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Please read this manual thoroughly to familiarize yourself with the
many unique features and exciting innovations we have built into
your new equipment. Esco provides many other resources at our
website, www.escolifesciences.com, to complement this manual
and help you enjoy many years of productive and safe use of your
Esco products.
For Technical Service, contact
North America
Esco Technologies, Inc.
903 Sheehy Drive, Suite F, Horsham, PA 19044, USA
Toll-Free USA and Canada 888-375-ESCO
Tel 215-441-9661 • Fax 484-698-7757
www.escolifesciences.us •
eti.sales@escolifesciences.com
Rest of World
Esco Micro Pte. Ltd.
21 Changi South Street 1 • Singapore 486777
Tel +65 6542 0833 • Fax +65 6542 6920
www.escolifesciences.com • mail@escolifesciences.com
Esco Cytoculture
Cytotoxic Safety Cabinet A Series Customized User Manual
Version A - Released March 2024
User Manual
Cytotoxic Safety Cabinet
Model Code : CYT-_A1
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Related Manuals for Esco Cytoculture CYT-A1 Series
Summary of Contents for Esco Cytoculture CYT-A1 Series
- Page 1 Please read this manual thoroughly to familiarize yourself with the many unique features and exciting innovations we have built into your new equipment. Esco provides many other resources at our website, www.escolifesciences.com, to complement this manual and help you enjoy many years of productive and safe use of your Esco products.
- Page 2 Esco makes no representations or warranties as to the accuracy of the information contained in this manual. In no event shall Esco be held liable for any damages, direct or consequential, arising out of or related to the use of this...
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Page 3: Table Of Contents
Table of Contents INTRODUCTION Table of Contents Warranty Terms and Conditions Introduction 1. Products Covered 2. Safety Warning 3. Document Management 4. Limitation of Liability 5. European Union Directives on WEEE and RoHS 6. Symbols USER SECTION Chapter 1 - Introduction 1.1 Unit Identification Labels Chapter 2 - Product Information 2.1 Quick View (CYT A Series) - Page 4 6.1.2 Operating Motorized Sash Window 6.1.3 Using Sash Window 6.2 Starting and Shutting Down the Cabinet 6.3 Working in the Cabinet 6.4 Working Ergonomics 6.5 UV Lamps (If Present) 6.6 Decontamination and Disinfecting Agents 6.7 Gaseous Decontamination Chapter 7 - Service and Maintenance 7.1 Scheduled Maintenance 7.2 Maintenance/Service Log Cytotoxic Safety Cabinet...
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Page 5: Warranty Terms And Conditions
Esco, were defective at the time of being sold and that all defective parts shall be returned, properly identified with a Return Authorization. - Page 6 For international distributors, warranty period starts two months from the date the equipment is shipped from Esco facility. This allows shipping time so the warranty will go into effect at approximately the same time the equipment is delivered to the user. The warranty protection extends to any subsequent owner during the warranty period.
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Page 7: Products Covered
If you require replacements for any of the provided documentation (including factory test reports) you can request copies from Esco Customer Services*. Please provide the following information when making requests for replacement documents: •... - Page 8 The disposal and / or emission of substances used in connection with this equipment may be governed by various local regulations. Familiarization and compliance with any such regulations are the sole responsibility of the users. Esco’s liability is limited with respect to user compliance with such regulations. 5. European Union Directive on WEEE and RoHS The European Union has issued two directives: •...
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Page 9: Unit Identification Labels
Chapter 1 - Introduction 1.1. Unit Identification Labels The first label will contain: Model : The model of the unit Serial : The serial number of the unit Power : The maximum power consumption and the electrical requirement of the unit Manufactured in : The month and year when the unit was manufactured The second label will contain: The model of the unit... - Page 10 The third label will contain: The third label is usually located next to the Cabinet power inlet. This label contains the electrical requirement needed to operate the unit...
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Page 11: Chapter 2 - Product Information
Chapter 2 - Product Information 2.1. Quick View (CYT A Series) Cytotoxic Safety Cabinet... -
Page 12: Airflow Pattern
2.2. Airflow Pattern / Activated carbon filter / HEPA filter • Air enters the cabinet through perforations located along the front of the work zone before mixing with used downflow air in a common chamber below the work zone (this inflow air does not mix with the filtered downflow air in the cabinet’s main chamber). -
Page 13: Chapter 3 - Installation
The following requirements should be taken into account: • If necessary, the arm rest and sash cover can be removed to reduce the overall depth of the cabinet. Detailed instructions on how to carry out this step can be obtained from your Esco Service Representative. •... - Page 14 For proper exhaust filter leak scanning purposes (only for CYT A Series), a minimum clearance of 50 cm (1’ 8’’) is recommended. Esco does not guarantee that this distance would be sufficient. It would have to be verified by your nearest Esco distributor or your service company.
