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Bruker ICON System Manual

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ICON
System Manual
(Doc. No. T02985)

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Summary of Contents for Bruker ICON

  • Page 1 ICON  System Manual (Doc. No. T02985)
  • Page 2 © Copyright by Bruker BioSpin MRI GmbH All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form, or by any means without the prior consent of the publisher. Product names used are trademarks or registered trademarks of their respective holders.

  • Page 3: Table Of Contents

    Key Words and Symbols ..................23 Shut-Down ......................25 General Safety Information .................. 26 Mechanical Injury ....................27 Static and Electromagnetic Fields ................ 27 3.6.1 Static Magnetic Field .................... 28 3.6.2 Gradient Fields ..................... 30 3.6.3 Radio Frequency Fields ..................31 Icon System Manual T02985_02_03...
  • Page 4 4.9.2 Renversement du liquide de fantôme ..............57 4.9.3 Stockage des fantômes de mesure ..............58 4.9.4 Premiers secours en cas de contact avec un liquide de fantôme ....... 59 4.10 Sécurité de l´animal ..................... 60 Icon System Manual T02985_02_03...
  • Page 5 In- and Output Trigger ..................82 5.3.1 Input trigger ......................82 5.3.2 Output trigger ...................... 82 5.3.3 Trigger Connection Points ................... 83 Data Storage and Retrieval ................83 Quality Assurance..................84 Quality Phantoms ....................85 Placing the Phantoms ..................85 Icon System Manual T02985_02_03...
  • Page 6 Maintenance ....................93 Regular Checks....................93 8.1.1 Checks before Every Measurement..............93 8.1.2 Daily Checks ......................94 Cleaning ....................... 95 Contact ......................97 Appendix ......................99 List of Tables ......................99 List of Figures ..................... 100 Icon System Manual T02985_02_03...

  • Page 7: Introduction

    Introduction Introduction The System Manual is part of the multi-volume operating instructions for the ICON system. It provides information for the system operator. The operating instructions include the following manuals: Manual Document Numbers System Manual T02985 (this manual) ParaVision Software Documentation...
  • Page 8 Introduction Figure 1.1: ICON MRI system Icon System Manual T02985_02_03...

  • Page 9: Mri System Overview

    MRI System Overview MRI System Overview All components relevant for the usage of the ICON MRI system are described in the following sections. Figure 2.1: ICON MRI system overview Icon System Manual T02985_02_03...

  • Page 10: Magnet

    The ICON MRI system is equipped with a shielded permanent “always on” 1 Tesla (1 T) magnet: Figure 2.2: ICON permanent 1 T magnet. The main system switch for electronics (1) is located on the right side of the magnet. Animals or placed in the magnet through the front flange (2). The magnet has air-cooling fans on both sides (3, left fan not visible).

  • Page 11: Gradient And Shim Coils

    35 cm / 14 inches. Gradient and shim coils The ICON MRI magnet has a built-in set of three magnetic field gradient coils (x, y, z). The gradient coils are cooled by air-flow through the magnet. The air-cooling fans may be seen in Figure 2.2 (3).

  • Page 12: Electronic Cabinets

    They contain all components necessary for signal generation and detection, gradient and RF control. No user interaction is needed within these cabinets. Figure 2.3: The red marked cabinets contain all electronic components. No user interference is needed within these cabinets. Icon System Manual T02985_02_03...

  • Page 13: Anesthesia Cabinet

    The left-most cabinet is prepared for the use of an Isofluorane evaporator and an active carbon filter for scavenging (both options). Figure 2.4: The left-most cabinet is prepared for the usage of an anesthetic gas evaporator and an anesthetic scavenging system. Icon System Manual T02985_02_03...

  • Page 14: Animal Preparation Table

    A table for animal preparation is mounted on the anesthesia cabinet. It may accommodate the animal holder while not mounted in the magnet. Figure 2.5: The animal preparation table provides working space and accommodates the animal holder while not in use. Icon System Manual T02985_02_03...

