des Betrei bers Epsilon Standard 2.0 @ 90\mod_1648641245328_68.docx @ 942767 @ 2 @ 1 → Responsibility of the operator...

  • Page 28: Freeze-Drying Of Solvent-Containing Products

    • ensure that the freeze dryer is operated with one of the vacuum pumps approved by Martin Christ Gefriertrocknungsanlagen GmbH (see chapter 5.2.4 - "Vacuum pump"). • have the system maintained at regular intervals (see chapter 8 - "Maintenance and service").

  • Page 29: Requirements Concerning The Personnel

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 58 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0041 Pers onalanforder ungen Epsilon allgemei n @ 25\m od_1404983300275_68.docx @ 183257 @ 2 @ 1 → Requirements concerning the personnel...

  • Page 30: Informal Safety Notes

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Qualified electrician Due to their special training, knowledge, experience and familiarity with the relevant standards and regulations, qualified electricians are in the position to perform work on electrical systems and to autonomously identify and prevent possible hazards.

  • Page 31: Hazards Caused By Improper Transport

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 66 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0020 Sic her heit Epsilon/030- 0060-0020 Gefahren durc h uns ac hgem äßen Transport @ 36\mod_1435840039491_68.docx @ 266725 @ 3 @ 1 3.6.2...

  • Page 32: Safety Notes Concerning The Operation

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 74 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0070 Si cherheits hinw eis e z um Betri eb @ 36\m od_1435842611820_68.docx @ 266767 @ 2 @ 1 Safety notes concerning the operation The following notes and instructions concerning the operation of the freeze- dryer must be observed in order to protect all persons and property.

  • Page 33: Hazards Caused By Nitrogen

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 80 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0020 Sic her heit Epsilon/030- 0070-0040 Gefahren durc h Sticks toff (Allgem ei n) @ 60\m od_1540884652312_68.docx @ 602426 @ 3 @ 1 3.7.3...

  • Page 34: Hazards Caused By Acids In The Products

    (e.g. a special vacuum pump) and following a case-by-case examination and the written approval by Martin Christ Gefriertrocknungsanlagen GmbH! Risk of poisoning caused by azides in the products When loading and unloading the shelves, the personnel are exposed to the product.

  • Page 35: Hazards Caused By Contaminated Condensate (Defrosting Water)

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 90 /200 C hrist/36 0 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0070-0090 Gefahren durch kontamini ertes Kondens at (Abtauwasser) @ 36\mod_1435902634359_68.docx @ 266885 @ 3 @ 1 3.7.8 Hazards caused by contaminated condensate (defrosting water)

  • Page 36: Oil-Sealed Vacuum Pump: Hazards Caused By Hot And Contaminated Vacuum Pump Oil

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 94 /200 C hrist/360 GT-BA Labor-Pilot (ST ANDARDM ODU LE)/030 Sic her heit/030-0020 Sic her heit Epsilon/030- 0070-0110 Gefahren durc h heiß es und kontamini ertes Vak uumpum penöl @ 36\m od_1435911705318_68.docx @ 266921 @ 3 @ 1 3.7.10 Oil-sealed vacuum pump: hazards caused by hot and contaminated vacuum...

  • Page 37: 3.7.13 Hazards Caused By The Loading Door

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 100 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/030 Sicherheit/030- 0020 Si cherheit Epsilon/030-0070- 0120 Gefahr en durch di e Bel adetür @ 36\m od_1435912260731_68.docx @ 266935 @ 3 @ 1 3.7.13 Hazards caused by the loading door...

  • Page 38: 3.7.17 Hazards Caused By Overpressure In The Chamber

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 108 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/030 Sicherheit/030- 0020 Si cherheit Epsilon/030-0070- 0160 Gefahr en durch Überdr uck ohne Ü berdrucksic her ung ( Standar d) @ 36\m od_1435915684375_68.docx @ 266991 @ 3 @ 1 3.7.17 Hazards caused by overpressure in the chamber...

  • Page 39: Procedures In The Event Of Hazards And Accidents

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Pos : 112 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMO DULE)/030 Sicherheit/030- 0020 Si cherheit Epsilon/030-0092 Ver hal ten bei Gefahr en und Unfäll en Epsilon ab 2-6D ++++++++++++++ @ 25\m od_1404983314476_68.docx @ 183439 @ 2 @ 1 →...

  • Page 40: Maintenance And Cleaning Of The Freeze-Dryer

    Freeze-dryer Epsilon 2-6D LSCplus 3 Safety Chemical burns: • Eyes: Rinse the eyes thoroughly with plenty of water with the lid gap wide open for at least 15 minutes (eyewash bottle). Consult an ophthal- mologist immediately even if there are no immediate symptoms. If possible, continue rinsing the eyes during the transport to the ophthal- mologist.

