Millipore Milli-Q User Manual

Integral water purification system

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User manual (101 pages)

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Richard van Breemen

June 9, 2025

What is the fix for error code #3 on my Milli-Q Biocel zmqs60f01? The manual simply states to unplug the unit and try again, but that did not fix the problem.

Summary of Contents for Millipore Milli-Q

Page 1: Table Of Contents
Description of Manager Menu ...................52 Ready Mode ...........................56 Overview ..........................56 Ready Mode - General information ...................57 Description of Ready Menu ....................58 Using the Milli-Q System......................61 Overview ..........................61 Dispensing water ........................62 Main Keypad, Display and LEDs ..................63 Q-POD Keypad and Display ....................65...
Page 2 Maintenance..........................66 Overview ..........................66 Maintenance Schedule......................67 Replacing the Progard Pack ....................68 Replacing the Quantum Cartridge..................70 Replacing a POD Pak......................73 Cleaning the A10 TOC Monitor..................76 Sanitising or cleaning the RO Cartridge ................78 Cleaning the Inlet Strainer....................79 Replacing the Tank Vent Filter ..................80 Alarms and Alerts........................81 Overview ..........................81 Alert messages........................82...
Page 3: Introduction
Some of the more important topics in this chapter are: • Safety Information • Where to find information Contents This chapter contains the following topics: Topic See Page About this User Manual About Millipore Legal Information Safety Information Where to find information...
Page 4: About This User Manual
If this User Manual is not the correct one for your Water Purification System, then please contact Millipore. Terminology The term “Milli-Q Integral Water Purification System” is replaced by the term “Milli-Q System” for the remainder of this User Manual unless otherwise noted.
Page 5: About Millipore
See the business card(s) on the inside cover of the User Manual binder. Internet The Millipore Internet site address can be used to submit a question to Millipore via electronic mail. The Millipore Internet site can be used to find addresses, telephone/fax numbers and other information.
Page 6: Legal Information
Millipore Corporation assumes no responsibility for any errors that might appear in this document. This manual is believed to be complete and accurate at the time of publication. In no event shall Millipore Corporation be liable for incidental or consequential damages in connection with or arising from the use of this manual.
Page 7 Legal Information, Continued Trademarks Millipore, A10, Elix, Q-Gard, Milli-Q, Millipak and Milli-RO are registered trademarks of Millipore Corporation. BioPak, Quantum, Milli-RX, RiOs and Q-POD are trademarks of Millipore Corporation. All other trademarks are trademarks of their respective manufacturers. © 2007 MILLIPORE CORPORATION. PRINTED IN FRANCE. ALL Copyright RIGHTS RESERVED.
Page 8: Safety Information
Safety Information Statement Your Milli-Q System should be operated according to the instructions in this manual. In particular, the hydraulic and electrical specifications should be followed and met. It is important to use this equipment as specified in this manual; using this equipment in a different manner may impair the safety precautions of the Milli-Q System.
Page 9: Where To Find Information
Where to find information Organisation of This block will explain how this manual is organised. this User Manual Cross reference This block will contain a cross reference table. The table will be a quick way table for the reader to find information about items that might have different names than those used in this manual.
Page 10: Product Information
Product Information Overview Purpose This chapter contains topics related to the Milli-Q System. Some of the more important topics in this chapter are: • Installation requirements • Consumable information • Dimensions of various components of the Milli-Q System Contents This chapter contains the following topics:...
Page 11: Cabinet
Cabinet Description Part Function Main Display LEDs Main Keypad Door for Quantum Cartridge Door for Progard Pack Connections for ports and cables Ports and cables...
Page 12 Port 8 Water to E-POD tubing to drain Dispenser (Accessory) Port 2 Feedwater to Port 9 Water to and Milli-Q System from Reservoir Port 3 Water to Q-POD Power Cord Dispenser (100 – 240 V) Port 4 Water from Q-...
