Infors HT Minifors 2 Manuals

Infors HT Minifors 2 Manuals

Manuals and User Guides for Infors HT Minifors 2. We have 2 Infors HT Minifors 2 manuals available for free PDF download: Operating Manual

Infors HT Minifors 2 Operating Manual

Infors HT Minifors 2 Operating Manual (234 pages)

Bench-Top Bioreactor

Brand: Infors HT | Category: Laboratory Equipment | Size: 23 MB

Table of Contents

Supplemental Directives
3
Table of Contents
4
Safety and Responsibility
13
Other Messages
13
Intended Use, Incorrect Use and Misuse
14
Unauthorised Persons
15
Responsibility of the Provider
16
Residual Risks
16
Warning Symbols on the Device
18
Declaration of Decontamination
19
Setup and Function
20
Basic Unit
20
Overview
20
Operating Panel
21
Power Switch
21
LED Strip - Status Indicator
21
Mains Connection
22
Water Connections
22
Gas Connections
23
Signal Connections
23
Motor Cable Connection
25
Connections for Sensors (Sensor Cables)
25
Gassing Connection
26
Connections Exit Gas Cooler and Valve for Water
26
Flow
26
Pumps
27
Identification Plate
28
Culture Vessel
29
Overview
29
Top Plate
30
Ports in the Vessel Top Plate
31
Temperature Control System
34
Stirrer
35
Overview
35
Motor
35
Impeller
37
Gassing System
38
Ph Control
39
Control
41
Antifoam Control
43
Options
44
Turbidity Measurement
44
Setup and Function
44
Mounting the Turbidity Sensor
46
Exit Gas Analysis
47
Setup and Function
47
Connecting the Gas Sensor
47
Redox Measurement
49
Balances
50
Accessories
51
Accessories in the Scope of Delivery
51
Cone Plug for Drive Hub
52
Sparger
52
Baffles
53
Blanking Plugs
53
Clamping Adapters and Fastening Screws
54
Sensor Holder
55
Addition Port Adapters and Feed Needles
55
Septum Collar
57
Dip Tubes
57
Immersion Pocket for Temperature Sensor (Pt100)
58
Exit Gas Cooler
59
Cold Finger
61
Reagent Bottles
62
Sampling System Super Safe Sampler
63
Pump Heads
65
Vessel Holder
66
Sterile Filters
67
Hoses and Accessories
69
O-Rings and Gaskets
70
Inoculation Accessories and Tools
70
Starter Set
71
Service Sets
71
Auxiliary Supplies
71
Transport and Storage
72
Transport
72
Storage
72
Installation and Commissioning
73
Operating Conditions at the Installation Location
73
Minimum Distances to the Device
73
Connecting the Device to On-Site Supply Lines
73
Power Supply
74
Water Supply and Return
74
Gas Supply
75
Exit Gas
76
Connecting the Motor Cable
76
Test Run
77
Before Cultivation
82
Preparing the Culture Vessel
82
Checking Gaskets (O-Rings)
82
Mounting the Impellers
83
Mounting Dip Tubes and Spargers
84
Inserting the Vessel into the Vessel Holder
85
Inserting the Baffles
86
Moistening/Filling the Culture Vessel
86
Mounting the Top Plate
87
Mounting the Blanking Plugs
88
Mounting Addition Port Adapters
89
Mounting the Feed Needles
89
Mounting the Immersion Pocket for Temperature
90
Sensor (Pt100)
90
Equipping a Port with Septum Collar and Septum for Inoculation
90
Preparing the Dip Tube / Addition Port Adapter for Inoculation
92
Mounting the Exit Gas Cooler
92
Mounting the Cold Finger
93
Preparing the Sensors
94
Calibrating the Ph Sensor
95
Mounting Sensors into 12 MM Ports
95
Mounting Sensors with Sensor Holder
96
Mounting the Antifoam Sensor
98
Preparing the Sampling System Super Safe Sampler
99
Mounting the Sparger Hose and the Inlet Air Filter
100
Space Gassing
101
Preparing the Reagent Bottles, Pumps and Hoses
102
Sterile Hose Connections
105
Setting the Pumps
105
Removing the Pump Heads
105
Fitting the Cone Plug for Drive Hub
106
Autoclaving the Culture Vessel
107
Checklist before Autoclaving
107
Autoclaving
108
Connecting the Culture Vessel and Preparing the Cultivation
110
Pump Heads
110
Filling the Reagent Hoses
110
Connecting the Gassing
111
Connecting the Exit Gas Cooler
112
Connecting the Cold Finger