  • Page 41: Measures To Be Taken To Ensure Safe Operation Of The Freeze-Dryer

    • Stop the freeze-dryer immediately in the event of a malfunction. Eliminate the malfunction (see chapter 7 - "Malfunctions and error correction") or contact the after-sales service of Firma Martin Christ Gefriertrocknungsanlagen GmbH (see chapter 7.3 - "Service contact"). •...

  • Page 42: Remaining Hazards

    → 3.13 Remaining hazards All Christ freeze-dryers were built state-of-the-art and according to the accepted safety rules. Danger to life and limb of the operator, or of third parties, or impairments of the units or other material assets, however, cannot be completely excluded when the units are being used.

  • Page 43: Storage And Transport

    Freeze-dryer Epsilon 2-6D LSCplus 4 Storage and transport Pos : 123 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/040 Lag erung und Trans port/040 Lager ung und Tr ansport=========================== @ 25\m od_1404983713664_68.docx @ 183467 @ 1 @ 1 →...

  • Page 44: Unpacking The Freeze-Dryer

    DANGER • Prior to transporting the freeze-dryer, read this chapter of the operating manual thoroughly! The freeze-dryer Epsilon 2-6D LSCplus weighs approx. 330 kg! CAUTION The freeze-dryer is packaged in a wooden crate. • After opening the packaging, take out the accessories.

  • Page 45: Transport

    Prior to transporting the freeze-dryer, read this chapter of the operating manual thoroughly! The freeze-dryer Epsilon 2-6D LSCplus weighs approx. 330 kg! CAUTION Freeze-dryers of the type Epsilon 2-6D LSCplus that are filled with natural, flammable refrigerants are not approved as air freight! NOTE •...

  • Page 46: Transport Safety Devices

    Freeze-dryer Epsilon 2-6D LSCplus 4 Storage and transport Pos : 132 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/040 Lag erung und Trans port/040-0040-0011 Tr ansportsic her ung en Epsilon ( auß er 1-4/2- 4) @ 25\m od_1404984613792_68.docx @ 185637 @ 2 @ 1 →...

  • Page 47: Set-Up And Connection

    Freeze-dryer Epsilon 2-6D LSCplus 5 Set-up and connection Pos : 135 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/050 Aufstellung und Ansc hluss/050 Aufstellung un d Ans chl uss Epsilon/050 Aufstellung und Ansc hlus s Epsil on ========================== @ 36\mod_1436508805195_68.docx @ 267272 @ 1 @ 1 →...

  • Page 48: Supply And Disposal Connections

    Work on the power supply system must only be performed by certified electricians. WARNING Christ freeze-dryers are units of safety class I. Epsilon 2-6D LSCplus units have a five-wire power cord with a 5-pin CEE-plug (see chapter 10 - "Technical data").

  • Page 49: Aeration

    Freeze-dryer Epsilon 2-6D LSCplus 5 Set-up and connection Pos : 145 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/050 Aufstellung und Ansc hluss/050 Aufstellung und Ans chl uss Epsilon/050-0020- 0020 Belüftung Epsil on 1 Ansc hlus s @ 48\m od_1490090398173_68.docx @ 492320 @ 3 @ 1 →...

  • Page 50: Vacuum Pump

    Pos : 149 /200 Chris t/361 GT-BA Labor-Pil ot ( PROJ EKTE)/Epsilon 6er/Standard/050 Aufs tell ung und Ansc hluss /050-0020-0050 Vakuumpum pen E2- 6D @ 91\mod_1656940277886_68.docx @ 961573 @ 3 @ 1 Vak uumpumpe → 5.4.6 5.2.4 Vacuum pump For an intended use, the Epsilon 2-6D LSCplus freeze-dryer must be operated with one of the vacuum pumps listed below: Oil-sealed vacuum pumps: • Rotary vane pump Vacuubrand RZ6 •...

  • Page 51: Dry-Running Vacuum Pump And Silencer

    Freeze-dryer Epsilon 2-6D LSCplus 5 Set-up and connection Pos : 153 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/050 Aufstellung und Ansc hluss/050 Aufstellung und Ans chl uss Epsilon/050-0020- 0050-0020 Vak uum pumpe und Sc hall däm pfer (Troc kenläuferpum pen) @ 48\m od_1490092066628_68.docx @ 492438 @ 4 @ 1 Vac uum pum p →...

  • Page 52: Pressure Control Valve

    Freeze-dryer Epsilon 2-6D LSCplus 5 Set-up and connection Pos : 155 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/050 Aufstellung und Ansc hluss/050 Aufstellung und Ans chl uss Epsilon/050-0020- 0060 Drucks teuerventil Standard 2.0 ( auß er 2-4) @ 48\mod_1490093015317_68.doc x @ 492528 @ 3 @ 1 →...

  • Page 53: Vacuum Sensor

    Freeze-dryer Epsilon 2-6D LSCplus 5 Set-up and connection Pos : 157 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/050 Aufstellung und Ansc hluss/050 Aufstellung und Ans chl uss Epsilon/050-0020- 0070 Vak uumm esss onde neu - Ü berschrift--------------------------------- @ 48\mod_1490093443168_68.docx @ 492582 @ 3 @ 1 5.2.6...

