Infors HT Techfors-S Manuals

Manuals and User Guides for Infors HT Techfors-S. We have 1 Infors HT Techfors-S manual available for free PDF download: Operating Manual

Infors HT Techfors-S Operating Manual (284 pages)

Pilot scale bioreactor

Brand: Infors HT | Category: Laboratory Equipment | Size: 30 MB

Supplemental Directives
3
Table of Contents
5
Safety and Responsibility
15
Other Messages
15
Intended Use, Incorrect Use and Misuse
16
Unauthorized Persons
18
Responsibility of the Provider
18
Residual Risks
18
Warning Symbols on the Device
21
Declaration of Decontamination
22
Basic Unit
23
Additional Information
24
Operating Panel
25
Harvest/Sample Valve (Bottom Valve)
42
Setup and Function
42
Using the Harvest/Sample Valve
44
Vessel Pressure Display (Manometer)
48
Setup and Function
48
Mounting the Manometer
48
Stirrer
49
Setup and Function
49
Coupling and Uncoupling the Motor
52
Lubricating the Mechanical Seal
54
Temperature Control System and Sterilization
55
Setup and Function
55
Mounting the Temperature Sensor
58
Gassing System
59
Setup and Function
59
Removing and Mounting the Inlet Air Filter
63
Exit Gas System
64
Setup and Function
64
Exit Gas Filter
66
Cleaning the Exit Gas Cooler
68
Ph Control
70
Setup and Function
70
Mounting and Connecting the Ph Sensor
71
Control
73
Setup and Function
73
Mounting and Connecting the Po Sensor
74
Antifoam Control
77
Setup and Function
77
Preparing the Antifoam Sensor for Cultivation
77
Mounting and Connecting the Antifoam Sensor
80
Mounting the Vessel Safety Valve
83
Identification of the Device
85
Identification Plate
85
Plant Identification Plate
85
Vessel Identification Plate
86
Options
87
Overview of the Options
87
Additional Information
87
Sample Valve
88
Setup and Function
88
Using the Sample Valve
89
Resterilizable Feed Line
90
Setup and Function
90
Preparing the Resterilizable Feed Line
91
Steam Generator
94
Switching between Tap Water/Chilled Water
95
Recirculating Chiller
95
Lifting Device for Vessel Top Plate
96
Level Detection
97
Setup and Function
97
Mounting and Connecting the Level Sensor
97
Pressure Control
100
Setup and Function
100
Maintenance
100
Mounting and Connecting the Pressure Sensor
100
Weight Measurement Vessel - Load Cell
102
Turbidity Measurement
103
Setup and Function
103
Mounting and Connecting the Turbidity Sensor
104
Exit Gas Analysis
105
Pco 2 Measurement
107
Redox Measurement
108
Permissive Measurement
109
Pumps
109
Balances
110
Mobile CIP Unit Techcip
110
Accessories, Material and Hoses
111
Overview of the Accessories
111
Starter Set
111
Connection Set
112
Reagent Bottles
113
Setup and Function
113
Preparing Reagent Bottles for Cultivation
114
Specifications
116
Push Valves
117
Setup and Function
117
Preparing Push Valves for Cultivation
118
Specifications
120
Inoculation Needles
121
Setup and Function
121
Preparing Inoculation Needles for Cultivation
122
Specifications
124
Vessel Light
124
Setup and Function
124
Mounting the Vessel Light
125
Transport and Storage
127
Transport
127
Transportation Safety Device
128
Storage
128
Installation and Commissioning
129
Operating Conditions at the Installation Location
129
Minimum Distances to the Device
130
Requirements for the Mains Connection
130
Requirements for Connections and Interfaces
130
Safety Valves
133
Cultivation
134
Preparing the Bioreactor
134
In Situ Sterilization
137
Preparing the Medium
138
Sampling
138
Inoculation
138
Harvest
139
Emptying the Vessel
139
Sterilization after Cultivation
139
Operation
141
Overview Screen, Menu Navigation and Control Elements
142
Main Menus
145
Main - Overview
145
Batch - Start Menu
148
Controller - Value Display
149
Cascades
151
Trends - Trend Lines
152
System - System Settings
153
Alarms - Alarm Display
155
Menu Overview
155
Parameter Alarms
156
Overview of System Alarms
156
Additional Information
156
Submenus
158
Valves - Digital Controller Outputs
158
Security - User Administration
159
Menu Overview
159
User Groups
159
Access Rights
160
(Own) Password