  • Page 15: Animal Positioning System

    MRI System Overview Animal Positioning System The animal support for the ICON is modular and consists of the basic animal holder (see section 2.6.1) and exchangeable front pieces; the actual animal beds (see section 2.6.2). Every animal bed has a RF Coil included, supporting...
  • Page 16 Figure 2.6: Animal holder on its stand Figure 2.7: Left: Connection plate for the attachment of anesthesia gas, scavenging, warm water heating RF Coil. Right: Animal holder with mounted mouse body bed and mouse body RF Coil. Icon System Manual T02985_02_03...
  • Page 17 The center of the magnet is reached when the position mark of the animal holder is at the position marked as “0” position on the magnet front flange. Figure 2.9: The position and rotation of the animal holder with respect to the magnet center may be read from the magnet front flange. Icon System Manual T02985_02_03...

  • Page 18: Animal Beds

    A variety of dedicated animal beds is offered. Please note that not all of the beds are included in the standard delivery of an ICON MRI scanner. Dedicated RF Coils (see section 7.1) are part of the animal bed delivery.

  • Page 19: Rf Coils

    The ICON is equipped with tunable 1H single resonate transmit/receive RF Coils. The ICON MRI scanner is equipped with one 1H transmit/receive coil for mouse body applications per default. Apart from the standard RF Coil, a variety of different RF Coils can be obtained as options, i.e.:...

  • Page 20: Magnet Mounted Rf Coil

    2.7.2 Magnet mounted RF Coil As an alternative to the animal bed mounted RF Coils, the ICON can be equipped with an RF Coil mounted from the rear side of the instrument. For further information refer to section 5.2.3.2 and Technical Documentation/Components/ RF Coils/Rat Body 60 mm RF Coil.

  • Page 21: Keyboard

     Starting applications  Executing commands  Wheeler:  Context dependent scroll functionality  Replaces the middle mouse button  Drag & drop of data sets  Right mouse button:  Opening context dependent function menus Icon System Manual T02985_02_03...
  • Page 22 Icon System Manual T02985_02_03...

  • Page 23: Safety (English)

    Safety advice must be adhered in order to avoid dangerous situations for persons and property. There are also notices used in this manual. These notices highlight important information or warn the user of a potentially dangerous situation. Icon System Manual T02985_02_03...
  • Page 24 Indicates a hazardous situation which, if not avoided, could result in death or serious injury. CAUTION Indicates a hazardous situation which, if not avoided, may result in minor or moderate injury. NOTICE Hazard, which could result in property damage. Information and tips for efficient and trouble-free operation Icon System Manual T02985_02_03...

  • Page 25: Shut-Down

    The ON/OFF switch is installed near the magnet. It is recommended to check in regular intervals the free access to the unit. If a risk of electrical hazard occurs, the main power supply of the system must be switched off immediately using the ON/OFF switch. Figure 3.1: ON/OFF switch Icon System Manual T02985_02_03...

  • Page 26: General Safety Information

    Safety (English) General Safety Information The ICON product is subject to the safety demands given by the low voltage directive (LVD 2014/35/EEC). General electric safety is proven by the application of the safety requirements for electrical equipment for measurement, control and laboratory use of the EN 61010-1 and EN 61010-2-081.

  • Page 27: Static And Electromagnetic Fields

    Ensure that occupational standards are taken into account while preparing experimental setups or while scanning. 3.6.1 Static Magnetic Field The static magnetic field is generated by a shielded 1 Tesla permanent magnet to minimize the surrounding fringe field. The static magnetic field is highly homogeneous Icon System Manual T02985_02_03...

  • Page 28: Static Magnetic Field

    The magnet may not be switched off. Do not try to remove accidentally attracted magnetic items from inside the magnet. Contact your local Bruker service instead. CAUTION Icon System Manual T02985_02_03...
  • Page 29 The magnetic field may  erase magnetic data media (e.g. magnetic disks, magnetic tapes, diskettes, credit cards)  destroy mechanically sensitive components (e.g. watches, cameras)  Do not bring any of these items into the MRI magnet. Icon System Manual T02985_02_03...

  • Page 30: Gradient Fields

    Depending on the animal setup and the remaining air circulation, a lethal heating of the animal can occur.  Monitor and control the body temperature of the animal under investigation. Icon System Manual T02985_02_03...