  • Page 54: Drying Cartridge (Adsorption Filter)

    The silica gel of the drying cartridge has a limited adsorption capacity. If the colour of the silica gel changes from orange to green (see label on the drying cartridge), the drying cartridge must be replaced (Christ order no. 610 993).

  • Page 55: Operation

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 164 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/060 Betri eb======================================== @ 25\mod_1404983759758_68.doc x @ 183578 @ 1 @ 1 Operation Pos : 165 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/060-0011 Ers te Inbetriebnahm e Epsil on ++++++++++++++++++++++++++ @ 36 \mod_1436509116118_68.docx @ 267286 @ 2 @ 1...

  • Page 56: Loading Door

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 173 /200 Chris t/3 60 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/060-0050 Bel adetür Epsil on - Übersc hrift-------------------------------------- @ 25\m od_1404984628128_68.docx @ 185721 @ 2 @ 1 → Loading door Pos : 174 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/060-0050a Beladetür Acrylglas Text - Standard 2.0 @ 92\mod_1658308522573_68.doc x @ 967388 @ @ 1...
  • Page 57 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Radiation Shield film for loading doors made of acrylic glass Loading doors made of acrylic glass have a special, transparent film on the exterior side of the acrylic glass door. This film reduces the transfer of radiant heat onto the product and ensures homogeneous freeze-drying results.

  • Page 58: Lscplus Control System

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 176 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/LSC plus /060- 0050 LSC plus Anlagens teuerung Epsilon --------------------------------------------- @ 72\mod_1593154316973_68.doc x @ 766493 @ 2 @ 1 LSCplus control system The control system LSCplus (Lyo Screen Control plus) was specifically developed for the control of freeze-drying processes.

  • Page 59: Main Window "Manual

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation The user interface is divided into four main windows that can be called up by touching the corresponding buttons: Manual This window is also the standard user interface. It is used to control the freeze-drying process manually.
  • Page 60 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Status line (1) This line shows the operating status of the freeze-dryer as well as the active phase. The status line also shows the current date and time. The clock is battery- buffered and must be reset after a failure (see chapter 6.6.1.3 - "Main window "Options"", section "Administration").
  • Page 61 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Fig. 18: Dialog box "Select actual value" • Select the desired configuration or quit the dialog box by pressing the "return" button. In this way, it is possible to configure a personalised overview of the actual values.
  • Page 62 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Option: USB process recording (see chapter 6.7 - "Optional extensions and special equipment") • Select the "Process recording" function in the dialog box "Tools". • Select the input fields ("Batch data"). A keyboard for the data input will be displayed.
  • Page 63 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Fig. 21: Dialog box "Pressure increase test" • The "Test stop" button stops the pressure increase test. Option: LyoBalance weighing system If the freeze-dryer is equipped with a LyoBalance weighing system (see chapter 6.7 - "Optional extensions and special equipment"), then the corresponding parameters must be configured in this dialog box.
  • Page 64 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Dialog box "Process and equipment messages" (7) This dialog box shows and saves all of the error messages and other messages. In the event of an error or message, the window “Process and equipment messages” will open automatically. In addition, a sound signal is emitted until the error is acknowledged.
  • Page 65 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Details Touching the message calls up details concerning the error message: • Cause of the message, • Effects of the message, • Measures to eliminate the error, → Reference designator, • • Error counter (indicates how often this error has occurred) and the time stamp of the last error message.
  • Page 66 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Dialog box "Operating mode: select/start" (8) After the set values have been entered for the process, the process can be started manually with this function (see chapter 6.6.2 - "Manual freeze- drying"). Fig. 26: Dialog box "Operating mode: select/start" (The version of the dialog box that is displayed depends on the equipment of the freeze-dryer.)
  • Page 67 Fig. 28: Results of the performance test Evaluation: Please contact the Christ support team for the evaluation of the test run. Leakage test (2) The leakage test enables the chamber of the freeze-dryer to be tested for tightness in view of any gaseous or liquid media.
  • Page 68 • Select "Leakage test" and start the test via the "Run" button. The parameters for the leakage test have been developed by Martin Christ Gefriertrocknungsanlagen specifically for freeze-dryers. In a first step, these parameters (vacuum, ice condenser temperature) must be reached.
  • Page 69 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation At the end of the process, a pop-up window with a safety enquiry (confirmation prompt) opens. Following the confirmation of this enquiry, the freeze-dryer will be switched to standby. Evaluation: The test is passed if the dishes do not contain any water/ice after the end of the process.
  • Page 70 (confirmation prompt) opens. Following the confirmation of this enquiry, the freeze-dryer will be switched to standby. Evaluation: Please contact the Christ support team for the evaluation of the test run. Shelf mapping test (6) The shelf mapping test is a freeze-drying program for bringing the shelves to a temperature of +20°C, -40°C, and +40°C for a specific period of time in...
  • Page 71 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Button "Stop" (9) Pressing this button stops the current process. The system switches to the standby status. Pos : 186 /010 Univ ers almodul e/ Seitenwechs el @ 0\mod_1202116244312_0.docx @ 105 @ @ 1 Version 07/2022, Rev.