165
New User - Adding a New User
166
Edit User - Changing User Settings
167
Remove User - Deleting a User
168
Set / Clear Default User - Setting up Automatic User Login
168
Password Security - Setting Password Rules
169
Settings - Basic Settings of the Device
171
Menu Overview
171
IP-Settings - Network Settings
172
Change Time
173
Backup - Saving Data
174
Restore - Restoring Data Backups
175
Export Logs - Exporting Log Files
177
Balance Settings
178
Wipe Screen - (Temporarily) Locking the Screen
180
Shutdown - Shutting down the System
181
Recipes
182
General Information
182
Save Recipe
182
Load/Start Recipe
182
Delete Recipe
183
Parameters
185
Parameter Options
190
Overview of Settings Menu
190
Setpoint
191
Menu Content
191
Setting Setpoints, Activating and Deactivating Parameters
192
Setting Alarm Limits and Critical Values
194
Calibrate
195
Menu Content
195
General Information on Calibrating
195
Calibrating a Digital Ph Sensor
196
Product Calibration of a Digital Ph Sensor
199
Calibrating an Analog Ph Sensor
201
Recalibrating an Analog Ph Sensor
204
Calibrating Digital a Po Sensor
205
Calibrating an Analog Po Sensor
208
Calibrating the Turbidity Sensor
209
PID Controller Settings
210
Menu Content
210
PID Control Explained
211
Tips for Readjusting a PID Controller
213
Tare Weight Function - Taring the Weight Display
214
Cascade Control
215
Cascade Control Explained
215
Setting a Cascade
216
Menu and Functions
216
Cascade Progress Display
218
Deleting a Cascade
219
Special Configurations
220
Pumps
221
Control and Settings
221
Calibrating the Pumps
221
Resetting the Pump Counter to Zero
223
Filling and Emptying the Pump Hoses
224
Processes
226
General Information
226
Safety Notes
227
Full Sterilization
228
Process Sequence
228
Process Configuration
229
Before Starting the Process
230
Executing the Process
230
Terminating the Process
231
Aborting the Process
232
Sample Valve
232
Process Sequence
232
Process Configuration
232
Before Starting the Process
233
Executing the Process
233
Aborting the Process
234
SIP Sample Valve - Sterilization Sample Valve
234
Process Sequence
234
Process Configuration
234
Before Starting the Process
235
Executing the Process
235
Aborting the Process
236
SIP Feed Line - Sterilization Feed Line
236
Process Sequence
236
Process Configuration
236
Before Starting the Process
237
Executing the Process
237
Aborting the Process
238
Bioreactor Operation - Cultivation
239
Process Sequence
239
Process Configuration
239
Before Starting the Process
240
Starting the Process
240
Terminating the Process
241
Shutting down the System; Switching off the Device
242
Gency
243
Switching on Again after Emergency Stop
243
Rectifying Faults
244
Fault Tables
244
General Faults
244
Faults Drive System
245
Faults Temperature Control System
246
Faults Gassing System
247
Faults Ph Control
248
Faults Po
250
Control
250
Faults Antifoam Control
251
Faults Feed and Pump
252
Interferences Turbidity Measurement
253
Behavior in Case of a Power Interruption
253
Returning for Repair
254
10 Cleaning and Maintenance
255
Cleaning Agent and Disinfectant
255
Cleaning the Bioreactor
256
Maintenance Plan
257
11 Disassembly and Disposal
260
Disassembly
260
Disposal
260
12 Technical Data
262
Dimensions
262
Connections and Connection Values
263
Specifications of the Basic Unit
265
Instrumentation Cabinet
265
Operating Panel
265
Vessel
265
Temperature Control System
267
Stirrer
268
Gassing System
269
Components
269
Gassing Variants
271
Exit Gas System
272
Ph Control
272
Control
274
Antifoam Control
275
Pumps
275
Vessel Pressure Display (Manometer)
276
Safety Valves
277
Specifications of the Options
277
Steam Generator
277
Recirculating Chiller
278
Level Detection
278
Pressure Control
279
Weight Measurement Vessel - Load Cell
279
Turbidity Measurement
280
Exit Gas Analysis
280
Pco
281
Measurement
281
Redox Measurement
281
Permissive Measurement
282
Operating Conditions
282
Operating Materials
282

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