  • Page 31: Radio Frequency Fields

    Forming body loops with e.g. the extremities may induce strong currents in the body tissue and lead to local burn injuries.  Avoid forming loops with body parts, e.g. do not put the front paws together.  Twist ECG cables closely to minimize inductions in the ECG. Icon System Manual T02985_02_03...
  • Page 32  To avoid such situations, the system must be used under the normal operating conditions as defined in the System Owner Manual. In general, the RF Coils must be entered in the magnet before using them. Icon System Manual T02985_02_03...

  • Page 33: Rf Coils And Accessories

    Safety (English) RF Coils and Accessories Under normal operation conditions no risk to the operator arises from the usage of Bruker tested RF Coils and accessories. Nevertheless, the following safety aspects need to be considered. WARNING Risk of injury or death.

  • Page 34: Medical Gases

    Carry out appropriate compliance with the regulations;  Allow for sufficient fresh air and use extraction system for anesthetic gases;  Make sure, that the scavenging system is turned on (if present). Icon System Manual T02985_02_03...
  • Page 35 Risk of personal injury. Visually inspect all tubes and connections of the anesthesia system for leaks. In particular, pay attention to wheezing noises in the pressurized system arising from possible leaks.  Immediately replace all defective or leaking parts. Icon System Manual T02985_02_03...

  • Page 36: Phantom Fluids

    Handling of Measurement Phantoms Always handle measurement phantoms with great care. Under normal operating conditions, no risk to the operator arises from the usage of Bruker phantoms. Although all phantoms were designed under the aspect of harmless chemical composition, a small residual risk to the operator cannot be avoided especially with leaking or broken phantoms.

  • Page 37: Phantom Fluid Spills

     Collect the fluid in a plastic container or equivalent and label it accordingly.  Remove any pollution from spilled phantoms inside the MRI system before using it again.  Clean your hands thoroughly using soap and water and change contaminated clothing. Icon System Manual T02985_02_03...

  • Page 38: Storage Of Measurement Phantoms

    Safety (English) CAUTION Phantom disposal as special waste.  Label the container accordingly.  Hire an authorized special waste company for disposal.  If you have additional questions, contact Bruker Service. 3.9.3 Storage of Measurement Phantoms CAUTION Risk of fire.

  • Page 39: First Aid In Case Of Contact With Phantom Fluid

    Immediately wash the skin using soap and water. Eye contamination:  It is recommended to consult an ophthalmologist. Swallowing:  Rinse mouth with water and drink plenty of water. Inhalation:  Leave the building immediately to get fresh air. Icon System Manual T02985_02_03...

  • Page 40: Animal Safety

    Risk of peripheral nerve stimulation of animals. Excessive gradient usage may lead to peripheral nerve stimulation during measurements.  Permanently supervise the animal’s health status during MRI measurements. Should the situation arise stop the measurement immediately. Icon System Manual T02985_02_03...
  • Page 41 Safety (English) Icon System Manual T02985_02_03...
  • Page 42 Safety (English) Icon System Manual T02985_02_03...

  • Page 43: Sécurité (Français)

    Les conseils de sécurité doivent être collés en évidence de manière à éviter des situations dangereuses pour les personnes ou les biens. Des remarques sont aussi présentes dans ce manuel. Ces remarques mettent en évidence des informations importantes ou des mises en garde pour les utilisateurs. Icon System Manual T02985_02_03...
  • Page 44 Indique une situation de danger qui, si elle n´est pas évité, peut comporter un risque de blessure mineur ou modérée REMARQUE Danger, qui peut résulter dans un dommage matériel Information et conseils pour une utilisation efficace et sans problèmes Icon System Manual T02985_02_03...

  • Page 45: Arrêt

    L´interrupteur d´arrêt est installé près de l´aimant. Il est recommandé de vérifier régulièrement que l´accès á cet interrupteur n´est pas obstrué. En cas de risque électrique, l´alimentation électrique principale du système doit être coupée immédiatement en utilisant l´interrupteur d´arrêt. Figure 3.1: Interrupteur d´arrêt Icon System Manual T02985_02_03...