  • Page 72: Main Window "Program

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 187 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/LSC plus /060- 0050-0010- 0021 H auptfens ter Programm Epsilon @ 72\mod_1593154326974_68.doc x @ 766699 @ 4 @ 1 6.6.1.2 Main window "Program"...

  • Page 73: Main Window "Options

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 189 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/LSC plus /060- 0050-0010- 0031 H auptfens ter Optionen Epsilon - 1 Vakuumpum pe @ 72\m od_1593154328879_68.docx @ 766737 @ 4 @ 1 6.6.1.3...
  • Page 74 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Change scale unit (2) This dialog box is used to change the unit of measurement for the temperature and vacuum. Fig. 32: Dialog box "Change scale unit" Special equipment: Preselection of the aeration medium (3) This function can be performed in the manual mode or saved together with a program (see chapter 6.6.3.1 - "Creating a program").
  • Page 75 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation The following media preselection settings are possible: • Air: Preselects the media connection "Air". • Inert gas: Preselects the media connection "Inert Gas". • Automatic: Automatic media connection preselection depending on the chamber pressure and stoppering status of the product vials: –...
  • Page 76 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Special equipment: Inertisation (5) (see chapter 6.7 - "Optional extensions and special equipment") If the "Inertisation" option is active and the freeze-dryer is in the "Standby", "Manual - Freezing", "Program - Loading" or "Program - Freezing" mode, the automatic inertisation of the drying chamber will be performed for the preselected inertisation time after the loading door has been closed.
  • Page 77 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation If the volume flow through the inertisation line falls below a certain threshold for more than 5 seconds (the value can be preset at the flow meter) or if the loading door is opened during an inertisation sequence, the process will also be aborted immediately.
  • Page 78 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Network (2) This dialog box is used to change various system settings. The modifications will not become effective until after a restart of the unit. NOTE Fig. 38: Dialog box "Network" System properties (3) This dialog box is used to change various system settings.
  • Page 79 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Click on touch: If this function is active, a clicking sound can be heard whenever the system registers that a button has been touched. Behaviour of the pressure control valve in the case of insufficient ice condenser cooling: If this function is active (button "closed"), the pressure...
  • Page 80 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation • The button with the lock symbol blocks the access immediately and the system switches to the default setting. Fig. 42: Access blocked, the data cannot be edited Operator/maintenance/administrator password: For each of these access levels, certain editing rights have been defined.
  • Page 81 • Press the button "Add option". An input window opens. • Enter the six-digit Christ activation code that was supplied for this option. Note that the keys are case sensitive. Options can be removed in the same way. The modifications will not become effective until after a restart of the unit.
  • Page 82 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Product temperature sensor (see the illustration above, item B) Only for systems with a WTMplus system The wired product temperature sensor 1 is the default sensor for determining the value "ΔT product" (see chapter 6.6.3 - " Freeze-drying with the PGMplus programmer module ", section "Conditions for switching...
  • Page 83 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation WTMplus configuration (7) The dialog box is displayed for information purposes only. The configuration can be changed only via the LPCplus user interface. NOTE This dialog box shows all of the existing WTMplus sensors. Every sensor is assigned to a measuring channel based on its serial number.
  • Page 84 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Maintenance "Service" options: "Operating hours" "Failure memory" "Vacuum pump oil change" "Maintenance" "Sensor adjustment" Fig. 47: Dialog box "Service" (varies depending on the type of system) Operating hours (1) This dialog box is used to call up the number of operating hours of the various components of the freeze-dryer, e.g.
  • Page 85 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Failure memory (2) Equipment information system. These messages can be viewed in this dialog box. The failure memory includes the last 32 messages. If this number is exceeded, the oldest message will be overwritten.
  • Page 86 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Vacuum pump oil change (3) This option only applies to oil-sealed vacuum pumps! NOTE The system monitors the oil change interval of the vacuum pump. The interval can be adapted to the vacuum pump model and utilisation.
  • Page 87 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Maintenance (4) The maintenance interval of the unit is fixed at 3,000 operating hours or at least one maintenance per year. When the end of a maintenance interval is reached, a corresponding message will be displayed.

  • Page 88: Main Window

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 191 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/LSC plus /060- 0050-0010- 0041 H auptfens ter " ?" Epsilon @ 72\m od_1593154331423_68.docx @ 766775 @ 4 @ 1 6.6.1.4 Main window "?"...

  • Page 89: Entering Set Values In The Manual Mode

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation After the completion of a phase, the system switches to the next phase without switching the unit to standby. The transition from "freezing" to "warm-up" takes place automatically. After the completion of the warm-up phase, this dialog box will be displayed: Fig.
  • Page 90 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Viewing or editing the set values: • Press the button "Set values: view/edit" (see chapter 6.6.1.1 - "Main window "Manual""). The following dialog box will be displayed: "Aeration" button "Defrosting" button "Media drain" button (special equipment) "Leakage test"...

