Bayer HealthCare CONTOUR NEXT User Manual page 36

Principles of the Procedure:
glucose test is based on measurement of electrical current
caused by the reaction of the glucose with the reagents on
the electrode of the strip. The blood sample is drawn into
the tip of the test strip through capillary action. Glucose
in the sample reacts with FAD glucose dehydrogenase
(FAD-GDH) and a phenothiazine derivative as a mediator.
Electrons are generated, producing a current that is
proportional to the glucose in the sample. After the reaction
time, the glucose concentration in the sample is displayed.
No calculation is required.
Comparison Options: C
ONTOUR
should be done with venous and capillary whole blood.
Comparison to a laboratory method must be done
simultaneously with aliquots of the same sample. Note:
Glucose concentrations drop rapidly due to glycolysis
(approximately 5% to 7% per hour).
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The C N blood
ONTOUR EXT
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Limitations
Preservatives: Blood may be collected by health care
professionals into test tubes containing heparin. Do not use
other anticoagulants or preservatives.
Peritoneal Dialysis Solutions:
with C ® N test strips.
ONTOUR EXT
Interference: Reducing substances occurring in the blood
naturally or from therapeutic treatments will not significantly
affect results. See reagent test strip insert for more
information.
Xylose: Do not use during or soon after xylose
absorption testing. Xylose in the blood will cause
an interference.
References
1. Wickham NWR, Achar KN, Cove DH. Unreliability of
capillary blood glucose in peripheral vascular disease.
Practical Diabetes. 1986; 3(2): 100.
2. Atkin S, et al. Fingerstick Glucose Determination in Shock.
Ann Intern Med. 1991; 114: 1020-1024.
3. Desachy A, Vuagnat AC, et al. Accuracy of Bedside
Glucometry in Critically Ill Patients: Influence of Clinical
Characteristics and Perfusion Index. Mayo Clin Proc.
2008; 83(4): 400-405.
4. Longo DL, et al. Harrison's Principles of Internal Medicine,
18th Edition, 2011. http://www.accessmedicine.com
5. Tietz Fundamentals of Clinical Chemistry, 5th Edition,
Edited by Burtis CA and Ashwood ER, W. B. Saunders Co.,
Philadelphia, PA, 2001, p. 444.
Icodextrin does not interfere
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