112
Coupling the Motor
112
Filling the Culture Vessel
113
Connecting the Temperature Sensor (Pt100)
114
Connecting the Antifoam Sensor
114
Connecting the Ph Sensor
115
Connecting the Po
115
Sensor
115
Calibrating the Po
116
Sensor
116
Checking the Hoses and Hose Connections
116
Cultivation
117
Preparing the Medium
117
Sampling
117
Inoculation
121
Inoculation with a Syringe
121
Inoculation Using Dip Tube / Addition Port Adapter
122
Harvest
122
Emptying the Culture Vessel
123
Emptying the Reagent Hoses
124
Autoclaving the Culture Vessel after Cultivation
125
Operation
127
Screen Areas, Menu Navigation and Control Elements
127
Overview
127
Main Screen
128
Edit View
130
Start Batch / Inoculate / Stop Batch
131
Sample Now
132
Menus for System Settings
134
Overview
134
VESSEL TYPE - Selecting a Culture Vessel
135
APPEARANCE - Display Settings
136
Network Settings
138
EVE COMMUNICATION - Communication Settings
139
USB Data Export and Import from a USB Stick
140
SYSTEM INFO - System Information
143
Parameter - Parameter Groups
144
Overview
144
Parameters - Displays and Functions
145
SETPOINT - Setting the Setpoint
146
Parameter Alarms
147
Cascades
149
MAIN Parameter Group
150
Temperature
150
Stirrer
151
Total Flow
155
Gasmix
155
Foam
156
EXTENDED Parameter Group
158
Balance (Optional)
158
Flow Parameters
159
Turbidity (Optional)
161
Redox (Optional)
161
Analog IO1 & Analog IO2
161
EXIT GAS Parameter Group
163
Exit Gas O
163
Exit Gas CO
163
PUMPS Parameter Group
164
Overview
164
Configuring the Pumps
165
Pump1
167
Pump2
167
Pump3
167
Pump4
168
AUTO FILL/EMPTY - Automatically Filling/Emptying Pump Hoses
169
Calibrating the Sensors
171
Calibrating the Ph Sensor
171
Ph Sensor Product Calibration
175
Calibrating the Po
177
Sensor
177
Calibrating the Turbidity Sensor
180
PID Controller - Basic Principle
182
Tips for Readjusting a PID Controller
183
Adjusting PID Settings
183
Alarms - Equipment Alarm Menu
184
Switching off the Device
185
10 Cleaning and Maintenance
186
Cleaning Agent and Disinfectant
186
Cleaning the Culture Vessel - Routine Cleaning
187
Removing the Vessel Top Plate and Accessories
188
Removing the Exit Gas Cooler
188
Removing the Sensors
190
Removing Hoses, Filters and Pump Heads
190
Removing Blanking Plugs
191
Removing the Septum Collar and Septum
191
Removing Addition Port Adapters, Feed Needle and Temperature Sensor Immersion Pocket
192
Removing the Vessel Top Plate
192
Removing the Sparger and the Dip Tube(S)
193
Removing the Impellers
193
Cleaning and Storing Individual Parts
194
Cleaning the Sensors
195
Cleaning the Hoses and Pump Heads
195
Cleaning the Super Safe Sampler
195
Cleaning the Basic Unit and Operating Panel
196
Maintenance Plan
196
10.10 Decalcifying the Device
197
11 Rectifying Faults
199
General Faults
199
Faults Drive System
200
Faults Temperature Control System
201
Faults Gassing System
202
Faults Ph Control
204
Faults Po
206
Control
206
Faults Antifoam/Level and Pump
207
Faults Feed and Pump
208
Interferences Turbidity Measurement
209
Replacing Device Fuses
210
Behaviour in Case of a Power Interruption
210
Returning for Repair
210
12 Disassembly and Disposal
211
Disassembly
211
Disposal
211
13 Technical Data
213
Dimensions
213
Weight
217
Connections and Connection Values
217
Electrical Connection and Power Values
217
Water
218
Process Gas
219
Specifications of the Basic Unit
219
Operating Panel
219
Culture Vessel
219
Stirrer
221
Temperature Control System
224
Gassing System
225
Ph Control
227
Control
228
Antifoam Control
228
Pumps
229
Specifications of the Options
229
Turbidity Measurement
229
Exit Gas Analysis
230
Redox Measurement
230
Operating Conditions
231
Emissions
231
14 EU Declaration of Conformity
232
EG-Konformitätserklärung
233