  • Page 91: Freeze-Drying With The Pgmplus Programmer Module

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Numerical values can be edited with the aid of a numerical keypad: Set value display Button for changing the sign (e.g. when entering temperature values) "" (infinite) Button for editing the value in pre-defined...
  • Page 92 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Fig. 56: Representation of a freeze-drying program Program sections When the programmer module executes a freeze-drying process, it executes the various sections that were created one after the other until the last section is completed.
  • Page 93 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Conditions for switching to the next section For all of the program sections to be executed automatically, certain switching conditions must be fulfilled at the end of each section. If these conditions are not fulfilled, e.g. due to incorrect set values, a corresponding process message will be displayed and the section will be extended.
  • Page 94 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation T comparative (option): This value indicates the difference between a Pirani sensor and a capacitive vacuum sensor in per cent based on the actual value of the capacitive vacuum sensor. When the sublimation rate decreases, the difference decreases as well.

  • Page 95: Creating A Program

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 199 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/LSC plus /060- 0050-0032- 0011 Programm erstellen Epsilon @ 72\m od_1593154338701_68.docx @ 766927 @ 4 @ 1 6.6.3.1 Creating a program To create a new program: •...
  • Page 96 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation "Program" buttons: "Program" "Program name" "Show diagram" "Insert section" "Delete section" Button for calling up more functions and set values "Save" Fig. 60: Editing a blank program template • The button “Delete section” (5) can be used to delete sections.
  • Page 97 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Button ">>more" The button ">>more" can be used to enter more functions and set values in a program-related manner. Fig. 61: Selection of program-related functions and set values Vacuum pump warm-up see chapter 6.6.3 - " Freeze-drying with the PGMplus programmer module "...
  • Page 98 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation next section is fulfilled and the next section will be initiated. If the condition for switching to the next section is not fulfilled, a process message will be issued, the current section will be extended, and further pressure increase tests will be executed periodically until the condition is fulfilled.
  • Page 99 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation → Option: Comparative pressure measurement (see chapter 6.7 - "Optional extensions and special equipment") The indication of the measurement value "dp Comp" can be configured in chapter 6.6.1.1 - "Main window "Manual"" under "Actual values of the current process"...
  • Page 100 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Option: LyoBalance weighing system If the freeze-dryer is equipped with a LyoBalance weighing system (see chapter 6.7 - "Optional extensions and special equipment"), then the corresponding parameters must be configured in this dialog box.
  • Page 101 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation "Aeration, (stoppering), storage" procedure: 1. Aeration up to the desired partial vacuum ("Aeration" value): After the actual freeze-drying process has been completed, the ice condenser continues to be cooled and the shelves are held at the temperature of the last drying section.
  • Page 102 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Special equipment: Preselection of the aeration medium If the freeze-dryer is equipped with an automatic aeration valve and automatic valves for media selection, this dialog box can be used to preselect the medium that is to be used for the aeration medium requests during the execution of the particular program.

  • Page 103: Editing A Program

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Program templates (2) The PGMplus programmer module offers various program templates that include recipes for all kinds of freeze-drying applications. They are suggestions for orientation purposes and must be adapted to the specific area of application of the freeze-dryer.

  • Page 104: Copying A Program

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 202 /010 Univ ers almodul e/ Leerz eile @ 0\mod_1202116244500_0.docx @ 114 @ @ 1 Pos : 203 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/LSC plus /060- 0050-0033- 0030 Programm kopi eren @ 72\m od_1593154340707_68.docx @ 766965 @ 4 @ 1 6.6.3.3...

  • Page 105: Deleting A Program

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Fig. 68: The freeze-drying process can be started with the aid of the button “Program start”. • During the freeze-drying process, the description of the active program can also be called up from the main window "Program" and via the button "Info".

  • Page 106: Optional Extensions And Special Equipment

    "Freezing" phase to support the cooling of the heat transfer fluid. This enables higher freezing rates This option is only available for freeze-dryers of the Epsilon 2-6D LSCplus and Epsilon 2-10D LSCplus type. Version 07/2022, Rev. 3.0 of 20/07/2022 • sb...
  • Page 107 Option: LPCplus SCADA System The Christ LPCplus system consists of the Supervisory Control And Data Acquisition (SCADA) software program by Martin Christ Gefriertrocknungsanlagen GmbH and a dedicated PC. The system is...
  • Page 108 Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Option: USB process recording see also chapter 6.6.1.1 - "Main window "Manual"", section "Dialog box "Tools"" This feature enables the recording of a running process on a USB storage medium. After the end of the process recording, the process data can be viewed on the PC with LyoLogplus and they can be printed.