  • Page 46: Information De Sécurité Générale

    Sécurité (Français) Information de sécurité générale Le produit ICON est soumis aux exigences de sécurité mentionnées dans la directive concernant les basses tensions (LVD 2014/35/EEC). La sécurité électrique générale est garantie par l´application des exigences de sécurité pour les équipements électriques à...

  • Page 47: Blessure Mécanique

    Les champs à radiofréquence: les bobines RF entraînées par des amplificateurs électriques RF produisent des champs électromagnétiques pulsés à haute fréquence. Normes professionnelles Assurez-vous que les normes professionnelles sont prises en compte pendant la préparation de l'expérimentation ou du scanner. Icon System Manual T02985_02_03...

  • Page 48: Champ Magnétique Statique

    été attirés par l'aimant pourraient ne plus pouvoir être retirés, créant des dommages importants à l'aimant. L’aimant peut ne pas être éteint. N’essayez pas de retirer les objets magnétiques accidentellement attirés dans l’aimant. Contactez votre service d’entretien local Bruker. Icon System Manual T02985_02_03...
  • Page 49 Le champ magnétique peut  Effacer les supports de données magnétiques (ex. disques magnétiques, cassettes magnétiques, disquettes, cartes de crédit).  Détruire les composants mécaniquement sensibles (ex. les montres, appareils photo).  N’apportez aucun de ces articles dans l’IRM. Icon System Manual T02985_02_03...

  • Page 50: Champs À Gradient

    élevées sur la surface intérieure de la bobine de gradient. Selon l'installation de l'animal et la circulation d'air restante, un réchauffement fatal de l'animal peut se produire.  Contrôlez la température corporelle de l’animal étudié. Icon System Manual T02985_02_03...

  • Page 51: Les Champs À Radiofréquence

    élevés dans les tissus corporels et provoquer des brûlures locales.  Evitez de former des boucles avec les parties du corps, ex. ne placez pas les pattes avant, ensemble.  Enroulez les câbles ECG pour réduire l'induction dans l'ECG. Icon System Manual T02985_02_03...

  • Page 52: Bobines Rf Et Accessoires

    Bobines RF et accessoires Dans des conditions normales d’utilisation, aucun risque pour l’utilisateur n’est provoqué par l’utilisation des bobines RF Bruker testées et des accessoires. Néanmoins, les aspects sécuritaires suivants doivent être pris en compte. AVERTISSEMENT Risque de blessure ou de décès.
  • Page 53 ≤ 40 °C avant de l’utiliser. Toute utilisation des bobines RF et accessoires qui ne sont pas testés et validés par Bruker pour la compatibilité avec le système MR enfreint la déclaration de conformité et comprend un risque potentiel.
  • Page 54  Le nettoyage humide des bobines RF doit être évité autant que possible. Tout liquide dans les bobines RF doit être totalement évaporé avant d’utiliser la bobine RF.  N’utilisez pas une température (≤ 40 °C) ou une ventilation excessive pour sécher les bobines RF après le nettoyage. Icon System Manual T02985_02_03...

  • Page 55: Gaz Médicaux

    Inspectez visuellement tous les tubes et connexions du système d’anesthésie pour identifier toute fuite. Faites particulièrement attention aux sifflements dans le système de pressurisation qui pourraient provenir de fuites.  Remplacez immédiatement toute pièce défectueuse ou fuyante. Icon System Manual T02985_02_03...

  • Page 56: Liquides De Fantôme

    Bruker. Même si tous les fantômes sont conçus selon une composition chimique sans danger, un petit risque résiduel pour l’opérateur ne peut pas être évité, en particulier en ce qui concerne les fantômes cassés et fuyants.

  • Page 57: Renversement Du Liquide De Fantôme

     Collectez le liquide dans un container en plastique ou un équivalent et étiquetez-le.  Supprimez toute pollution provenant des fantômes renversés dans l'IRM avant de l’utiliser de nouveau.  Nettoyez vos mains minutieusement avec de l’eau et du savon et changez vos vêtements contaminés. Icon System Manual T02985_02_03...

  • Page 58: Stockage Des Fantômes De Mesure

    Eliminez le fantôme en tant que déchet spécial.  Etiquetez le container.  Faites appel à une entreprise officielle de traitement des déchets spéciaux pour effectuer le rejet.  Si vous avez de plus amples questions, contactez Bruker Service. 4.9.3 Stockage des fantômes de mesure ATTENTION Risque d’incendie.

