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Related Manuals for ADInstruments ML1001
Summary of Contents for ADInstruments ML1001
- Page 1 INSTRUMENTS making science easier ML1001 Electronic Stimulator Owner’s Guide...
- Page 2 INSTRUMENTS making science easier ML1001 Electronic Stimulator Owner’s Guide...
- Page 3 This document was, as far as possible, accurate at the time of release. However, changes may have been made to the software and hardware it describes since then. ADInstruments Pty Ltd. reserves the right to alter specification as required. Late-breaking information may be supplied separately.
- Page 4 This alerts the user to imminent death or serious injury arising DANGER from misuse of the stimulator. This alerts the user to possible death or serious injury arising WARNING from misuse of the stimulator. This alerts the user to possible injury or damage to property CAUTION arising from misuse of the stimulator.
- Page 5 GENERAL HANDLING PRECAUTIONS This device is intended for use only by qualified medical personnel. Use only our approved products with this device. Use of non-approved products or in a non- approved manner may affect the performance specifications of the device. This includes, but is not limited to, batteries, recording paper, pens, extension cables, electrode leads, input boxes and AC power.
- Page 6 CAUTION United States law restricts this device to sale by or on the order of a physician. Operator’s Manual 1001...
- Page 7 EMC RELATED CAUTION This equipment and/or system complies with the International Standard IEC 60601-2 for electromagnetic compatibility for medical electrical equipment and/or system. However, an electromagnetic environment that exceeds the limits or levels stipulated in IEC 60601-1-2, can cause harmful interference to the equipment and/or system or cause the equipment and/or system to fail to perform its intended function or degrade its intended performance.
- Page 8 8. Use of unspecified configuration: When the equipment and/or system is used with the unspecified system configuration different than the configuration of EMC testing, it may cause increased electromagnetic emission or decreased electromagnetic immunity. Only use this equipment and/or system with the specified configuration. 9.
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Page 10: Table Of Contents
Contents Specifications ..........28 Introduction ........... 2 Stimulation Trigger........... 28 Features ............2 Main Interval............28 Configuration ............. 3 Stimulation Waveform Setup ......28 Peripheral Devices ..........3 Stimulation Output ........... 29 Electronic Stimulator 1001 Hardware Configuration ..4 Synchronized Output Signal ......30 Precautionary Labels and Indications ... -
Page 11: Introduction
Introduction The electronic stimulator is used for the basic physiological and pharmacological research and experiments. WARNING This device is designed for experimental and research applications and must not be used for therapeutic purposes. By simple operation of the panel, a single pulse, pair pulse, train pulse and repeat pulse according to main interval can be output, as well as various mixed waveforms in combination with an external signal, and a biphasic pulse. -
Page 12: Configuration
Configuration Peripheral Devices PowerLab TRIG to ISO Electronic Stimulator 1001 OUTPUT Isolator Patch Clamp Amplifier Microelectrode Amplifier Membrane Potential Fixing Amplifier [Fig.1] Introduction 3... -
Page 13: Electronic Stimulator 1001 Hardware Configuration
Electronic Stimulator 1001 Hardware Configuration F-ROM for writing Serial 1 Communications Unit SCI-A EEPROM Settings TRIG LEVEL Stimulation Output Voltage Stimulation Signal Isolator Range Amplifier Information Stimulation Voltage (Detected Value) [Fig.2] 4 Introduction... -
Page 14: Precautionary Labels And Indications
Precautionary Labels and Indications See the relevant reference page for details of each label or indication. CAUTION If this instrument is connected to other peripheral devices, be sure that they are connected in the manner specified by the manufacturer. Only connect devices specified by the manufacturer. Connection to non-specified devices may result in electric shock to the operator by current of leakage. -
Page 15: List Of Symbols
List of Symbols The following symbols are used in connection with the stimulator. An explanation of each symbol is given in the table below. * When the description of a symbol used for the stimulator differs from JIS standards, it is shown in brackets. Symbol Description Symbol... -
Page 16: Description Of Parts
Description of Parts Front Stimulation Waveform Output Memory Main Interval Stimulation Waveform Setup [Fig.5] Power On/Off External Trigger Biphasic•EMixing•EModulation•EDC Dial Power On/Off This button is used to turn the power on and off. [Fig.6] Name Function 1Power Button When the power button is pressed (ON position), the power indicator lamp 2Power Indicator Lamp lights and the power is turned on. -
Page 17: Main Interval
Main Interval Controls the repeat cycle (T1) and repeat count (N1) as well as starting and stopping of stimulation. (The timing signal created here acts becomes the trigger as MAIN INTERVAL and is not a direct stimulation waveform.) [Fig.8] Name Function 5Stimulation interval (T1) Displays the repeat interval (T1) setting. - Page 18 Name Function AMAIN INTERVAL operation lamp Lights when MAIN INTERVAL is operating. (As it is sometimes difficult to tell whether MAIN INTERVAL is operating when a long interval has been set, operation can be judged by checking the lamp.) Disabled MAIN INTERVAL signal...