  • Page 109: Switching The Freeze-Dryer Off

    Freeze-dryer Epsilon 2-6D LSCplus 6 Operation Pos : 212 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/060 Betrieb/060-0090 Auss chalten (Haupt- und Steuerungssc halter) +++++++++++++++++++++++++++ @ 25\m od_1404983765801_68.docx @ 183663 @ 2 @ 1 → Switching the freeze-dryer OFF The freeze-dryer must be in the standby status.

  • Page 110: Malfunctions And Error Correction

    Freeze-dryer Epsilon 2-6D LSCplus 7 Malfunctions and error correction Pos : 215 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/070 Störungen und F ehl ersuche/070 Störungen und F ehl ersuche=========================== @ 25\m od_1404984056039_68.docx @ 184111 @ 1 @ 1 →...

  • Page 111: Power Failure

    (see chapter 7.3 - "Service contact") If it is impossible to eliminate the errors, contact the Christ service department! NOTE Pos : 218 /010 Univ ers almodul e/ Leerz eile @ 0\mod_1202116244500_0.docx @ 114 @ @ 1 Pos : 219 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/070 Störungen und F ehl ersuche/070- 0010- 0010 Netzaus fall @ 25\mod_1404984058964_68.doc x @ 184153 @ 3 @ 1...

  • Page 112: Insufficient Vacuum

    Freeze-dryer Epsilon 2-6D LSCplus 7 Malfunctions and error correction Pos : 221 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/070 Störungen und F ehl ersuche/070- 0010- 0020 Kein ausr eichendes Vakuum @ 25\m od_1404984060039_68.docx @ 184167 @ 3 @ 1 →...

  • Page 113: Aeration Valve, Media Drain Valve

    Freeze-dryer Epsilon 2-6D LSCplus 7 Malfunctions and error correction Pos : 225 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/070 Störungen und F ehl ersuche/070- 0010- 0020-0022 Bel üftungs-, Medienabl aufv entil LSCpl us Epsilon (auß er 1-4/2-4) @ 36\mod_1436511271936_68.docx @ 267302 @ 4 @ 1 →...

  • Page 114: Insufficient Ice Condenser Temperature

    Freeze-dryer Epsilon 2-6D LSCplus 7 Malfunctions and error correction Pos : 231 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/070 Störungen und F ehl ersuche/070- 0010- 0031 Eisk ondensator- und Stellflächentem peratur Epsilon (auß er E1-4/2- 4) @ 25\m od_1404984665983_68.docx @ 185861 @ 3 @ 1 →...

  • Page 115: Service Contact

    Freeze-dryer Epsilon 2-6D LSCplus 7 Malfunctions and error correction Pos : 235 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/070 Störungen und F ehl ersuche/070- 0031 Kontak t im Servic efall_Epsil on @ 25\m od_1404984069705_68.docx @ 184293 @ 2 @ 1 →...

  • Page 116: Maintenance And Service

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 238 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080 Wartung und Instandhaltung D elta, Epsil on 2- 6D, 2-10D =========================== @ 25\m od_1404984095704_68.docx @ 184307 @ 1 @ 1 →...
  • Page 117 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Cleaning of the freeze-dryer Risk of burns on hot surfaces Housing of the freeze-dryer During the operation of the freeze-dryer and half an hour afterwards, the outer surface of the freeze-dryer (especially the pipes and units) may be WARNING hot.

  • Page 118: Ice Condenser Chamber

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 243 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0010- 0021 Eisk ondensatork ammer Epsilon (auß er E2- 4) @ 25\m od_1404984098898_68.docx @ 184349 @ 3 @ 1 →...

  • Page 119: Door Latch

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Do not clean the film while dry. CAUTION • Use soft cloths, soft sponges made of synthetic fibres or rubber squeegees and common household cleaning agents (glass cleaner) for cleaning. The cleaning agents must be free from abrasive agents.

  • Page 120: Aeration Valve, Media Drain Valve

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 251 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0010- 0052 Belüftungs-, M edienablaufventil Epsil on (auß er 1- 4/2-4) @ 36\mod_1436512125085_68.docx @ 267317 @ 3 @ 1 →...

  • Page 121: Heat Exchanger (Only Air-Cooled Freeze-Dryers)

    Check the heat exchanger at least once per month for soiling and clean it if necessary. • Please contact the Christ service department if you have any queries (see chapter 7.3 - "Service contact"). Pos : 254 /010 Univ ers almo dul e/ Leerz eile @ 0\mod_1202116244500_0.docx @ 114 @ @ 1...

  • Page 122: Vacuum System With An Oil-Sealed Vacuum Pump

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 257 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0010- 0082 Vak uumsy stem Epsil on ( Vakuumpum pen mit Öl) @ 36\m od_1436512296280_68.docx @ 267332 @ 3 @ 1 →...

  • Page 123: Vacuum System With A Dry-Running Vacuum Pump

    The number of operating hours of the vacuum pump can be monitored by way of the LSCplus control system and also by way of the CHRIST SCADA software LPCplus (see chapter 6.6.1.3 - "Main window "Options""/"Operating hours"...