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Infors HT Minifors 2 Operating Manual

Infors HT Minifors 2 Operating Manual (217 pages)

Benchtop Bioreactor

Brand: Infors HT | Category: Laboratory Equipment | Size: 8 MB

Table of Contents

Table of Contents
3
1 General Information

11
- About this Manual
  11
- Explanation of Special Notices
  11
  - Warning Notices
    11
  - Other Notices
    12
- Equipment Identification (Standard Identification Plate)
  12
- Declaration of Conformity
  13
- Customer Service and Services
  13
2 Safety and Responsibility

14
- Intended Use, Incorrect Use and Misuse
  14
- Qualified Personnel
  15
  - Provider
    15
  - User
    15
  - Operator
    16
- Unauthorised Persons
  17
- Responsibility of the Provider
  17
- General Hazards
  17
  - Electrical Current
    18
  - Unauthorised Spare Parts and Accessories
    18
- Particular Hazards
  18
  - Hot Surfaces
    19
  - Dangerous Gases
    19
  - Flammable or Explosive Substances
    19
  - Corrosive or Toxic Substances
    19
  - Bioactive Substances or Pathogenic Organisms
    20
  - Overpressure or Vacuum
    20
- Warning Symbols on the Equipment
  20
- Declaration of Decontamination
  21
3 Setup and Function

22
- Basic Unit
  22
  - Main Switch
    23
  - LED Strip
    23
  - Pumps
    23
  - Identification Plate
    24
  - Power Connection
    25
  - Water Connections
    25
  - Gas Connections
    25
  - Signal Connections
    26
  - Motor Cable Connection
    26
  - Connections for Sensors (Sensor Cables)
    27
  - Sparger Connection (Gassing)
    27
  - Connections and Water Flow Control Valve for the Exit Gas Cooler
    28
- Operating Panel
  29
- Culture Vessel
  29
- Temperature Control System
  35
- Stirrer
  36
- Gassing System
  37
  - Gas Entry
    38
  - Exit Gas
    38
- Ph Control
  38
  - Measurement System
    38
- Po Control
  39
  - Measurement System
    40
- Antifoam Control
  41
  - Antifoam Sensor
    41
4 Options

42
- Turbidity Measurement
  42
  - Sensors
    43
  - Calibrating the Zero Point
    43
  - Mounting the Sensor
    44
  - Cleaning and Storing the Sensor
    44
  - Interferences Turbidity Measurement
    45
  - Specifications
    45
- Exit Gas Analysis
  46
  - Gas Sensors
    46
  - Connecting the Gas Sensor
    46
  - Calibrating the Gas Sensor
    47
5 Accessories

48
- Cone Plug for Drive Hub
  48
- Sparger
  49
- Baffles
  49
- Blanking Plugs
  50
- Clamping Adapters and Fastening Screws
  50
- Electrode Holder
  51
- Addition Port Adapters and Feed Needles
  52
- Septum Collar
  53
- Dip Tubes
  53
- Pocket for Temperature Sensor (Pt100)
  54
- Exit Gas Cooler
  55
- Reagent Bottles
  56
- Sampling System Super Safe Sampler
  56
- Pump Heads
  59
- Vessel Holder with Built-In Holder for Reagent Bottles and Pumps
  60
- Sterile Filters
  60
- Hoses and Accessories
  62
- O-Rings and Gaskets
  63
- Inoculation Accessories and Tools
  63
- Starter Kit
  64
- Service Sets
  64
- Auxiliary Supplies
  64
6 Transport and Storage