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Page 19: External Trigger (Ext Trig)
External Trigger (EXT TRIG) Like MAIN INTERVAL, this generates a trigger pulse. It is used to control the stimulation repeat cycle by an external signal. When EXT is selected with the trigger selector button, stimulation occurs in synchronization with the signal that is input to the external trigger terminal on the rear of the stimulator. - Page 20 Name Function BTrigger level adjustment knob Selects whether the trigger is activated at the signal level that is input to the (EXT TRIG LEVEL) external trigger terminal (on rear). Adjustment range: 0 to ±10 V. If the sweep-wave output from the oscilloscope is used as the external trigger signal, the stimulation pulse can be monitored at any position on the oscilloscope tube by setting the level adjustment knob.
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Page 21: Stimulation Waveform Setup
Stimulation Waveform Setup This component receives the main interval trigger signal, external trigger signal, etc., sets the stimulation wave and timing and sends the signal for stimulation output. The stimulation wave is determined by the four parameters in the figure below. - Page 22 Name Function CTrigger signal selector key Selects a trigger signal. The lamp for the selected key lights. (MAIN, EXT) MAIN: Signal generated by MAIN INTERVAL described above EXT: Signal generated by EXTERNAL TRIGGER described above DDelay time display Sets the delay time (T2) until the channel outputs a stimulation pulse after the (DELAY) trigger signal is received.
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Page 23: Stimulation Waveform Output
Stimulation Waveform Output This sets the polarity of the waveform generated by stimulation waveform setup and the output voltage. [Fig.15] Name Function IPolarity selector key Switches the polarity of the stimulation pulse. indicates positive polarity , OFF, negative polarity. The selection governs both the isolator connector and the output terminals. Output is 0 V when OFF is selected. - Page 24 Name Function KOutput selector key When the key is pressed, the lamp lights and 5 times the normal voltage of 0 to (±50 V / ±10 V) ±10 V is supplied to the output terminal. This can be used for field stimulation. (max.
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Page 25: Biphasic, Mix, Modu, Dc, Altn
BIPHASIC, MIX, MODU, DC, ALTN These keys are used when stimulation is performed by biphasic wave, a composite wave created by mixing with an external waveform, a waveform where the external signal has been modulated by internal oscillation, or with DC voltage. O P QRS [Fig.17] Function... - Page 26 Name Function QWaveform modulation key Press this key to modulate the external signal to the waveform created in (MODU) stimulation waveform setup described above. (The lamp lights.) Connect the modulated signal to the MODU terminal on the rear of the stimulator. The VOLTAGE setting is disabled when this key is pressed.
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Page 27: Memory
Memory Settings can be saved for retrieval later. [Fig.20] Function Name TMemory keys To save the settings, press P1 or P2 for more than 2 seconds. The current settings are saved to the selected memory. (P1, P2) Pressing P1 or P2 briefly later will retrieve and apply the saved settings. 18 ... -
Page 28: Rear
Rear INPUT OUTPUT MAIN MAIN KEY MAIN SET CYCLES START START STOP INTERVAL TRIG SPEAKER AC SOURCE TRAIN TRIG MODU DELAY INTERVAL [Fig.21] External input Synchronization signal Power terminals output terminals Power AC SOURCE [Fig.22] Name Function 1Equipotential ground terminal Connect the ground wires of accessory devices to ground the devices. -
Page 29: External Signal Input Terminals
External Signal Input Terminals [Note] Input the signals to the input terminals in the range specified in the input conditions. If the signal exceeds the range, it may cause failure or malfunction. INPUT OUTPUT MAIN MAIN KEY MAIN SET CYCLES START START STOP... - Page 30 Name Function 8Mixing signal input terminal Input the desired signal to this terminal to combine it with an external signal (MIX) when performing stimulation. The mixed signal can be obtained by pressing the MIX key on the front panel after connecting the signal. /Input conditions Input impedance: approx.