  • Page 124: Refrigeration System

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 261 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0010- 0091 Kältesystem Epsilon (natürliche, brennbare Kältemittel) @ 64\m od_1558595727235_68.docx @ 690977 @ 3 @ 1 8.1.9...

  • Page 125: Vacuum Sensor

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 265 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0010- 0120 Vak uumm esss onde allgemei n @ 25\m od_1404984105610_68.docx @ 184433 @ 3 @ 1 →...

  • Page 126: Disinfection Of The Drying Chamber And Accessories

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Disinfection of the drying chamber and accessories If dangerous materials (e.g. infectious and pathogenic substances) are used, the freeze-dryer and accessories must be disinfected. DANGER  • Use commercially-available disinfectants such as, for example, Incidur ...

  • Page 127: Maintenance Schedule (Oil-Sealed Vacuum Pump)

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 271 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0032 W artungs plan Epsil on 6er 10er (Vak uum pumpen mit Öl) @ 25\m od_1404984681385_68.docx @ 185931 @ 2 @ 1...
  • Page 128 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component Stainless steel door sight glasses: clean, illumination ok Acrylic glass door: surface clean and undamaged Machinery – Switch cabinet general Leakages...
  • Page 129 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component springs: service life of 10 years Final vacuum Vacuum leak test Refrigeration Icing of components system Pressure readings / performance tests...
  • Page 130 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component Test sample (visual Water content of inspection, freezing heat transfer medium point, boiling point) Replace insulation Heat exchanger: (Armaflex) at heat...
  • Page 131 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component Switch cabinet: Replacement of the 1 year filter cooling system Wiring Power reading of components LSCplus control Replacemant of the 6 years...

  • Page 132: Maintenance Schedule (Dry-Running Vacuum Pump)

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 273 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0033 W artungs plan Epsil on 6er 10er (Troc kenläuferpum pen) @ 45\m od_1475738266045_68.docx @ 443614 @ 2 @ 1...
  • Page 133 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component Stainless steel door sight glasses: clean, illumination ok Acrylic glass door: surface clean and undamaged Machinery – Switch cabinet general Leakages...
  • Page 134 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component 9,000 Silencer: Exchange of the filter operating element Filter element hours Final vacuum Vacuum leak test Refrigeration Icing of components system...
  • Page 135 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component Test sample (visual Water content of the inspection, freezing heat transfer medium point, boiling point) Replace insulation Heat exchanger: (Armaflex) at heat...
  • Page 136 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service System/ Detail / Part Inspection Periodical Maintenance Repair / Rebuild Component Switch cabinet: Replacement of the 1 year filter cooling system Wiring Power readings of components LSCplus control Replacemant of the 6 years...

  • Page 137: Service

    Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service Pos : 275 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/080 W artung und Instandhaltung/080-0041 Ins tandhaltungs arbeiten Epsilon (mit W artungsv ertrag nur de) @ 25\m od_1404984109982_68.docx @ 184489 @ 2 @ 1...
  • Page 138 Freeze-dryer Epsilon 2-6D LSCplus 8 Maintenance and service 1. Declaration of decontamination As a certified company and due to the legal regulations for the protection of our employees and of the environment, we are obliged to certify the harmlessness of all incoming goods. For this purpose, we require a declaration of decontamination.

  • Page 139: Disposal

    Pos : 281 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/090 Entsorgung/090-0010 Entsorgung der Gefriertr ock nungsanlag e @ 25\m od_1404984141122_68.docx @ 184531 @ 2 @ 1 → Disposal of the freeze-dryer Martin Christ Gefriertrocknungsanlagen GmbH is a registered manufacturer of electric and electronic devices that are solely intended for commercial use.

  • Page 140: 10 Technical Data

    Freeze-dryer Epsilon 2-6D LSCplus 10 Technical data Pos : 286 /200 Chris t/361 GT-BA Labor-Pil ot ( PROJ EKTE)/Epsilon 6er/Standard/100 Technisc he Daten/100 T ec hnisc he D aten E2-6D Standard 2.0 =================================== @ 25\m od_1404984843551_68.docx @ 186295 @ 1 @ 1 →...

  • Page 141: Ambient Conditions

    Freeze-dryer Epsilon 2-6D LSCplus 10 Technical data Performance data Ice condenser - Capacity: 6 kg max. - Performance: 4 kg / 24 h max. approx. –85°C - Temperature: Drying chamber - Dimensions (W x H x D): 320 mm x 320 mm x 335 mm - Volume: approx.

  • Page 142: 11 Appendix

    Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 294 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/110 Anhang/0110 Anhang================================================= @ 25\m od_1404984177994_68.docx @ 184601 @ 1 @ 1 → 11 Appendix Pos : 295 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/110 Anhang/0110-0010 Mathematische Z us ammenhänge @ 25\m od_1404984178952_68.docx @ 184615 @ 2 @ 1 →...

