logos biosystems X-CLARITY TISSUE CLEARING SYSTEM II Installation Manual

X-CLARITY
This Installation Guide provides instructions for installing the X-CLARITY™ Tissue Clearing System II. For detailed instructions, refer to the user manual in the supplied USB drive.
COMPONENTS
Buffer
Reservoir
Tray
ETC Chamber ETC Control Tower
Peristaltic Silicone
Pump Tube Tube
Container Holder Tissue Containers (20)
© 2020 Aligned Genetics, Inc. All Rights Reserved.
Rev. 2
TISSUE CLEARING SYSTEM II
™
INSTALLATION GUIDE
Multi-cable
Power Cord
USB Drive, 16 GB
Snap-lock
Connector Tube
*Assembly required
Electrophoretic Tissue
Clearing Solution (12 L)
INTENDED USE
The X-CLARITY™ Tissue Clearing System II is a set of electrical laboratory instruments for scientific research
use only. It is not a medical, therapeutic, or in vitro diagnostics device.
GENERAL GUIDELINES
To ensure proper ventilation and prevent overheating, leave at least 5 cm (2 in) around the X-CLARITY
1.
ETC Control Tower. Do not block the air vents around the unit.
Make sure samples are prepared properly prior to clearing. Insufficient hydrogel polymerization can
2.
lead to inadequate clearing. Polymerization must be performed in a precisely controlled, oxygen-free
environment with fresh ingredients. Use the X-CLARITY
Polymerization System for optimal results.
Use fresh Electrophoretic Tissue Clearing Solution with each run. Reused clearing solution may have
3.
lowered buffering capacity, which reduces clearing efficiency. After prolonged use, the extracted lipids
in solution may undergo electrolysis and turn tissue samples yellow.
Use the recommended volume of Electrophoretic Tissue Clearing Solution in the provided X-CLARITY™
4.
Buffer Reservoir. Do not use organic solvents other than the Electrophoretic Tissue Clearing Solution
from Logos Biosystems. Different solvents may cause permanent and irreparable damage.
When clearing a tissue type for the first time or using a different sample holder, check the sample every
5.
two hours to keep tabs on its progression.
Do not try to achieve absolute transparency. Placing cleared samples in an RI matching solution
6.
(X-CLARITY ™ Mounting Solution, C13101) will achieve maximum transparency.
Operate the system in the conditions described below.
7.
Operating Power
Frequency
Installation Site
Operating Temperature
Maximum Relative Humidity
Altitude
Pollution Degree
USB Port
™ Hydrogel Solution Kit and X-CLARITY ™
100 ‒ 240 VAC, 2 A
50/60 Hz
Indoor use only
10 ‒ 30°C
20 ‒ 70%
≤ 2,000 m
2
5 VDC, 500 mA
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™