  • Page 59: Premiers Secours En Cas De Contact Avec Un Liquide De Fantôme

    Lavez immédiatement la peau avec de l’eau et du savon. Contamination des yeux :  Il est recommandé de consulter un ophtalmologue. Absorption :  Rincez la bouche à l'eau et buvez abondamment. Inhalation :  Quittez immédiatement le bâtiment et respirez à l’air libre. Icon System Manual T02985_02_03...

  • Page 60: Sécurité De L´animal

     Afin de réduire la température ambiante, réduire la température de l´eau de l´unité de refroidissement de l´animal ou agir sur l´air conditionné dans la pièce. Vérifier que le flux d´air généré par les ventilateurs des gradients n´est pas obstrué. Icon System Manual T02985_02_03...
  • Page 61  Controller de manière continue les paramètres physiologiques de l´animal lors de l´ expérience. Dans le cas où la situation décrite ci-dessus se produit, stopper immédiatement la mesure en cours. Icon System Manual T02985_02_03...
  • Page 62 Icon System Manual T02985_02_01...

  • Page 63: Mri System Operation

    (except the power line distributor serving the power switches) Start-Up The green LED is flashing for approximately 40 seconds during spectrometer start-up. The spectrometer is ready for use. Icon System Manual T02985_03...

  • Page 64: Switching On

    The scanner must be in the “ON” state, indicated by the lit green LED. To power down, press the power off button. This will immediately set the scanner into “OFF” state. The “OFF” state is indicated by the lit red LED. Icon System Manual T02985_02_03...

  • Page 65: Prepare And Run Scans

    Prepare and Run Scans 5.2.1 Introduction The animal support for the ICON is modular and consists of the basic animal holder (see section 2.6.1) and exchangeable front pieces; the actual animal beds including dedicated RF Coils (see section 2.6.2). Every animal bed supports a dedicated application (i.e.

  • Page 66: Basic Workflow

    3. Position the setup in the magnet. Preparation Position animal/ Position setup in the Mount animal bed sample on the bed magnet Figure 5.1: Prepare and run scans: Preparation The generalized ParaVision workflow includes the four steps shown below: Icon System Manual T02985_02_03...

  • Page 67: Mounting The Animal Beds To The Basic Holder

    Two warm water tubes (6) (in-/outlet) for animal warming Figure 5.2: Mouse body animal bed (1) Mouse animal bed; (2) Anesthesia mask; (3) Tooth bar; (4) Anesthesia connection to tooth bar; (5) Scavenging; (6) Warm water tubes (in- and outlet) for animal warming Icon System Manual T02985_02_03...
  • Page 68 Coil on the coil fixation rod of the basic holder. Figure 5.3: Mouse body RF Coil. (1) Coil housing; (2) Tuning rod connector; (3) RF connection; (4) Hole for inserting the coil shifting rod; (5) Coil fixation on the fixation rod Icon System Manual T02985_02_03...
  • Page 69 Figure 5.5: Left: Notch (1) on the bottom side of the animal bed. Right: Front part of the basic animal holder. (2) Rail for holding the animal bed notch (1); (3) Fixation for animal bed (lever from below is not visible); (4) Tuning rod; (5) Coil fixation rod Icon System Manual T02985_02_03...
  • Page 70 For body RF Coils this should be done after placing the animal on the animal bed since the coil is not integral part of the animal bed. Please refer to section 5.2.4 on page 69.  Respiratory sensor (option, not shown)  ECG electrodes (option, not shown) Icon System Manual T02985_02_03...

  • Page 71: Connecting Rf Coils

    (1) located on the bottom side of the magnet, as shown in Figure 5.8. The other connections are not in use (not connected). Figure 5.8: RF Coil connection located on the magnet’s bottom side Icon System Manual T02985_02_03...
  • Page 72 When using magnet mounted RF Coils connect the BNC cable (2) as described in section 5.2.4.1 with the BNC connector as shown in Figure 5.9. Figure 5.9: RF Coil connection located on the rear side (1) Fixation screws; (2) BNC cable Icon System Manual T02985_02_03...