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Page 31: Synchronizing Signal Output Terminal
Synchronizing Signal Output Terminal The following signal is provided as a synchronizing signal for other devices. The synchronizing signal is output regardless of the MIX, MODU or DC polarity selector keys or the VOLTAGE setting. For example, even when the DC key is pressed and no pulse is output, the END and DELAY pulses are output according to stimulation waveform setup. -
Page 32: Serial Output
name Function Delay signal output terminal Generates a pulse that is synchronized with the delay signal generated by (DELAY) stimulation waveform setup. (See Fig.12 for the timing.) Interval signal output terminal Generates a pulse that is synchronized with the interval. (See Fig.12 for the (INTERVAL) timing.) Train end signal output terminal... -
Page 33: General Handling Precautions
General Handling Precautions CAUTION The electronic stimulator has a high voltage output capacity of up to ±50 V. Directly touching the output terminals or electrodes during stimulation or when the power cable is connected during inspection and the stimulator is operable may result in electric shock. - Page 34 The output terminal has a short-circuit protective circuit, but avoid short- circuiting for long periods as this may adversely affect the performance of the stimulator. When the power is turned on, output is momentarily unstable and a spike pulse may be generated. When stimulating, this spike may become the stimulation pulse.
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Page 35: Preparation
Preparation Installing the Stimulator Take the following precautions when installing the stimulator. Avoid contact with water or chemicals. Also, avoid direct contact with mist or humidified air from a humidifier as this may cause malfunction or reduce the service life of the stimulator. Keep out of direct sunlight as this may result in an unexpected rise in temperature, causing malfunction or reducing the service life of the stimulator. - Page 36 When stimulating with the isolator, connect the isolator to the [to ISO] output connector. [Note] /When connecting the isolator, tighten the screw firmly to prevent the cable from coming loose. /When connecting the stimulation output cable, connect the cable securely to prevent it from coming loose. If necessary, connect an oscilloscope and recorder and data acquisition/ analysis system, etc.
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Page 37: Specifications
Specifications Stimulation Trigger Main Interval (1) START A) MANUAL switch (front panel) B) START INPUT (rear) Input pulse: +3.5 V or over, 10 µs or over Input impedance: 10 kilohms or over C) Short-circuit of KEY terminal (rear) and E terminal 2) STOP A) MANUAL switch (front panel) B) STOP INPUT (rear) -
Page 38: Stimulation Output
4) TRAIN Setting range: 1 to 999 Continuous operation when set to “run” Stimulation Output 1) Output polarity and OFF Polarity switch: Positive/negative polarity (No effect on MODULATION or MIXING polarity) OFF: No output to ISOLATOR or OUTPUT 2) MODULATION Amplitude: Depends on amplitude of external signal including polarity (Max. -
Page 39: Synchronized Output Signal
7) ±50 V output Linearity: 0 to ±5 V, within ±100 mV ±5 V to ±50 V, within ±5% Output impedance: 10 ohms or less Output waveform: 7 µs or less both rising and falling Excessive deviation: 10% or less Maximum output current: 400 mA or over Synchronized Output Signal 1) Output signal name... -
Page 40: Durability
Durability 6 years (based on self-certification of company data) Installation Indoor installation type Safety Standards Applicable safety standards: IEC 60601-1 IEC 60601-1-2 :2001 Type of protection against electrical shock: Class I Degree of protection against electrical shock where attached: B applied parts Degree of protection against harmful ingress or liquids: IPX0 (devices w/o special protection) Mode of operation: Continuous operation... - Page 41 Guidance and manufacture’s declaration - electromagnetic emissions This Model 1001 is intended for use in the electromagnetic environment specified below. The customer or the user of the 1001 should assure that it is used in such an environment. Emissions test Compliance Electromagnetic environment guidance The 1001 uses RF energy only for its internal function.
- Page 42 Guidance and manufacture’s declaration - electromagnetic immunity This Model 1001 is intended for use in the electromagnetic environment specified below. The customer or the user of the 1001 should assure that it is used in such an environment. IEC 60601 test Electromagnetic environment - guidance Immunity test Compliance level...
- Page 43 Recommended separation distances between portable and mobile RF communications equipment and the 1001 This Model 1001 is intended for use in the electromagnetic environment in which radiated RF disturbances are controlled. The customer or the user of the 1101 can help prevent electromagnetic interference by maintaining a minimum distance between portable and mobile RF communications equipment (transmitters) and the 1001 as recommended below, according to the maximum output power of the communications.
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