Introduction To The Multidrop Pico Dispenser; How The Multidrop Pico Dispenser Works - Thermo Scientific Multidrop Pico 8 Operating Manual

Multidrop Pico
dispenser works
Thermo Fisher Scientific
Chapter 1
Introduction to the Multidrop Pico
dispenser
How the
The Multidrop Pico dispenser provides fast and reliable dispensing
performance across a large dynamic range, eliminating slow, wasteful,
and error-prone manual serial dilutions and enabling assay
miniaturization through low-volume assay component addition.
The Multidrop Pico dispenser provides fast and reliable dispensing
across a wide range of life science applications:
• Dose-response curves for small molecule and biomolecule-based
• Drug-drug synergy experiments for drug discovery
• Low-volume assay component dispensing of a wide range of
• Complex enzyme kinetic studies
• DMPK standards
Using single-use cassettes to help avoid the possibility of cross-
contamination, the Multidrop Pico dispenser offers non-contact digital
dispensing in the picoliter to microliter range. It combines walk-up
convenience, ready-to-run performance and flexible, intuitive
experiment design software to increase research productivity, reliability
of results, and speed of life science research.
Even the most complex experimental plate layouts, such as drug-drug
interaction (synergy) studies, can be made simple. Titrating one drug
down the plate while another is titrated orthogonally across the plate
enables two or more drug doses to be independently generated in every
well. In addition, plate layouts can be randomized to reduce the impact
of edge effects, increasing the integrity of the experimental data. The
Multidrop Pico dispenser offers a convenient solution to address the
most challenging experiments.
The Multidrop Pico dispenser offers non-contact digital dispensing
utilizing single-use cassettes to avoid contamination in picoliter to
microliter range. It increases research productivity by reliable results
provided at higher speed using flexible and intuitive experiment design
software
drug discovery research
fluids into microplates
Thermo Scientific™ Multidrop™ Pico 8 Digital Dispense Operating Manual 7