  • Page 73: Positioning

    Carry out appropriate compliance with the regulations;  allow for sufficient fresh air and use extraction system for anesthetic gases;  make sure that the scavenging system is turned on (if present). Icon System Manual T02985_02_03...
  • Page 74 (2). Then the animal is pulled into the respiration mask (3). The tooth bar is fixed with a knurled screw (not shown). Place all necessary life and health monitoring sensors on the animal and connect them. Icon System Manual T02985_02_03...
  • Page 75 (1) is aligned with the hole (2) on the body RF Coil, as shown in Figure 5.12. Figure 5.12: (1) Magnet Center marking on the animal bed. (2) The hole in the body RF Coil was aligned with the Magnet Center marking. Icon System Manual T02985_02_03...
  • Page 76 Figure 5.14: Fixate the Basic Animal Holder in the magnet with the knurled screw (1). Two scales, one for horizontal shifts (2, with 2-mm division), and one for rotation (3, with 3-degree division) facilitate positioning. The Magnet Center Position is reached when both scales show zero. Icon System Manual T02985_02_03...

  • Page 77: Tuning Of Rf Coils

    TH RF Coil is tuned (on-resonant), but miss-matched => change the matching of the coil Please check the coil-specific user manual for dedicated procedures that are not described in this manual. Icon System Manual T02985_02_03...
  • Page 78 2. Start the tune/match from ParaVision (see corresponding chapter in ParaVision software manual). 3. Adjust and optimize the tune and match condition by turning the tune and match knobs of the RF Coil (labeled T or M). 4. Stop the tune/match on the RF interface display. Icon System Manual T02985_02_03...

  • Page 79: Scanning

    Tune RF coil (only Acquire Localizer Localizer scan once per patient) scan New Scan & Adjust Geometry Acquire scan load protocol Study finished? Patient finished? Session finished Figure 5.15: Detailed standard workflow for routine system operation Icon System Manual T02985_02_03...
  • Page 80 5.2.7.2 Protocol Adaption ICON offers more than one hundred in vivo optimized protocols for mice and rats for various applications. For routine work, only the slice position and orientation should be adapted on a per-scan basis. Other parameters should be kept untouched for the less experienced user.
  • Page 81 For pure anatomical imaging, the following 3D FLASH isotropic resolutions may be reached: Mouse head: ca. (175 µm)³ within ca. 15 minutes ca. (140 µm)³ within ca. 60 minutes Rat head: ca. (240 µm)³ within ca. 15 minutes ca. (190 µm)³ within ca. 60 minutes Icon System Manual T02985_02_03...

  • Page 82: In- And Output Trigger

    MRI System Operation In- and Output Trigger The ICON AVANCE III MRI electronics provides one programmable input trigger and one programmable TTL output signal. The trigger connector has a quick latch QLA type connector, including a QLA/BNC adapter. 5.3.1 Input trigger Input trigger signals are used for synchronizing the scanner with external signals or events, e.g.

  • Page 83: Trigger Connection Points

    “ECG STAMP”. Data Storage and Retrieval Data storage and retrieval is supported by the ParaVision Data Manager software. Please refer to the ParaVision Operation Manual for a detailed description of the Data Manager and supported storage devices. Icon System Manual T02985_02_03...

  • Page 84: Quality Assurance

    Repeating measurements and recording them over time will enable the operator to establish a site specific value for reproducibility and performance. Quality Assurance of most Bruker RF Coils is based on the protocol QA SNR located in the Scan Programs & Protocols tree “AnyObjects”, “AnyRegions”, “QualityAssurance”.

  • Page 85: Quality Phantoms

    To achieve this, all animal beds except the mouse body bed have dedicated phantom holders. An example for the rat load phantom holder on the rat body animal bed is shown in Figure 6.2. Icon System Manual T02985_02_03...
  • Page 86 MRI System Operation Figure 6.2: Phantom holder for the rat load phantom on the rat body animal bed. Icon System Manual T02985_02_03...
  • Page 87 For details please refer to section 5.2.5.2 on page 73. A final setup for the mouse body animal bed is shown in Figure 6.5. When finished, insert the setup into the magnet. Icon System Manual T02985_02_03...
  • Page 88 MRI System Operation Figure 6.5: Final phantom setup for the mouse body animal bed. Icon System Manual T02985_02_03...