Page 13: Q-Pod Dispenser
Q-POD Dispenser Description Part Function Plunger POU Dispenser POD Pak (BioPak Ultrafilter pictured here) Mast Base Q-POD Dispenser Display Q-POD Dispenser Keypad Ports and cables Part Function Printer cable connection PS/2 cable connection + Termination Plug connection...
Page 14 Footswitch connection Tubing connections RC-Link The entire RC-Link is pictured here. The RC-Link is the set of tubings and the PS/2 cable inside a sheath. Part Function Termination Plug PS/2 Cable Tubings Height adjustment Step Action Result Press the button on the Q-POD picture here Arm.
Page 15: Tank
Tank Millipore Millipore recommends using a Tank having the following catalogue number: recommends XXXXXXXXX (please list this in the Customised Data File). Example A picture of a Tank alongside a fully installed Milli-Q Integral System will be shown here.
Page 16: Consumables
Consumables Diagram The water flow through a Milli-Q System is shown here in a flow diagram. The various consumables are described below. For more information about the flow diagram, please refer to the Milli-Q System brochure. Please contact Millipore if you would like to have a brochure.
Page 17 POD Pak The POD Pak is a water purification device that is attached to the Q-POD Dispenser outlet. It is the final purification device used before Milli-Q Water is dispensed. The POD Pak provides additional quality and insurance that trace contaminants related to specific applications are removed just before ultrapure water is delivered.
Page 18: Specifications And Requirements
< 0.2 μS/cm@ 25°C Conductivity < 30 ppb Micro-organisms ≤ 1 CFU/ml Product Flow Rate System Flow Rate Milli-Q Integral 3 > 2.5 Lpm Milli-Q Integral 5 > 4.25 Lpm Milli-Q Integral 10 > 8 Lpm Milli-Q Integral 15 > 13 Lpm RO Ionic Typical 94-99%;...
Page 19 Dimensions Note to Millipore reviewer Drawings or photos will be used here with dimensions indicated Materials of Please contact Millipore for a list of the Materials of Construction. construction Feedwater The Feedwater requirements are listed here. Item Description Aluminum <...
Page 20 50% relative humidity at 40°C. Consumables The consumable requirements for installation are: • 1 Progard Pack • 1 Quantum Cartridge • 1 POD Pak Note: Please note that these items are not included with the Milli-Q System.
Page 21: Installation
Installation Overview Purpose The purpose of this chapter is to explain how to install the Milli-Q System. Contents This chapter contains the following topics: Topic See Page Mechanical installation Consumable installation Software used during installation...
Page 22: Mechanical Installation
Mechanical installation Overview Purpose The purpose of this section is to explain how to perform the mechanical tasks associated with the Milli-Q System installation. Contents This section contains the following topics: Topic See Page Q-POD Dispenser Main Cabinet tubings, cables and power cord...
Page 23: Q-Pod Dispenser
Q-POD Dispenser Assembly Step Action Result Open the Q-POD Dispenser picture will be shown here box. Locate the Q-POD Dispenser base and the Q-POD Dispenser mast. Screw them together picture will be shown here Locate the Q-POD Dispenser picture will be shown here arm.
Page 24 Important! Make sure the PS/2 cable and the Termination Plug are well connected to the Q-POD Dispenser.
Page 25: Main Cabinet Tubings, Cables And Power Cord
Milli-Q System Cabinet. Important! Fill The Milli-Q System automatically displays a TANK EMPTY Alarm when Tank partially there is no water in the Tank. The Tank is empty when the Milli-Q System is before being installed. proceeding To avoid this alarm during the installation of the Milli-Q System, put 10-20 litres of water in the Tank before powering the Milli-Q System.
Page 26 Displays shown The following table describes the first displays shown when the Milli-Q when powering System is powered on. the system Description Main Display Q-POD Display The Main Display and the Q-POD Display look like the LCDs shown to the right.
Page 27: Consumable Installation
Consumable installation Overview Purpose The purpose of this section is to explain how to install the consumables. Contents This section contains the following topics: Topic See Page Installing/flushing the Progard Pack, rinsing the RO Installing the Quantum Cartridge Installing a POD Pak...
