Thermo Scientific Multidrop Pico 8 Operating Manual

Thermo Scientific Multidrop Pico 8 Operating Manual

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Thermo Scientific™
Multidrop™ Pico 8 Digital Dispenser
Operating Manual
Cat. no. 1509040 Rev. 01

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Summary of Contents for Thermo Scientific Multidrop Pico 8

  • Page 1 Thermo Scientific™ Multidrop™ Pico 8 Digital Dispenser Operating Manual Cat. no. 1509040 Rev. 01...
  • Page 2 Copyright  2019 Thermo Fisher Scientific Inc. All rights reserved. Microsoft and Windows are registered trademarks of the Microsoft group of companies. All other trademarks and registered trademarks are the property of their respective holders. Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in product operation.
  • Page 3: About This User Manual

    Note Marks a tip, important information that is useful in the optimum operation of the system, or an item of interest. Tip Gives a helpful hint for getting the most out of the software functionality. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 5: Table Of Contents

    Loading a plate ................18 Cassette prompt and loading a cassette ..........19 Loading a cassette ................20 Load fluid prompt ................20 Locking dispensehead cassettes ............22 Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 6 Load and validate ................32 Fluid and Dispense ................. 32 Adjust ..................... 32 A1 realignment................33 Preventive maintenance completion form ........34 Chapter 7 Legal and regulatory notices ..............35 Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 7: Introduction To The Multidrop Pico Dispenser

    It increases research productivity by reliable results provided at higher speed using flexible and intuitive experiment design software Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 8: Advantages Of The Multidrop Pico Dispenser

    Avoid carry-over and contamination with single use, non-contact dispensing supplies. The Multidrop Pico dispenser is applicable to many low- volume assay procedures with one system. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 9: Chapter 2 Safety

    A Class 1 laser is used in the Multidrop Pico dispenser to determine the height of the destination plate. This Class 1 Laser follows the requirements of Laser Notice No. 50 of the FDA (CDRH), Accession Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 10: Electrical Safety

    Multidrop Pico dispenser for servicing.Recommended cleaning and decontamination procedures are described in the Cleaning the Multidrop Pico dispenser section. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 11: Safe Disposal Of Cassettes And Pipette Tips

    Pico dispenser computer. Additional Contact the Service Help Desk for additional assistance. The contact Service and information can be found in the Multidrop Pico dispenser assistance Support document. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 12: Chapter 3 System Specifications

    Temperature: 20°C - 30°C laboratory conditions (68 - 86°F) operating • Humidity: 30% - 80% RH conditions Shipping and • Temperature: 10°C - 32°C (50°F – 90°F) storage • Humidity: 20% - 80% RH conditions Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 13: Compatible Well Plates

    Meet ANSI specifications for footprint dimensions and well locations, if applicable. • Between 6 mm and 47 mm in height. Additional Software User Guide See the Multidrop Pico dispenser for more system specifications. specifications Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 14: Understanding The Multidrop Pico Dispenser

    Do NOT plug the power supply into the incorrect voltage. If the labeled voltage on the power supply does not match your standard outlet, contact the Service Help Desk. The contact Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 15 Use the USB cable that came with the Multidrop Pico dispenser to connect the computer to the Multidrop Pico dispenser. The USB port is on the back of the Multidrop Pico dispenser. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 16: Chapter 5 Running A Protocol

    The upper portion shows a “status” display area, indicating Waiting on Operator for plate and fluid preparation. There is also a progress circle that lets you know how far along the protocol run is. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense...
  • Page 17: Pause/Abort

    Nevertheless, you can move your cursor over the wells on the monitor screen to see the well summary information. Once dispensing begins the Well plate grid shows the dispense progress as fluids are dispensed into the wells. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 18: Plate Prompt And Loading A Plate

    Make sure the plate is completely level and down on the destination plate holder. • Ensure that the A1 well position (upper-left-most well in the grid) is at the top-left corner of the destination plate holder. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 19: Cassette Prompt And Loading A Cassette

    Click Loaded (or F6) to proceed. Cassette prompt When a cassette is required, a Cassette Load prompt is displayed, indicating the type of cassette required. and loading a cassette Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 20: Loading A Cassette

    The prompt has an entry for fluids used in the protocol, color-coded prompt and number-coded (in concert with the numbered cassette reservoirs) with stock concentration and the required load volume. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 21 Filled for each fluid, or you can fill all the reservoirs prior to initiating dispensing by clicking on All Filled. Note For aqueous fluids, it is recommended that fluids not be prefilled due to evaporation. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 22: Locking Dispensehead Cassettes

    To modify load volume, move the cursor over the volume on the s and click when highlighted. A popup box allows the dispensehead volume to be modified. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 23: Loading The Fluids

