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For automated sample collection, the Auto Sampling option is available which
is comprised of a sampling manifold with sampling and return cannulas. The
manifold may also include the AutoTemp option which includes individual
temperature probes for each dissolution vessel.
For a hands-free test start, the newly designed Dosage Delivery Module (DDM)
allows for simultaneous or sequential introduction of dosage forms. Lastly, a
Printer may be included to document all critical apparatus settings and events.
2. Instrument Setup
2.1. Physical Setup
Once the 708-DS dissolution apparatus has been delivered to the laboratory
where setup and installation will occur, the steps to begin unpacking and any
applicable qualification begin. The following sections will proceed naturally
through various procedures to ensure a smooth and methodical setup.
2.1.1. Unpacking Equipment / Accessories
Upon delivery of the equipment, some portions of the apparatus will
require some simple assembly. It is important to first inspect all pieces to
ensure no damage has occurred during shipment. The following table
includes many, if not all, of the accessories shipped with the unit:
708-DS Dissolution Apparatus
Power Cords
Bath Temperature Probe
Dissolution Vessels
TruAlign™ Blank Vessel Position Covers
DDM Assemblies
Cover Aligners
DDM Alignment Shafts
Shaft Locking Collars
17-mm Open End Wrench
7/64" T-Handle Allen Wrench
Length of Plastic Tubing (1/2" OD)
Clip-on Basket Height Gauge
Technical Documentation CD
Revision A
P/N: xx-xxxx
Agilent 708-DS Dissolution Apparatus
Heater / Circulator
6-pin Cable for Heater / Circulator
External Vessel Temperature (EVT) Probe
Evaporation Covers
Evaporation Cover Plugs
Basket Shaft Assemblies
Paddle Shaft Assemblies
Vessel Centering Tool
Thermal Printer Paper
90° Allen Key (for Level Adjustment)
Stainless Steel Tubing Clamps
25-mm Spheres
Bubble Level
Rinse Cups
- 7 -
Training Manual
September 2010
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