Focusrite Scarlett 2i2 Studio 4th Gen User Manual page 35

Mac
1. Open Cubase on your computer.
2. In the top menu bar click Studio > Studio Setup...
3. Change the ASIO Driver to Scarlett 2i2 4th Gen.
4. Click Switch.
5. Click OK.
6. Right-click in the MixConsole.
7. Click Add Track.
Scarlett 2i2 4th Gen Studio Pack User Guide
8. Configure the track type as Audio and set the Audio Input to the channel you're using
on your interface.
9. Click Add Track.
10. Click the Record Enable and Monitor buttons
enable the track for recording and so you can hear it using input monitoring
(on).
11. Click Transport Record
35
(off) on the Cubase channel to
in Cubase's transport to start recording.