Page 28: Installing/Flushing The Progard Pack, Rinsing The Ro
Important! The Milli-Q System automatically displays a TANK EMPTY Alarm when there is no water in the Tank. The Tank is empty when the Milli-Q System is being installed. To avoid this alarm during the installation of the Milli-Q System, put 10-20 litres of water in the Tank before powering the Milli-Q System.
Page 29 Milli-Q System goes to READY Mode. Flushing and When the Milli-Q System is newly installed, or if a RO Cartridge(s) is rinsing the RO replaced, the RO Cartridge(s) must be flushed out. Failure to do this Cartridge(s) procedure completely results in high TOC values of the product water.
Page 30 RO. Press A picture is shown. Press Press Press After 15 minutes, the LCD looks like this. When the 225 minute RO rinse is finished, the Milli-Q System returns to READY Mode. The Tank is now being filled automatically.
Page 31 Allow the Tank to fill until it contains at least 10-15 litres of water. This water is needed for the Quantum Cartridge flush in the next part of this User Manual. Note that the Alarm message QUANTUM CARTRIDGE OUT is displayed. This is normal.
Page 32: Installing The Quantum Cartridge
Quantum Cartridge being installed. Close the right door. Picture here showing the right door closed. The Milli-Q System sees that a new Quantum Cartridge is installed. Note that your Catalogue Number and Lot Number maybe different than those values shown here.
Page 33 Place the other fitting. end of the clear tubing into a sink. The Milli-Q System should be in READY Mode. Push the plunger down on the Q-POD Dispenser. In a few minutes, water should dispense from the Q-POD Dispenser.
Page 34 Afterwards, dispense water for about 10 minutes. Leave the Milli-Q System in READY Mode when finished.
Page 35: Installing A Pod Pak
Installing a POD Pak Placing Follow the instructions delivered with the POD Pak. Registering The POD Pak installation has to be registered. Follow the steps below to register the installation of the POD Pak. Step Action Result Start in STANDBY Mode. Select Menu.
Page 36 Press In this example, you choose Millipak. Press Press Press Press 3 times...
Page 37: Software Used During Installation
Software used during installation Overview Purpose The purpose of this section is to explain how to use the software necessary during installation. Other software functions are explained in the software chapter of this User Manual. Contents This section contains the following topics: Topic See Page Cleaning the A10 TOC Monitor...
Page 38: Cleaning The A10 Toc Monitor
Cleaning the A10 TOC Monitor Purpose The A10 TOC Monitor should be cleaned when a new Quantum Cartridge is installed. Procedure Follow the steps below to clean the A10 TOC Monitor. Step Action Result Start in STANDBY Mode. Select Menu. Press Select Sanitise/Clean...
Page 39 When the A10 CLEANING Mode has finished, the Milli-Q System automatically goes into READY Mode.
Page 40: Registering Uv Lamp Timers
Registering UV Lamp timers Purpose The timer used for each UV Lamp must be reset when the Milli-Q System is installed. If this is not done, then the Milli-Q System will prematurely remind you that a particular UV Lamp needs to be replaced.
Page 41 Press Press Press Press times on Important Repeat the same procedure for the • UV 185 nm Lamp, and • the A10 TOC Monitor Lamp.
Page 42: Flow Calibration
Flow Calibration Purpose The Milli-Q Water flowrate should be calibrated when the Milli-Q System is installed. This calibration should be done with Q-POD Dispenser 1 in case there are multiple Q-POD Dispensers. You need a 1 Litre graduated cylinder before starting the Flow Calibration.
Page 43 Place a 1 L Graduated Cylinder under the Q- POD. Press Look at the Q- Dispenser Keypad. Press Water dispenses automatically from Q-POD Dispenser 1. Wait until the Task Completion is completed Measure the amount of water (in ml) that was dispensed. Suppose 870 ml was collected.
Page 44: Software
Software Overview Purpose The purpose of this chapter is to explain the various software used in the Milli-Q System. Contents This chapter contains the following topics: Topic See Page Software Map Standby Mode Manager Menu Ready Mode...