  • Page 89: Accessories

    Accessories The following chapter gives an overview of the typical accessories optionally available for your MRI system. In addition to these typical accessories, Bruker BioSpin MRI provides for many applications special accessories. Please contact your local Bruker representative for details.
  • Page 90 300 g body weight, solenoid coil design, transmit/receive capabilities, inner diameter: 35 mm, length: 40 mm, integrated animal bed. Table 7.1: Available animal beds and coils For details on the RF Coils and animal beds please refer to the Technical Documentation. Icon System Manual T02985_02_03...

  • Page 91: Animal Life Monitoring Unit (Mtlimo01)

    5.3 on pages 80 ff. For details on the animal monitoring and gating system, see accessories operating instructions. Figure 7.1: MR compatible small animal monitoring and gating system (option) Icon System Manual T02985_02_03...

  • Page 92: Animal Body Conditioning Unit (Mt0125)

    Accessories Animal Body Conditioning Unit (MT0125) An animal body warming unit is available (option). All ICON animal beds have an integrated warm water beds and may be connected to this warming unit. For details, see accessories operating instructions. Icon System Manual T02985_02_03...

  • Page 93: Maintenance

    The gradient coils may overheat and result in fire or personal injury if the cooling air flow is constrained. Visually inspect both (left and right) gradient cooling fans at the magnet before starting the measurement.  Make sure that nothing covers the fan openings. Icon System Manual T02985_02_03...

  • Page 94: Daily Checks

    Check daily if the maximum capacity of the scavenging filter (if present) is exceeded, according to the instructions of the manufacturer of the filter.  Replace the filter early enough to prevent the egression of narcotic gases (medical gases). Icon System Manual T02985_02_03...

  • Page 95: Cleaning

    Dampen a soft cloth with water or a diluted household cleaner solution  Carefully wipe the plugs and connectors with the cloth. Do not touch the contacts  Do not use hard or sharp objects (e.g. knives or tweezers) Icon System Manual T02985_02_03...
  • Page 96 Icon System Manual T02985_02_03...

  • Page 97: Contact

    Phone: +49 721-5161-6621 E-mail: mri-application-support@bruker.com Software Hotline Phone: +49 721-5161-6588 E-mail: mri-software-support@bruker.com Please refer to the Model No., Serial No. and Internal Order No. (see System Owner Manual) in all correspondence regarding the MR system or components thereof. Icon System Manual T02985_02_03...
  • Page 98 Icon System Manual T02985_02_03...

  • Page 99: Appendix

    Appendix Appendix List of Tables Table 7.1: Available animal beds and coils ............... 88 Icon System Manual T02985_02_03...

  • Page 100: List Of Figures

    MRI system ..................8 Figure 2.1: ICON MRI system overview ................9 Figure 2.2: ICON permanent 1 T magnet. The main system switch for electronics (1) is located on the right side of the magnet. Animals or placed in the magnet through the front flange (2).
  • Page 101 Figure 5.16: Left: Power mains connection point (1), console power connection (2) and trigger connection points (3) inside the anesthesia cabinet. Right: Enlargement of the trigger connection points. The input trigger connection is labeled “ECG TRIG IN”; the output trigger connection is labeled “ECG STAMP”...................... 81 Icon System Manual T02985_02_03...
  • Page 102 (3) rests in the deepening of the phantom holder....... 85 Figure 6.5: Final phantom setup for the mouse body animal bed........86 Figure 7.1: MR compatible small animal monitoring and gating system (option) ....89 Icon System Manual T02985_02_03...
  • Page 103 Icon System Manual T02985_02_03...
  • Page 104 Icon System Manual T02985_02_03...
  • Page 105 Revision History List Index: Date: Alteration Type: First version of a new document, all pages have the status: 15.04.2011 "Rev: 01" Document release after review. Status set to: “Rev.1.0” 23.12.2011 23.06.2016 Update ParaVision 6 and new 60 mm RF Coil for rat body...

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