65
- Transport
  65
- Storage
  66
7 Installation and Initial Operation

67
- General Location Requirements for Installation
  67
- Minimum Distances
  67
- Connecting the Equipment to On-Site Supply Lines
  67
  - Power Supply
    68
  - Water Supply and Return
    68
  - Gas Supply
    69
  - Exit Gas
    70
- Connecting the Motor Cable
  70
- Test Run
  71
  - Preparation Test Run
    71
  - Cooling System
    72
  - Stirring
    73
  - Heating and Adjusting Temperature
    73
  - Gassing
    74
  - End of Test
    74
8 Before Cultivation

76
9 Cultivation

110
- Preparing the Medium
  110
- Sampling
  111
- Inoculation
  114
  - Inoculation with a Syringe
    115
  - Inoculation Using Dip Tube / Addition Port Adapter
    115
- Harvest
  116
- Emptying the Culture Vessel
  117
- Emptying the Reagent Hoses
  117
- Switching off the Equipment
  117
- Autoclaving the Culture Vessel after Cultivation
  118
10 Operation

120
- Screen Areas, Menu Navigation and Control Elements
  120
  - Main Screen
    122
  - Edit View
    123
  - Start Batch / Inoculate / Stop Batch
    124
  - Sample Now
    125
- Menus for System Settings
  126
- Parameter - Parameter Groups
  136
  - Parameters - Displays and Functions
    137
  - SETPOINT - Setting the Setpoint
    139
  - Parameter Alarms
    140
  - Cascades
    142
- MAIN Parameter Group
  143
  - Temperature
    143
  - Stirrer
    143
  - Po 2
    145
  - Totalflow
    148
  - Gasmix
    148
  - Foam
    149
- EXTENDED Parameter Group
  151
  - Turbidity (Optional)
    151
  - Balance (Optional)
    151
  - Airflow
    151
  - Gas2Flow
    152
- EXITGAS Parameter Group
  153
  - Exit Gas O
    153
  - Exit Gas CO
    154
- PUMPS Parameter Group - General Information
  154
- Calibration
  161
- PID Controller - Basic Principle
  180
  - Useful Information for Changing PID Controller Settings
    182
  - Adjusting PID Settings
    183
- Alarms - Equipment Alarm Menu
  183
11 Cleaning and Maintenance

185
- Cleaning Agent and Disinfectant
  185
- Cleaning the Culture Vessel - Routine Cleaning
  185
- Removing the Vessel Top Plate and Accessories
  187
- Cleaning and Storing Individual Parts
  191
  - Removing the Impellers
    191
- Cleaning the Sensors
  192
- Cleaning the Hoses and Pump Heads
  192
- Cleaning the Super Safe Sampler
  193
- Cleaning the Exit Gas Cooler
  193
- Cleaning the Basic Unit and Operating Panel
  194
- Maintenance Plan
  194
- Decalcifying the Equipment
  195
12 Interferences

197
- Interferences Basic Unit and Operating Panel
  197
- Interferences Drive System
  198
- Interferences Temperature Control System
  199
- Interferences Gassing System
  199
- Interferences Ph-System
  200
- Interferences Po
  202
  - System
    202
- Interferences Antifoam/Level Sensor and Antifoam
  203
  - Pumps
    203
- Interferences Addition of Feed Solution (Feed Pump)
  204
- Returning for Repair
  204
13 Disassembly and Disposal

205
- Disassembly
  205
- Disposal
  205
14 Technical Data

207
- Equipment Dimensions
  207
- Dimensions of Culture Vessel
  208
- Weights (Netto)
  209
- Connection Requirements
  209
  - Electrical
    209
  - Water IN, Basic Unit
    209
- Water OUT, Basic Unit
  209
- Gas (Air, O 2 or N 2 )
  210
- Specifications
  210
  - Operating Panel
    210
  - Culture Vessels
    210
  - Stirrer
    211
  - Temperature
    212
  - Gassing
    213
  - Antifoam
    214
  - Pumps
    215
- Operating Conditions
  215
- Emissions
  215
- Auxiliary Supplies
  216

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