Page 45: Section A
Section A Software Map...
Page 46: Section B
Section B Standby Mode Overview Purpose The purpose of this section is to explain Standby Mode. Contents This section contains the following topics: Topic See Page Standby Mode - General information Description of Standby Menu...
Page 47: Standby Mode - General Information
Standby Mode - General information Purpose This mode is used primarily for: • Maintenance actions, and • Accessing the Manager Menu. The Manager Menu is explained in a different section of this chapter. Display Main Display Q-POD Display Switching to Ready Mode Display Action...
Page 48: Description Of Standby Menu
Description of Standby Menu Maintenance The Maintenance Menu is described below. Display Display Item Description Install Pretreatment Used to reset timer for pretreatment. Clean Strainer Used to reset Alert message ‘EXAMINE INLET STRAINER’. Install Progard Used to see general information about the Progard Pack exchange.
Page 49 Used for sanitising the RO Cartridge(s). RO pH Cleaning Used for cleaning the RO Cartridge(s). A10 Cleaning Used to clean the A10 TOC Monitor. System Cleaning Contact Millipore for more information. Suitability Tests Display Display Item Description Res Suitability Test Contact Millipore for more information.
Page 50 Item Description English and other languages Used to change language displayed on the Main Display. Manager Menu Display Display See the next section in this chapter for information about the Manager Menu.
Page 51: Manager Menu
Manager Menu Overview Purpose The purpose of this section is to explain the Manager Menu. Contents This section contains the following topics: Topic See Page Description of Manager Menu...
Page 52: Description Of Manager Menu
CHANGE ID & PASSWORD Used to change the Login and Password used to enter the Manager Menu. Date and Time Display Display Item Description DATE AND TIME Used to change the Milli-Q System date and time. Set Points Display Display...
Page 53 Item Description Pretreatment Strainer Frequency Tap Feed Cond RO Rejection Permeate Cond Elix Product Res Tank Refill Milli-Q Product Res Milli-Q Product TOC Millipak BioPak POD Pak A POD Pak B POD Pak C Units Display Display Item Description Pressure...
Page 54 Item Description Install Date Buzzer MQ Recirc Mode POD Flow Stop Temp Comp Flow Calibration UV 254 nm Activation UV 185 nm Activation ASM UV Lamp Schedule Network Settings User Parameters Display Display Item Description Company Name Department Name Address Postal Code City Country...
Page 55 History Summary Display Display Item Description History Summary Print System History Print Elix History Print Milli-Q History Print Options Printing the History Step Action Result...
Page 56: Ready Mode
Ready Mode Overview Purpose The purpose of this section is to explain READY Mode. Contents This section contains the following topics: Topic See Page Ready Mode - General information Description of Ready Menu...
Page 57: Ready Mode - General Information
Ready Mode - General information Purpose In READY Mode, water can be dispensed from the Q-POD Plunger. The Milli-Q System should be left in READY Mode most of the time. Display Main Display Q-POD Display Display needs to be drawn.
Page 58: Description Of Ready Menu
Description of Ready Menu Water Quality Display Display Item Description Water Quality Print Menu View Operation Consumables Status Call Millipore Service Tracking Information Print Menu Display Display Item Description MQ Instant Quality Elix Instant Quality View Operation Display Display...
Page 59 System Alarms System Measures Consumables Status Display Display Item Description Pretreatment Progard UV 254 nm Lamp ASM UV Lamp UV 185 nm Lamp Quantum A10 UV Lamp POD Pak 1 (2) (3) Call Millipore Display Display Item Description Application Specialist...
Page 60 Service Engineer Tech Service Other Service Tracking Display Display Item Description Installation Repair Service Contract Contract Expires Next Service Next Calibration Next Qualification Information Display Display Item Description Flow Schematic Version System Information...
Page 61: Using The Milli-Q System
Purpose The purpose of this chapter is to explain: • various ways that water can be dispensed from the Milli-Q System, • how to understand the Main Keypad, Display and LEDs, and • how to understand the Q-POD Keypad and its display...