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Page 15: Optional Retrofit Kit
The following is a list of retrofit kits available for this unit, you may also want to visit www.escolifesciences.com for more information. Accessories and Options Esco offers a variety of options and accessories to meet local applications. Contact Esco or your local sales representative for ordering information. Accessory / Option Description •... -
Page 16: Installation
• Ergonomic footrest - Angled, helps maintain proper posture. - Adjustable height- Anti-skid coating, chemical resistant finish. • IV bar, with hooks - Stainless steel construction - Available for all standard Esco cabinets Installation 3.3. 3.3.1. Connecting the Electrical Supply •... -
Page 17: Performance Validation/Certification
The testing methods and equipment’s needed for carrying out the tests are specified on the test report accompanying your cabinet. 3.4.1. Disclaimer The performance and safety of all Esco cabinet are rigorously evaluated at our factory. Regular field certification is important to ensure factory standards are maintained. 3.4.2. References for Qualified Certifiers North America •... -
Page 18: Chapter 4 - Handling Cytotoxic Drugs
Chapter 4 - Handling Cytotoxic Drugs Based on USP General Chapter <800> Hazardous Drugs – Handling in Healthcare Settings, health care workers who work with or near cytotoxic drugs may be exposed to these agents in the air or on work surfaces, clothing or medical equipment. - Page 19 Cleaning Step Purpose Agents Decontamination Remove hazardous drug Materials that have been validated to be residue effective for hazardous drug decontamination, or through other materials proven to be effective through testing, which may include alcohol, water, peroxide, or sodium hypochlorite Cleaning Remove organic and Germicidal detergent...
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Page 20: Chapter 5 - Sentinel Control System
Chapter 5 - Sentinel Control System 5.1. Sentinel Control System 1. Fan Button Turns on and turn off the fan blower. 2. Light Button Turns on and turn off the fluorescent lamps. Light goes on automatically when sash is at the operating position, READY state. Light goes off automatically when sash is at SASH ALARM state. -
Page 21: 13 5.2 Menu Options
To go back to the previous level of the menu options. To access maintenance mode from ERR.MSWITCH and AIRFAIL! error condition. 5.2. Menu Options Please refer to the following diagram for complete reference to all menu options available. SET TIME WARM UP POST PURGE SETTINGS... - Page 22 UV timer can be used to switch off the UV lamp automatically after a fixed period. The UV timer can be set up to 18 hours. By default, the timer is set to 60 minutes. Esco does not recommend leaving the UV lamp on for more than 60 minutes per decontamination cycle as it shortens the lifespan of the UV lamp.
- Page 23 ZERO SENSOR CALIB SENSOR 5.2.2.1. Set Constant Every sensor manufactured by Esco has a specific Sensor Constant which is used for temperature compensation by the temperature sensor. 5.2.2.2. Zero Sensor This option is to let the controller record the specific sensor output voltage and correspond it to 0 m/s or 0 fpm.
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Page 24: Alarms And Warnings
However, if the problem continues, the operator should stop working as the Cabinet’s protection may have been compromised. Call service or Esco’s local distributor. Other alarms that indicate a failure or an error in the Cabinet system: •... -
Page 25: Chapter 6 - Basic Cabinet Operation
Chapter 6 - Basic Cabinet Operation 6.1. Sash Window Operation 6.1.1. Sash Window State Sash is fully open Sash is in safe position Sash is fully closed ✓ Blower can be activated ✓ Blower can be activated Blower can’t be activated ✓... - Page 26 6.1.3. Using Sash Window • The sash window should be fully closed when the cabinet is not in use. This helps keep the work zone interior clean. • The sash window should always be in the normal operating height at all times when the cabinet is in use.
- Page 27 However, if the use of a Bunsen burner is approved by a safety officer, it should be operated on the right side of the work zone. In Esco cabinets, the airflow sensor, when installed in the work zone, is mounted on the left side. Therefore, operating the burner on the right side would not affect the cabinet airflow monitoring system.
- Page 28 UV Lamps (If Present) Shortwave UV (UVC) is considered as germicidal and virucidal. The UV lamp that Esco provides has a large portion of the spectrum in the UVC range. Unlike many other types of decontamination agent, UV light doesn’t leave any residue.
- Page 29 Note: This is just a simplified cleaning and disinfection procedure. Choice of cleaning of disinfection procedures should be made through risk assessment. All facilities need to have adequate spill cleanup procedures. • There is no one disinfectant agent that works with all organisms. Therefore, user and the safety professionals should carry out risk assessment to ensure that appropriate disinfectant agent and validated decontamination procedures are used in decontaminating the cabinet.
- Page 30 7.1. Scheduled Maintenance Proper and timely maintenance is crucial for trouble free functioning of any device and your Esco cabinet is no exception to this rule. We strongly recommend that you follow the maintenance schedule suggested hereunder in order to obtain optimal performance from your Esco cabinet.
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