Epson STYLUS SCAN 2500 Manual page 124

8. Place the ink cartridge gently into the cartridge holder with
the label on the cartridge facing up. Do not press down on the
cartridge.
9. Press the ink cartridge clamp down until it locks in place.
c
10. Close the maintenance cover and the document cover.
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Caution:
Once you install the ink cartridges, do not open their clamps
again until you are ready to replace the cartridges. Lifting
the clamps makes the cartridges unusable.