Page 62: Dispensing Water
High Flow (push down and hold or push down and release) Volumetric Follow the steps below to volumetrically dispense from the Q-POD dispensing Dispenser. Step Action Result Footswitch It is possible to use a Footswitch accessory with the Q-POD Dispenser. Contact Millipore for more information.
Page 63: Main Keypad, Display And Leds
Main Keypad, Display and LEDs Description A picture will be shown here. This picture will show the Main Display, the Keypad and LEDs. A table will be used to identify the various parts. Keypad – right The RIGHT Keypad button is described below. Display Action Result...
Page 64 Press LEDs A picture or drawing of the LEDs will be shown here. Item Description Green LED Milli-Q System has no Alarms or Alerts. Yellow LED An Alert is present. Red LED An Alarm is present. Note: If an Alarm and an Alert are present at the same time, then only the red LED...
Page 65: Q-Pod Keypad And Display
Q-POD Keypad and Display Description A picture or drawing of the entire Q-POD Keypad and Display will be shown here along with a table labelling the main components. Keypad A picture or drawing of the Q-POD Keypad will be shown here along with a table labelling the various keypad buttons.
Page 66: Maintenance
Maintenance Overview Purpose The purpose of this chapter is to explain the common maintenance needed for a Milli-Q System. Contents This chapter contains the following topics: Topic See Page Maintenance Schedule Replacing the Progard Pack Replacing the Quantum Cartridge Replacing a POD Pak...
Page 67: Maintenance Schedule
Lamp an LCD message. Note It is recommended to have a Millipore Field Service Representative change the various lamps in the system. The replacement of these lamps involves removing the cover of the system. The instructions for replacing these lamps are not included in this User Manual.
Page 68: Replacing The Progard Pack
Result Open the left door of the Milli- picture here showing the left Q System Cabinet. door open. Open the Milli-Q System left picture here. door. Lift up the Pack Locking Handle. Remove the used Progard Pack. picture here. The system will indicate that the Progard Pack is removed.
Page 69 The Milli-Q System sees that a new Progard Pack is installed. Note that your Catalogue Number and Lot Number maybe different than those values shown here. Go to the next set of steps to flush the Progard Pack. Flushing The Progard Pack must be flushed out when it is newly installed. Follow the steps below.
Page 70: Replacing The Quantum Cartridge
The Quantum Cartridge should be replaced when one of the following Alert or Alarm messages is displayed. • Alert message = REPLACE QUANTUM CARTRIDGE • Alarm message = MILLI-Q RES < SP, REPLACE QUANTUM Removing Follow the steps below to remove the used Quantum Cartridge.
Page 71 Step Action Result Locate the clear tubing and the picture here of these items. barbed fitting from the Milli-Q System Accessories Bag. Screw the barbed fitting onto picture here showing the barbed the Q-POD Dispenser. fitting installed on the end of the Q-POD Dispenser.
Page 72 Q-POD Dispenser. Leave the Milli-Q System in READY Mode overnight or for several hours (> 6 hours). This allows the purification media in the Q-Gard Pack and Quantum Cartridge to hydrate.
Page 73: Replacing A Pod Pak
Replacing a POD Pak Replacement One possible reason for a decrease in Milli-Q Water flowrate is a clogged based on POD Pak. The POD Pak should be replaced when it appears to be clogged. flowrate Make sure the POD Pak is not air-locked. Dispense water and open the vent to see if there is any trapped air.
Page 74 Select Menu. Press Select Maintenance. Press Scroll down until you see Install Q-POD Pak 1. Select it. Press Press In this example, you choose Millipak. Press Press...
Page 75 Press Press 3 times...
Page 76: Cleaning The A10 Toc Monitor
Cleaning the A10 TOC Monitor When There is no LCD message indicating that an A10 TOC Monitor cleaning is needed. Purpose The A10 TOC Monitor cleaning is recommended when: • A new Q-Gard Pack or Quantum Cartridge is installed, • the TOC values are fluctuating, or •...