    LARGEST load volume of the set of dispenseheads you are loading, which is noted as the Maximum load volume in the bottom right corner of the Fluid load prompt. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 24 Note Make sure to load the fluid into the opening on top of the dispensehead by placing the pipette tip in the opening and expelling the fluid as shown above. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 25 E1-ClipTip Single LTR0001, LTR0004 channel, 2-125 μL 4670030BT E1-ClipTip Single LTR0002, LTR0003 Channel, 10-300 μL 4672030BT E1-ClipTip Equalizer LTR0004 384, 8-ch 1-30 μL E1-ClipTip electronic pipette compatibility chart. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 26: Fluid Dispensing

    Cassette As additional cassettes are needed, dispensing will pause and, you will be prompted to load a new cassette and the fluids needed for that changes cassette. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 27: Preventative Maintenance Procedures

    Clean the Multidrop Pico dispenser according to the cleaning procedures described in the Cleaning the Multidrop Pico dispenser section below. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 28: Cleaning The Multidrop Pico Dispenser

    All the outside surfaces of the Multidrop Pico dispenser The pogo mechanism housing, excluding the pogo pin • area (circled in red, below). Do not spray the pogo pins with cleaning fluid. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 29: Pogo Pin Inspection

    Manually move the well plate to the back-right corner. Using gloves, gently extend the pogo block out of the instrument and gently pull it down. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 30: Pogo Pin Cleaning

    Texwipe, saturated with isopropyl cleaning alcohol. After wiping the pogo pins, push the pogo block back into the instrument. Allow the isopropyl alcohol to dry prior to next use. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 31: A1 Alignment Check

    Press Start Guided Alignment to be guided through the verification and (optional) alignment process. To skip guided alignment, select the Manual Adjustment tab to adjust the dispense location. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 32: Load And Validate

    After loading the fluid and clicking Next, fluid will be dispensed to the centers of the 4 corner wells. Adjust After dispensing, the plate will be moved to a position where it can be examined or removed for closer examination. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 33: A1 Realignment

    Remember to clean the plate cover or seal before re-dispensing. The usual procedure is to adjust and re-dispense to verify the adjustment until alignment is good. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 34: Preventive Maintenance Completion Form

    A1 Alignment Check   A1 Realignment The undersigned confirms that these Preventive Maintenance procedures have been performed: ______________________ _________________________ PM(s) Performed By Email ______________________ __________________________ Signature Date Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 35: Legal And Regulatory Notices

    0.1 weight % and 0.01 weight % for cadmium, except where allowed pursuant to the exemptions set in Schedule 2 of the Rule. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 36 úřadů místní samosprávy, od společnosti provádějící svoz a likvidaci domovního odpadu nebo v obchodě, kde jste produkt zakoupili. Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 37 Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 38 Kommunala myndigheter, sophanteringsföretag eller butiken där varan köptes kan ge mer information om var du lämnar kasserade produkter för återvinning. 欧盟国家/地区用户在私人住宅中对废旧设备的处理 产品或包装上包括此标志表示此产品不得作为住宅垃圾来处理。而且您有 责任将废旧设备送到指定的废旧电力电子 设备回收点,通过这种方式来 处理废旧设备。废旧设备的分类收集与回收有助于节约自然资源,保证以 有利于人类 健康和环保的方式回收废旧设备。有关废旧设备回收的详细 信息,请与当地市政机关、家庭垃圾处理站或购买产品 的商店联系。 Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 39 外壳面板 激光检测仪 媒体 (CD) 电机组件 印刷电路组 件 / 电气元件 电源适配器/ 电源 传感器 静电消除棒 本表格依据SJ/T 11364 的规定编制。 O:表示该有害物质在该部件所有均质材料中的含量均在GB/T 26572 规定的限量要求以下。 X:表示该有害物质至少在该部件的某一均质材料中的含量超出GB/T 26572 规定的限量要求。 此表中所有名称中含 “X” 的部件均符合欧盟 RoHS 立法。 注:环保使用期限的参考标识取决于产品正常工作的温度和湿度等条件 Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 40 (Cr(VI)) (PBB) (PBDE) Cable / Wiring Chassis Consumable Outer Cover Panel Laser Detector Media (CD) Motor Assembly PCA / Electrical Component Power Adapter / Supply Sensor Static Elimination Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual Thermo Fisher Scientific...
  • Page 41 European Union’s RoHS Legislation. Note: The referenced Environmental Protection Use Period Marking was determined according to normal operating use conditions of the product such as temperature and humidity. Thermo Fisher Scientific Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual...
  • Page 42 ThermoFisher Scientific Thermo Scientific Dispenser Operating Manual [Subject]...

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