  • Page 143: Ec Declaration Of Conformity In Accordance With The Ec Machinery Directive

    Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 297 /200 Chris t/361 GT-BA Labor-Pil ot ( PROJ EKTE)/Epsilon 6er/Standard/110 Anhang/0110- 0030 CE-Erkl ärungMasc hR L 2-6D _LSC plus Standard 2.0 @ 25\m od_1404984852837_68.docx @ 186321 @ 2 @ 1 →...
  • Page 144 Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 298 /010 Univ ers almodul e/ Seitenwechs el @ 0\mod_1202116244312_0.docx @ 105 @ @ 1 Version 07/2022, Rev. 3.0 of 20/07/2022 • sb 144 / 156 Translation of the original operating manual...

  • Page 145: Ec Declaration Of Conformity In Accordance With The Pressure Equipment Directive

    Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 299 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/110 Anhang/0110-0031 CE- Erklär ung Dr uckger äteRL @ 38\m od_1438592143048_68.docx @ 275085 @ 2 @ 1 11.3 EC declaration of conformity in accordance with the Pressure Equipment Directive Version 07/2022, Rev.
  • Page 146 Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 300 /010 Univ ers almodul e/ Seitenwechs el @ 0\mod_1202116244312_0.docx @ 105 @ @ 1 Version 07/2022, Rev. 3.0 of 20/07/2022 • sb 146 / 156 Translation of the original operating manual...

  • Page 147: Table Of The Sublimation Pressure Curve

    Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 301 /200 Chris t/360 GT-BA Labor-Pil ot ( STAND ARDMODULE)/110 Anhang/0110-0021 T abelle Sublim ations druc kkurv e @ 25\mod_1404984180168_68.doc x @ 184629 @ 2 @ 1 11.4 Table of the sublimation pressure curve °C...
  • Page 148 Freeze-dryer Epsilon 2-6D LSCplus 11 Appendix Pos : 302 /010 Univ ers almodul e/ Abs chnittswec hs el @ 0 \mod_1202124514062_0.docx @ 418 @ @ 1 Pos : 303 /010 Univ ers almodul e/ Seitenwechs el @ 0\mod_1202116244312_0.docx @ 105 @ @ 1 Version 07/2022, Rev.

  • Page 149: 12 Glossary

    Since absolutely tight components simply do not exist, a leak rate is determined. The parameters for the leakage test have been developed by Martin Christ Gefrier- trocknungsanlagen GmbH specifically for freeze-dryers. In a first step, these parameters (vacuum, ice condenser temperature) must be reached.
  • Page 150 Safety pressure Since the vacuum has a dominating influence on the product temperature, Martin Christ Gefriertrocknungsanlagen GmbH has integrated a so-called safety pressure feature into the freeze-dryers in order to ensure the protection of the product. If the pressure inside the drying chamber increases too strongly so that it exceeds the safety limit, the energy supply of the shelves will be interrupted and the →...

  • Page 151: 13 Index

    Freeze-dryer Epsilon 2-6D LSCplus Index 13 Index CE mark in compliance with the directive 2006/42/EC ..........25 Access protection........79 Changing of operating supplies ....40 Accessories ....... 41, 116, 125 Chemical burns .......... 39 Accident prevention ......27, 30 Chemical reactions ........
  • Page 152 Freeze-dryer Epsilon 2-6D LSCplus Index Damage to the materials of construction .. 116 EC declaration of conformity (Machinery Directive) ........13, 143 Danger of infection due to exhaust air ..51 EC declaration of conformity (Pressure Danger of poisoning due to exhaust air ..51 Equipment Directive) ......
  • Page 153 Freeze-dryer Epsilon 2-6D LSCplus Index Freezing ............. 23 Health and safety rules and regulations and regulations for the prevention of accidents Functional and operating elements .... 14 ............27, 29 Further applicable documents ...... 9 Heat emission .......... 140 Heat exchanger ........121 Gas injection with a proportional valve 75, 108 Heat transfer media .........
  • Page 154 Freeze-dryer Epsilon 2-6D LSCplus Index LPCplus SCADA System ......107 Mode of operation ........20 LSCplus control system ......58 Monitoring camera system LyoCam ..107 Lyes ............40 LyoBalance weighing system ..... 63, 108 Name plate .......... 19, 48 LyoCam monitoring camera system ..
  • Page 155 Freeze-dryer Epsilon 2-6D LSCplus Index Option: Wireless product temperature Radioactive substances ......117 measurement system WTMplus ... 106 Rated current ..........19 Optional equipment ........106 Reference designator ..... 63, 65, 84, 150 Refrigerant ..........140 Refrigerant data ......... 19, 140 Packaging ..........
  • Page 156 Freeze-dryer Epsilon 2-6D LSCplus Index Signs of corrosion ........125 Transport safety devices ......46 Silencer and vacuum pump (dry-running) .. 51 Transport to commissioning (hazards, general) ..........30 Single-chamber method ......150 Type........... 19, 140 Small flange connections ......112 Solvent-containing products .......

This manual is also suitable for:

111166

Table of Contents