Page 77 Press When the A10 CLEANING Mode has finished, the Milli-Q System automatically goes into READY Mode.
Page 78: Sanitising Or Cleaning The Ro Cartridge
Sanitising or cleaning the RO Cartridge Safety Wear Eye Safety Glasses and Laboratory Gloves and other appropriate safety equipment when sanitising or cleaning the RO Cartridge(s). Opening and closing the Step Action Result Sanitisation Port Sanitising Step Action Result Cleaning Step Action Result...
Page 79: Cleaning The Inlet Strainer
Purpose The purpose of the Inlet Strainer is to prevent a large particle from entering the Milli-Q System. If the Inlet Strainer becomes clogged, then feedwater does not flow freely to the Milli-Q System. Cleaning the Inlet Strainer removes any trapped debris.
Page 80: Replacing The Tank Vent Filter
Replacing the Tank Vent Filter When The Tank Vent Filter should be replaced when one of the following Alert messages is displayed. • Alert message = REPLACE PROGARD AND TANK VENT FILTER • Alert message = REPLACE PROGARD AND TANK VENT FILTER OVERDUE X DAYS, where X = 1, 2, …...
Page 81: Alarms And Alerts
Alarms and Alerts Overview Purpose The purpose of this chapter is to explain the various Alarm and Alert messages shown on the Milli-Q System. Contents This chapter contains the following topics: Topic See Page Alert messages Alarm messages Summary of Alert and Alarm messages...
Page 82: Alert Messages
Alert messages Purpose An Alert message corresponds to a maintenance request. Most of the Alert messages are related to the changing of a consumable. Types The following table summarizes the different types of Alert messages. Type Description • A minor alert message corresponds to an early Minor Alert maintenance request.
Page 83: Alarm Messages
Some Alarms, when displayed, do not automatically Milli-Q System stop the Milli-Q System from dispensing water. An example of this is the Alarm message MILLI-Q T < MIN. This type of Alarm message can be cancelled for one hour by using the Keypad.
Page 84: Summary Of Alert And Alarm Messages
Contact Millipore. CHECK UV 254 NM LAMP The UV 254 nm Lamp is not turning Contact Millipore. EDI LOW INTENSITY The Milli-Q System has determined that the electrical intensity used by the EDI Module is below specification. EXAMINE INLET STRAINER...
Page 85 LCD message What it means A10 ERROR 0 A10 PCB E2Prom defective. Unplug the power cord, and then plug it in to power on the Milli-Q System. Dispense water for several minutes. If the message continues, then contact Millipore. A10 ERROR 1 A10 PCB A/D converter defective.
Page 86 If the message continues, then contact Millipore. A10 ERROR 2 A10 Thermistor defective. Unplug the power cord, and then plug it in to power on the Milli-Q System. Dispense water for several minutes. If the message continues, then contact Millipore. A10 ERROR 3 Problem occurred with temperature compensation.
Page 87 9 minutes. A new TOC Analysis is done during this time. If the new TOC value is satisfactory, then proceed to use the Milli-Q Water. CLEANING CANCELLED ELIX PRODUCT R < SP The Elix Water resistivity is < set point.
Page 88 RO FEED T > MAX The Feedwater Water temperature is out of measurement range. Contact Millipore. TANK EMPTY The Milli-Q System has detected an empty tank. Refill the tank. Verify that the tank level sensor is plugged into the Milli-Q System Cabinet.
Page 89: Ordering Information
ZMQSP0D01 Water Sensor ZFWATDET4 Milli-Q Integral System Cabinet Item Catalogue Number Milli-Q Integral 3 ZRXQ003T0 Milli-Q Integral 5 ZRXQ005T0 Milli-Q Integral 10 ZRXQ010T0 Milli-Q Integral 15 ZRXQ015T0 Note: A complete Milli-Q Integral System consists of : • a Q-POD Dispenser...
Page 90 • a Tank, and • a Milli-Q Integral System Cabinet...

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