Asus Rampage II GENE - Republic of Gamers Motherboard User Manual page 50

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In single VGA card mode, use first the PCIe 2.0 x16_1 slot for a PCI
Express x16 graphics card to get better performance.
In CrossFireX™ or SLI™ mode, use the PCIe 2.0 x16_1 and
PCIe 2.0 x16_2 (blue) slots for PCI Express x16 graphics cards to get
better performance.
We recommend that you provide sufficient power when running
CrossFireX™ or SLI™ mode. See page 2-37 for details. SLI™ mode. See page 2-37 for details.
Connect a chassis fan to the motherboard connector labeled CHA_FAN1/2
when using multiple graphics cards for better thermal environment. See
page 2-35 for details.
mode. See page 2-37 for details.
Chapter 2: Hardware information